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p53: 25 years after its discovery
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scholarly article
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Europe PubMed Central
title
p53: 25 years after its discovery
(English)
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author
S. Perwez Hussain
series ordinal
2
object named as
S Perwez Hussain
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author name string
Lorne J Hofseth
series ordinal
1
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Curtis C Harris
series ordinal
3
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language of work or name
English
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publication date
April 2004
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published in
Trends in Pharmacological Sciences
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volume
25
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issue
4
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page(s)
177-81
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cites work
TP53 and breast cancer
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TP53 mutation in colorectal cancer
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Introduction: p53--the first twenty years
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
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Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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p53, the cellular gatekeeper for growth and division
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Small molecules that reactivate mutant p53.
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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p53 has a direct apoptogenic role at the mitochondria
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p53 as a therapeutic target: unresolved issues on the road to cancer therapy targeting mutant p53.
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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p53 leans on its siblings
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p53 and regulation of DNA damage recognition during nucleotide excision repair
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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7 January 2021
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T antigen is bound to a host protein in SY40-transformed cells
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Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
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The p53 tumour suppressor gene
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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
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Cancer-susceptibility genes. Gatekeepers and caretakers
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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p53 mutant mice that display early ageing-associated phenotypes
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
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Nucleolar Arf sequesters Mdm2 and activates p53
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression
1 reference
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Live or let die: the cell's response to p53
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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7 January 2021
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Targeting gene expression to tumor cells with loss of wild-type p53 function
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Activation of p53 by roscovitine-mediated suppression of MDM2 expression
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Deconstruction of p53 functions and regulation
1 reference
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Exploiting the p53 pathway for cancer diagnosis and therapy
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7 January 2021
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Post-translational modifications and activation of p53 by genotoxic stresses
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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation
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Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases
1 reference
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse
1 reference
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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A role for p53 in base excision repair.
1 reference
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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7 January 2021
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"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally
1 reference
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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7 January 2021
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Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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7 January 2021
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p53 mutations in human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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7 January 2021
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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
1 reference
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene
1 reference
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https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Apoptosis - the p53 network
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.TIPS.2004.02.009
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Identifiers
DOI
10.1016/J.TIPS.2004.02.009
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PubMed ID
15116721
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