(Q24339492)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24656772%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

title

SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24656772%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

0 references

1 reference

2

1 reference

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11 March 2020

Jing Zhang

8

1 reference

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11 March 2020

Yong Tian

22

1 reference

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11 March 2020

Brenda Schulman

23

1 reference

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11 March 2020

Jiang Liu

24

1 reference

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11 March 2020

author name string

Subhradip Karmakar

3

1 reference

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11 March 2020

Ke Chen

4

1 reference

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11 March 2020

Ruby Dhar

5

1 reference

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11 March 2020

Zhixiang Fan

6

1 reference

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11 March 2020

Zhongqiang Guo

7

1 reference

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11 March 2020

Yuwen Ke

9

1 reference

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11 March 2020

Lu Wang

10

1 reference

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11 March 2020

Min Zhuang

11

1 reference

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11 March 2020

Shengdi Hu

12

1 reference

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11 March 2020

Xuesong Li

13

1 reference

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11 March 2020

Liqun Zhou

14

1 reference

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11 March 2020

Xianghong Li

15

1 reference

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11 March 2020

Matthew F Calabrese

16

1 reference

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11 March 2020

Edmond R Watson

17

1 reference

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11 March 2020

Sandip M Prasad

18

1 reference

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11 March 2020

Carrie Rinker-Schaeffer

19

1 reference

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11 March 2020

Scott E Eggener

20

1 reference

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11 March 2020

Thomas Stricker

21

1 reference

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11 March 2020

Kevin P White

25

1 reference

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11 March 2020

Guoqiang Li

1

1 reference

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11 March 2020

language of work or name

English

0 references

publication date

20 March 2014

1 reference

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11 March 2020

1 reference

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11 March 2020

volume

25

1 reference

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11 March 2020

page(s)

455-468

1 reference

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11 March 2020

issue

4

1 reference

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on focus list of Wikimedia project

11 March 2020

ScienceSource

0 references

cites work

Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1

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Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

19 March 2017

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Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase

19 March 2017

1 reference

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Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells

19 March 2017

1 reference

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The mitochondrial ARTS protein promotes apoptosis through targeting XIAP

19 March 2017

1 reference

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The lipid phosphatase activity of PTEN is critical for its tumor supressor function

19 March 2017

1 reference

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Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

19 March 2017

1 reference

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Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

19 March 2017

1 reference

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Integrated molecular analysis of clear-cell renal cell carcinoma

19 March 2017

1 reference

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Comprehensive molecular characterization of clear cell renal cell carcinoma

19 March 2017

1 reference

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Identification of a novel nuclear speckle-type protein, SPOP

19 March 2017

1 reference

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Sorafenib in advanced clear-cell renal-cell carcinoma

19 March 2017

1 reference

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Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

19 March 2017

1 reference

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Daxx: death or survival protein?

19 March 2017

1 reference

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The biology and clinical relevance of the PTEN tumor suppressor pathway

19 March 2017

1 reference

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Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes

19 March 2017

1 reference

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Molecular basis of the VHL hereditary cancer syndrome

19 March 2017

1 reference

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Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

19 March 2017

1 reference

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

19 March 2017

1 reference

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Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

7 April 2017

1 reference

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MAP kinase signalling pathways in cancer

7 April 2017

1 reference

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Growing roles for the mTOR pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial

7 April 2017

1 reference

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Protein localization in disease and therapy.

27 September 2017

1 reference

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Interplay between pVHL and mTORC1 pathways in clear-cell renal cell carcinoma.

27 September 2017

1 reference

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PTEN loss in the continuum of common cancers, rare syndromes and mouse models.

27 September 2017

1 reference

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Phosphorylation meets nuclear import: a review

27 September 2017

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Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors

27 September 2017

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Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus

27 September 2017

1 reference

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Targeted inhibition of mammalian target of rapamycin for the treatment of advanced renal cell carcinoma

27 September 2017

1 reference

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Dual-specificity phosphatases: critical regulators with diverse cellular targets

27 September 2017

1 reference

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Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer.

27 September 2017

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The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

27 September 2017

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Phosphorylation of ERK1/2 and prognosis of clear cell renal cell carcinoma

27 September 2017

1 reference

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Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Dual-specificity MAP kinase phosphatases (MKPs) and cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Stability of checkpoint kinase 2 is regulated via phosphorylation at serine 456.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

2004 WHO classification of the renal tumors of the adults

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Role of VHL gene mutation in human cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Renal-cell carcinoma--molecular pathways and therapies.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Targeting renal cell carcinoma.

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Oxidants inhibit ERK/MAPK and prevent its ability to delay neutrophil apoptosis downstream of mitochondrial changes and at the level of XIAP.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

Loss of tumor suppressor protein PTEN during renal carcinogenesis.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4443692

29 November 2018

1 reference

12 December 2020

Phosphorylation profiles of protein kinases in alveolar and embryonal rhabdomyosarcoma

1 reference

12 December 2020

Activation of the mTOR signaling pathway in renal clear cell carcinoma

1 reference

12 December 2020

Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma. Groupe Français d'Immunothérapie

1 reference

12 December 2020

Long-term response data for 255 patients with metastatic renal cell carcinoma treated with high-dose recombinant interleukin-2 therapy

1 reference

12 December 2020

Cyclophosphamide pulse therapy in relapsing nephrotic syndrome

1 reference

12 December 2020

Activated extracellular signal-regulated kinase is an independent prognostic factor in clinically confined renal cell carcinoma

1 reference

12 December 2020

The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase.

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CCR.2014.02.007

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.CCR.2014.02.007

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24656772%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24656772%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24656772%20AND%20SRC:MED&resulttype=core&format=json