(Q24537406)

English

Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ.

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Europe PubMed Central

PubMed publication ID

6 July 2017

Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ. (English)

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Europe PubMed Central

PubMed publication ID

6 July 2017

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quality control

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Kristina B. Kruse

1

object named as

Kristina B Kruse

author given names

Kristina B

author last names

Kruse

1 reference

PubMed publication ID

20 October 2023

Ardythe A. McCracken

3

object named as

Ardythe A McCracken

author given names

Ardythe A

author last names

McCracken

1 reference

PubMed publication ID

20 October 2023

author name string

Jeffrey L Brodsky

2

author given names

Jeffrey L

author last names

Brodsky

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Europe PubMed Central

PubMed publication ID

6 July 2017

language of work or name

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publication date

2 November 2005

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Molecular Biology of the Cell

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Europe PubMed Central

PubMed publication ID

6 July 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

203-212

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Grp78, Grp94, and Grp170 interact with alpha1-antitrypsin mutants that are retained in the endoplasmic reticulum

1 reference

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Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

1 reference

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1 reference

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Liver injury in alpha1-antitrypsin deficiency: an aggregated protein induces mitochondrial injury

1 reference

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Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy

1 reference

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A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast

1 reference

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24 March 2017

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

1 reference

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Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast

1 reference

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24 March 2017

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1 reference

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24 March 2017

Differential requirements of novel A1PiZ degradation deficient (ADD)genes in ER-associated protein degradation

1 reference

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1 reference

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24 March 2017

Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase

1 reference

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24 March 2017

Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

A regulatory link between ER-associated protein degradation and the unfolded-protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

1 reference

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24 March 2017

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Multifunctional yeast high-copy-number shuttle vectors

1 reference

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24 March 2017

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli

1 reference

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1 reference

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24 March 2017

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1 reference

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24 March 2017

Aggresomes: a cellular response to misfolded proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

24 March 2017

Development by self-digestion: molecular mechanisms and biological functions of autophagy

1 reference

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7 April 2017

Autophagy as a regulated pathway of cellular degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

7 April 2017

A trip to the ER: coping with stress

1 reference

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7 April 2017

Aggresomes, inclusion bodies and protein aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

7 April 2017

Checkpoints in ER-associated degradation: excuse me, which way to the proteasome?

1 reference

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27 September 2017

Degradation of mutated bovine pancreatic trypsin inhibitor in the yeast vacuole suggests post-endoplasmic reticulum protein quality control

1 reference

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Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

27 September 2017

Dependence of endoplasmic reticulum-associated degradation on the peptide binding domain and concentration of BiP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

27 September 2017

Stress tolerance of misfolded carboxypeptidase Y requires maintenance of protein trafficking and degradative pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

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Alpha1-antitrypsin deficiency: liver disease associated with retention of a mutant secretory glycoprotein in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

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For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

27 September 2017

ER-associated degradation in protein quality control and cellular regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

27 September 2017

Secretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

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ER-golgi traffic is a prerequisite for efficient ER degradation.

1 reference

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1 reference

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Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

1 reference

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27 September 2017

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1 reference

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Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

27 September 2017

Role of ubiquitin in proteasomal degradation of mutant alpha(1)-antitrypsin Z in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

27 September 2017

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1 reference

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27 September 2017

A pathway for targeting soluble misfolded proteins to the yeast vacuole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

27 September 2017

Selective protein degradation in the yeast exocytic pathway

1 reference

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27 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

27 September 2017

Protein transport to the yeast vacuole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

27 September 2017

PEP4 gene function is required for expression of several vacuolar hydrolases in Saccharomyces cerevisiae

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27 September 2017

Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy

1 reference

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27 September 2017

The mechanism of Z alpha 1-antitrypsin accumulation in the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

27 September 2017

Molecular pathogenesis of liver disease in alpha1-antitrypsin deficiency

1 reference

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27 September 2017

Different degradation pathways for heterologous glycoproteins in yeast

1 reference

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30 May 2018

Yeast mutants deficient in ER-associated degradation of the Z variant of alpha-1-protease inhibitor.

1 reference

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30 May 2018

Glycosylation and secretion of human alpha-1-antitrypsin by yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1345659

19 June 2018

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1 reference

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29 November 2018

Multiple sorting pathways between the late Golgi and the vacuole in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The requirement for molecular chaperones during endoplasmic reticulum-associated protein degradation demonstrates that protein export and import are mechanistically distinct

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Kinetic Mechanism for the Polymerization of α1-Antitrypsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand recognition and domain structure of Vps10p, a vacuolar protein sorting receptor in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retention of mutant alpha(1)-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A naturally occurring nonpolymerogenic mutant of alpha 1-antitrypsin characterized by prolonged retention in the endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional characterization of the abnormal Z alpha 1-antitrypsin isolated from human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The natural history of liver disease in alpha 1-antitrypsin deficient children

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of a mutant secretory protein, alpha1-antitrypsin Z, in the endoplasmic reticulum requires proteasome activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16267277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CFTR expression and ER-associated degradation in yeast

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E04-09-0779

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1091/MBC.E04-09-0779

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

release_awgex4rt5vevxejg4aaj5z2x6u

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

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