(Q24616983)

English

Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes

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scholarly article

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Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes (English)

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1 reference

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inferred from title

Vladimir I Titorenko

14

object named as

Vladimir I Titorenko

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author name string

Alexander A Goldberg

1

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Vincent R Richard

2

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Pavlo Kyryakov

3

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Simon D Bourque

4

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Adam Beach

5

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Michelle T Burstein

6

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Anastasia Glebov

7

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Olivia Koupaki

8

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Tatiana Boukh-Viner

9

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Christopher Gregg

10

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Mylène Juneau

11

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Ann M English

12

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David Y Thomas

13

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language of work or name

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publication date

July 2010

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2

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7

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393-414

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Extending healthy life span--from yeast to humans

1 reference

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7 April 2017

Caloric restriction delays disease onset and mortality in rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

7 April 2017

Bile acids: regulation of apoptosis by ursodeoxycholic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

7 April 2017

Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

7 April 2017

Extension of chronological life span in yeast by decreased TOR pathway signaling

1 reference

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7 April 2017

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

1 reference

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7 April 2017

Resveratrol improves health and survival of mice on a high-calorie diet

1 reference

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7 April 2017

Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis

1 reference

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7 April 2017

MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae.

1 reference

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7 April 2017

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

1 reference

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7 April 2017

Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

1 reference

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7 April 2017

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

1 reference

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7 April 2017

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

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7 April 2017

SIR2: a potential target for calorie restriction mimetics

1 reference

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7 April 2017

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

1 reference

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7 April 2017

Absence of peroxisomes in mouse hepatocytes causes mitochondrial and ER abnormalities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

7 April 2017

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

7 April 2017

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

1 reference

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7 April 2017

mTOR signaling at a glance

1 reference

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7 April 2017

Induction of autophagy by spermidine promotes longevity

1 reference

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7 April 2017

ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis

1 reference

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7 April 2017

Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

1 reference

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7 April 2017

Global analysis of protein phosphorylation in yeast

1 reference

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7 April 2017

Extended longevity in mice lacking the insulin receptor in adipose tissue

1 reference

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7 April 2017

Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster

1 reference

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27 September 2017

Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Tor directly controls the Atg1 kinase complex to regulate autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

When a theory of aging ages badly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Converging pathways in lifespan regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

The coordination of nuclear and mitochondrial communication during aging and calorie restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

The ageing epigenome: damaged beyond repair?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Bile acids as regulatory molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

An attempt to prevent senescence: a mitochondrial approach.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Role of bile acids and bile acid receptors in metabolic regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Fat metabolism links germline stem cells and longevity in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Aging: ROS or TOR.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Targeting bile-acid signalling for metabolic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Caffeine extends yeast lifespan by targeting TORC1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

MtDNA mutations, functional decline and turnover of mitochondria in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Chronological aging-induced apoptosis in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Apoptosis pathways in fungal growth, development and ageing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Mitochondria-dependent apoptosis in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Aging and survival: the genetics of life span extension by dietary restriction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Stress-response hormesis and aging: "that which does not kill us makes us stronger".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Signaling networks in aging

1 reference

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27 September 2017

Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

An antidepressant that extends lifespan in adult Caenorhabditis elegans

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27 September 2017

Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans

1 reference

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27 September 2017

Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Endocrine regulation of ageing

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27 September 2017

Caloric restriction mimetics: a novel approach for biogerontology

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Alterations in xenobiotic metabolism in the long-lived Little mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Sir2 and calorie restriction in yeast: a skeptical perspective.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

The mitochondrial pathway in yeast apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

A signal from inside the peroxisome initiates its division by promoting the remodeling of the peroxisomal membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Counting calories in Drosophila diet restriction

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Uniqueness of the mechanism of protein import into the peroxisome matrix: transport of folded, co-factor-bound and oligomeric proteins by shuttling receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Calorie restriction mimetics: an emerging research field

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Apoptosis and lipoapoptosis in the fission yeast Schizosaccharomyces pombe.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

27 September 2017

Counting the calories: the role of specific nutrients in extension of life span by food restriction

1 reference

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27 September 2017

Toward a unified theory of caloric restriction and longevity regulation

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27 September 2017

Effect of a C/EBP gene replacement on mitochondrial biogenesis in fat cells.

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27 September 2017

Deletion of the intestinal peptide transporter affects insulin and TOR signaling in Caenorhabditis elegans

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27 September 2017

A quantitative assessment of the yeast lipidome using electrospray ionization mass spectrometry

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30 May 2018

TOR-driven aging: speeding car without brakes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

28 November 2018

Bile acids have the gall to function as hormones

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

28 November 2018

Effect of calorie restriction on the metabolic history of chronologically aging yeast

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

28 November 2018

Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

28 November 2018

Yeast Yak1 kinase, a bridge between PKA and stress-responsive transcription factors, Hsf1 and Msn2/Msn4.

1 reference

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28 November 2018

Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

28 November 2018

Gene expression profile of long-lived Ames dwarf mice and Little mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

28 November 2018

Nutritional control of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933888

28 November 2018

Long-lived dwarf mice: are bile acids a longevity signal?

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel function of lipid droplets in regulating longevity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20622262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/AGING.100168

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

release_cwavl45mlvcmtjf63o5layzhsa

1 reference

https://api.fatcat.wiki/v0/release/cwavl45mlvcmtjf63o5layzhsa

24 November 2022

based on heuristic

mapped directly with Wikidata item

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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