(Q24607422)

English

Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator

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Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator (English)

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organic chemistry

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Craig W. Lindsley

12

object named as

Craig W Lindsley

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author name string

Margrith E Mattmann

1

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Haibo Yu

2

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Zhihong Lin

3

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Kaiping Xu

4

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Xiaofang Huang

5

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Shunyou Long

6

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Meng Wu

7

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Owen B McManus

8

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Darren W Engers

9

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Uyen M Le

10

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Min Li

11

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Corey R Hopkins

13

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language of work or name

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publication date

15 September 2012

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Bioorganic & Medicinal Chemistry Letters

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22

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18

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5936-41

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Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433560

7 April 2017

Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433560

27 September 2017

Activation of Kv7 (KCNQ) voltage-gated potassium channels by synthetic compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433560

27 September 2017

The KCNQ1 potassium channel: from gene to physiological function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433560

27 September 2017

KCNQ1 gene mutations and the respective genotype-phenotype correlations in the long QT syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433560

27 September 2017

The long QT syndromes: genetic basis and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433560

27 September 2017

Desensitization of chemical activation by auxiliary subunits: convergence of molecular determinants critical for augmenting KCNQ1 potassium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433560

30 May 2018

Stilbenes and fenamates rescue the loss of I(KS) channel function induced by an LQT5 mutation and other IsK mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433560

30 May 2018

A novel benzodiazepine that activates cardiac slow delayed rectifier K+ currents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433560

30 May 2018

Identifiers

10.1016/J.BMCL.2012.07.060

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