(Q37088668)

18 August 2017

Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide (English)

1 reference

18 August 2017

5

Alan R Fersht

1 reference

18 August 2017

6

Galina Selivanova

1 reference

18 August 2017

Natalia Issaeva

1

1 reference

18 August 2017

Assaf Friedler

series ordinal

2

1 reference

18 August 2017

Przemyslaw Bozko

series ordinal

3

1 reference

18 August 2017

Klas G Wiman

series ordinal

4

1 reference

18 August 2017

language of work or name

English

0 references

publication date

31 October 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

1 reference

18 August 2017

100

1 reference

18 August 2017

13303-13307

1 reference

18 August 2017

23

1 reference

18 August 2017

Drug discovery and p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at serine 15 or 20 or MDM2 binding.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Activation of the p53 tumor suppressor protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Therapeutic exploitation of the p53 pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Rescuing the function of mutant p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Mutant p53: the loaded gun.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

29 September 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Hot-spot mutants of p53 core domain evince characteristic local structural changes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Thermodynamic stability of wild-type and mutant p53 core domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Characterization of the p53-rescue drug CP-31398 in vitro and in living cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=263793

Kinetic Instability of p53 Core Domain Mutants

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1835733100

Pharmacological rescue of mutant p53 conformation and function

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14595027

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1835733100

1 reference

18 August 2017

0 references

1 reference

18 August 2017

1 reference