(Q24551184)

2

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James D Kelly

3

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Robert K Winn

4

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John M Harlan

Journal of Clinical Investigation

5

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language of work or name

English

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publication date

February 2002

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published in

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volume

109

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issue

3

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page(s)

419-25

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cites work

The apoptotic signaling pathway activated by Toll-like receptor-2

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A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

24 March 2017

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Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

24 March 2017

1 reference

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Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

24 March 2017

1 reference

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

24 March 2017

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Activation of the NF-kappaB pathway by caspase 8 and its homologs

24 March 2017

1 reference

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Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

24 March 2017

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FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

24 March 2017

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The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells

24 March 2017

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Interleukin 20: discovery, receptor identification, and role in epidermal function

24 March 2017

1 reference

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Drosophila MyD88 is an adapter in the Toll signaling pathway

24 March 2017

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Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway

27 September 2017

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Modulation of the nuclear factor kappa B pathway by Shp-2 tyrosine phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumor necrosis factor

27 September 2017

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Interleukin-1/Toll receptor family members: receptor structure and signal transduction pathways

27 September 2017

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Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6.

27 September 2017

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Activation of NF-kappaB by FADD, Casper, and caspase-8.

27 September 2017

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Regulatory roles for CD14 and phosphatidylinositol in the signaling via toll-like receptor 4-MD-2.

27 September 2017

1 reference

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Negative regulation by phosphatidylinositol 3-kinase of inducible nitric oxide synthase expression in macrophages

27 September 2017

1 reference

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Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction

27 September 2017

1 reference

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A critical role for the RelA subunit of nuclear factor kappaB in regulation of multiple immune-response genes and in Fas-induced cell death

27 September 2017

1 reference

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Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells

27 September 2017

1 reference

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Lipopolysaccharide mediates endothelial apoptosis by a FADD-dependent pathway

27 September 2017

1 reference

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Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin

27 September 2017

1 reference

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c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150862

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150862

Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150862

Endotoxemia in human septic shock

30 May 2018

1 reference

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HMEC-1: establishment of an immortalized human microvascular endothelial cell line

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150862

A constitutive cytoprotective pathway protects endothelial cells from lipopolysaccharide-induced apoptosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150862

NF-kappaB activation is required for human endothelial survival during exposure to tumor necrosis factor-alpha but not to interleukin-1beta or lipopolysaccharide

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150862

Trends in infectious diseases mortality in the United States.

28 November 2018

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I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

28 November 2018

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12 December 2020

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

1 reference

12 December 2020

Lipopolysaccharide-induced NF-kappaB activation in human endothelial cells involves degradation of IkappaBalpha but not IkappaBbeta

1 reference

12 December 2020

Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells

1 reference

12 December 2020