(Q24337108)

GOA release 2020-03-11

BCL2 modifying factor

1 reference

Phorbol-12-myristate-13-acetate-induced protein 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Victoria Del Gaizo Moore

object named as

Victoria Del Gaizo Moore

2

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Stanley J. Korsmeyer

5

object named as

Stanley Korsmeyer

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author name string

Michael Certo

1

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Mari Nishino

3

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Guo Wei

4

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Scott A Armstrong

6

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Anthony Letai

Bax conformational change is a crucial step for PUMA-mediated apoptosis in human leukemia.

7

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language of work or name

English

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publication date

May 2006

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published in

Cancer Cell

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volume

9

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issue

5

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page(s)

351-65

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Antiapoptotic BCL-2 is required for maintenance of a model leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

BH3-Only proteins-essential initiators of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Cell death: critical control points

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Bcl-2-family proteins: the role of the BH3 domain in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

A matter of life and death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Underphosphorylated BAD interacts with diverse antiapoptotic Bcl-2 family proteins to regulate apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Bax-independent inhibition of apoptosis by Bcl-XL.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Senescence, apoptosis and therapy--cutting the lifelines of cancer.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Bim is a suppressor of Myc-induced mouse B cell leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Suppression of tumorigenesis by the p53 target PUMA

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Nonionic detergents induce dimerization among members of the Bcl-2 family

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Bim: a novel member of the Bcl-2 family that promotes apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

BID: a novel BH3 domain-only death agonist

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Cancer. Addiction to oncogenes--the Achilles heal of cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021

Characterization of the antiapoptotic Bcl-2 family member myeloid cell leukemia-1 (Mcl-1) and the stimulation of its message by gonadotropins in the rat ovary

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2006.03.027

7 January 2021