(Q24630061)

1

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Mark C Gebhard

2

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Qing Li

3

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Joseph M Taft

4

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George Georgiou

5

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Brent L Iverson

Proceedings of the National Academy of Sciences of the United States of America

6

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language of work or name

English

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publication date

30 April 2013

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published in

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volume

110

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issue

18

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page(s)

7229-34

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cites work

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In the light of directed evolution: pathways of adaptive protein evolution

7 April 2017

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Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidase

7 April 2017

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Structural basis for the substrate specificity of tobacco etch virus protease

7 April 2017

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ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway

7 April 2017

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Intracellular detection and evolution of site-specific proteases using a genetic selection system

7 April 2017

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Evolutionary optimization of peptide substrates for proteases that exhibit rapid hydrolysis kinetics

7 April 2017

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Protein engineering with bacterial display

7 April 2017

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Monitoring regulated protein-protein interactions using split TEV

7 April 2017

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Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency

7 April 2017

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Directed evolution of highly selective proteases by using a novel FACS-based screen that capitalizes on the p53 regulator MDM2

7 April 2017

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An overview of enzymatic reagents for the removal of affinity tags

27 September 2017

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Proteases as therapeutics

27 September 2017

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Emerging principles in protease-based drug discovery

27 September 2017

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Activation of specific apoptotic caspases with an engineered small-molecule-activated protease

27 September 2017

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Enzyme promiscuity: a mechanistic and evolutionary perspective

27 September 2017

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Proteases that can distinguish among different post-translational forms of tyrosine engineered using multicolor flow cytometry

27 September 2017

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Engineering next generation proteases

27 September 2017

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An engineered protease that cleaves specifically after sulfated tyrosine

27 September 2017

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Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

27 September 2017

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Highly active and selective endopeptidases with programmed substrate specificities

27 September 2017

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In search of partners: linking extracellular proteases to substrates

27 September 2017

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Diversification and specialization of HIV protease function during in vitro evolution

27 September 2017

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High-throughput screening of enzyme libraries: thiolactonases evolved by fluorescence-activated sorting of single cells in emulsion compartments.

27 September 2017

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Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity.

27 September 2017

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Directed evolution of the promiscuous esterase activity of carbonic anhydrase II.

27 September 2017

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Papa's got a brand new tag: advances in identification of proteases and their substrates

27 September 2017

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Critical amino acids in the active site of meprin metalloproteinases for substrate and peptide bond specificity

27 September 2017

1 reference

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Bacterial alkaline proteases: molecular approaches and industrial applications.

27 September 2017

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Design of high-throughput methods of protein production for structural biology

27 September 2017

1 reference

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Yeast surface display for screening combinatorial polypeptide libraries

27 September 2017

1 reference

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Biochemical and mutational analysis of a plant virus polyprotein cleavage site

27 September 2017

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Sorting of soluble ER proteins in yeast

27 September 2017

1 reference

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Basic and clinical aspects of fibrinolysis and thrombolysis

27 September 2017

1 reference

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Converting trypsin to chymotrypsin: the role of surface loops

27 September 2017

1 reference

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Engineering of protease variants exhibiting altered substrate specificity.

30 May 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1215994110