(Q24554351)

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Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies

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Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies (English)

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Christian Haass

14

object named as

Christian Haass

author given names

Christian

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Haass

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PubMed publication ID

25 October 2023

John Q. Trojanowski

12

object named as

John Q Trojanowski

author given names

John Q

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Trojanowski

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PubMed publication ID

25 October 2023

Manuela Neumann

1

object named as

Manuela Neumann

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Manuela

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Neumann

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PubMed publication ID

25 October 2023

author name string

Philipp J Kahle

2

author given names

Philipp J

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Kahle

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PubMed publication ID

25 October 2023

Benoit I Giasson

3

author given names

Benoit I

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Giasson

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PubMed publication ID

25 October 2023

Laurence Ozmen

4

author given names

Laurence

author last names

Ozmen

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PubMed publication ID

25 October 2023

Edilio Borroni

5

author given names

Edilio

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Borroni

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PubMed publication ID

25 October 2023

Will Spooren

6

author given names

Will

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Spooren

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PubMed publication ID

25 October 2023

Veronika Müller

7

author given names

Veronika

author last names

Müller

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PubMed publication ID

25 October 2023

Sabine Odoy

8

author given names

Sabine

author last names

Odoy

1 reference

PubMed publication ID

25 October 2023

Hideo Fujiwara

9

author given names

Hideo

author last names

Fujiwara

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PubMed publication ID

25 October 2023

Masato Hasegawa

10

author given names

Masato

author last names

Hasegawa

1 reference

PubMed publication ID

25 October 2023

Takeshi Iwatsubo

11

author given names

Takeshi

author last names

Iwatsubo

1 reference

PubMed publication ID

25 October 2023

Hans A Kretzschmar

13

author given names

Hans A

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Kretzschmar

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PubMed publication ID

25 October 2023

language of work or name

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publication date

November 2002

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Journal of Clinical Investigation

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110

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10

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1429-39

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Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

Alpha-synuclein in Lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

Alpha-synuclein and neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

Synucleins are a novel class of substrates for G protein-coupled receptor kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

Immunoelectron-microscopic demonstration of NACP/alpha-synuclein-epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

24 March 2017

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

7 April 2017

A Drosophila model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

7 April 2017

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

7 April 2017

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

Biochemical characterization of the core structure of alpha-synuclein filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

alpha-Synuclein is phosphorylated in synucleinopathy lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

The paraffin-embedded tissue blot detects PrP(Sc) early in the incubation time in prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

Multiple system atrophy: a sporadic synucleinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

Regional mapping of prion proteins in brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

Neurotoxicity of beta-amyloid and prion peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

27 September 2017

Where does parkinson disease pathology begin in the brain?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

30 May 2018

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

30 May 2018

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

30 May 2018

Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

30 May 2018

Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

30 May 2018

Contribution of somal Lewy bodies to neuronal death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

30 May 2018

Neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

30 May 2018

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

28 November 2018

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

28 November 2018

Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

28 November 2018

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

28 November 2018

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

28 November 2018

Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

28 November 2018

Alpha-synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome) with widespread cortical and brainstem-type Lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

28 November 2018

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

28 November 2018

Abnormal distribution of the non-Abeta component of Alzheimer's disease amyloid precursor/alpha-synuclein in Lewy body disease as revealed by proteinase K and formic acid pretreatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

28 November 2018

Lewy body in neurodegeneration with brain iron accumulation type 1 is immunoreactive for alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151810

28 November 2018

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Starnberg trial on epidemiology of Parkinsonism and hypertension in the elderly. Prevalence of Parkinson's disease and related disorders assessed by a door-to-door survey of inhabitants older than 65 years

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathology in mice expressing human alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pure autonomic failure in association with human alpha-synucleinopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI15777

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10.1172/JCI200215777

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Consolidated OpenCitations Corpus – April 2017

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release_tdkovxjpvfct5kyrjurt5v7ar4

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release_edmcodkpcffr3ifzgfzckea5se

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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PubMed publication ID

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