(Q24631189)

English

Downregulated kynurenine 3-monooxygenase gene expression and enzyme activity in schizophrenia and genetic association with schizophrenia endophenotypes

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scholarly article

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Europe PubMed Central

PubMed publication ID

21 June 2017

Downregulated kynurenine 3-monooxygenase gene expression and enzyme activity in schizophrenia and genetic association with schizophrenia endophenotypes (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

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1 reference

based on heuristic

inferred from title

Braxton D. Mitchell

5

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Europe PubMed Central

PubMed publication ID

21 June 2017

author name string

Ikwunga Wonodi

1

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Europe PubMed Central

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21 June 2017

O Colin Stine

2

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21 June 2017

Korrapati V Sathyasaikumar

3

1 reference

Europe PubMed Central

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21 June 2017

Rosalinda C Roberts

4

1 reference

Europe PubMed Central

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21 June 2017

L Elliot Hong

6

1 reference

Europe PubMed Central

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21 June 2017

Yasushi Kajii

7

1 reference

Europe PubMed Central

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21 June 2017

Gunvant K Thaker

8

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21 June 2017

Robert Schwarcz

9

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21 June 2017

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publication date

1 July 2011

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21 June 2017

JAMA Psychiatry

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21 June 2017

68

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Europe PubMed Central

PubMed publication ID

21 June 2017

7

1 reference

Europe PubMed Central

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21 June 2017

665-674

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

1 reference

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1 reference

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7 April 2017

Protein measurement with the Folin phenol reagent

1 reference

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Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia

1 reference

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The kynurenic acid hypothesis of schizophrenia

1 reference

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Intermediate phenotypes and genetic mechanisms of psychiatric disorders

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The endophenotype concept in psychiatry: etymology and strategic intentions

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The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications

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7 April 2017

Impaired kynurenine pathway metabolism in the prefrontal cortex of individuals with schizophrenia

1 reference

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27 September 2017

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Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in Schizophrenia

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27 September 2017

Prenatal infection and schizophrenia: a review of epidemiologic and translational studies

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27 September 2017

The 2009 schizophrenia PORT psychopharmacological treatment recommendations and summary statements

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Antipsychotic dose equivalents and dose-years: a standardized method for comparing exposure to different drugs.

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27 September 2017

The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex

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27 September 2017

Neonatal infection with neurotropic influenza A virus induces the kynurenine pathway in early life and disrupts sensorimotor gating in adult Tap1-/- mice

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27 September 2017

Smoking, Genetics and Schizophrenia: Evidence for Self Medication

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27 September 2017

Dopamine transporter polymorphism modulates oculomotor function and DAT1 mRNA expression in schizophrenia

1 reference

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27 September 2017

Kynurenine pathway and disease: an overview

1 reference

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27 September 2017

So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests

1 reference

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27 September 2017

Refining the predictive pursuit endophenotype in schizophrenia

1 reference

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27 September 2017

Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder

1 reference

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27 September 2017

Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission

1 reference

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27 September 2017

Elevations of endogenous kynurenic acid produce spatial working memory deficits

1 reference

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27 September 2017

Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population.

1 reference

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27 September 2017

Specific motion processing pathway deficit during eye tracking in schizophrenia: a performance-matched functional magnetic resonance imaging study

1 reference

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Chlorpromazine equivalent doses for the newer atypical antipsychotics

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27 September 2017

A model of smooth pursuit eye movement deficit associated with the schizophrenia phenotype

1 reference

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27 September 2017

Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities

1 reference

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27 September 2017

Predictive responses of periarcuate pursuit neurons to visual target motion

1 reference

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27 September 2017

Restriction of Toxoplasma gondii growth in human brain microvascular endothelial cells by activation of indoleamine 2,3-dioxygenase

1 reference

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27 September 2017

The emerging role of glutamate in the pathophysiology and treatment of schizophrenia

1 reference

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27 September 2017

Advances in schizophrenia

1 reference

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The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?

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Nicotine dependence in schizophrenia: clinical phenomena and laboratory findings

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27 September 2017

The glutamatergic dysfunction hypothesis for schizophrenia

1 reference

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27 September 2017

Neuropharmacology of quinolinic and kynurenic acids

1 reference

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27 September 2017

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

1 reference

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27 September 2017

Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia.

1 reference

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30 May 2018

Astrocyte-derived kynurenic acid modulates basal and evoked cortical acetylcholine release

1 reference

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30 May 2018

Efficient selection of tagging single-nucleotide polymorphisms in multiple populations.

1 reference

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30 May 2018

Using neurophysiological markers of genetic risk to define the boundaries of the schizophrenia spectrum phenotype.

1 reference

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30 May 2018

Increased cortical kynurenate content in schizophrenia

1 reference

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30 May 2018

Smooth pursuit eye movements to extraretinal motion signals: deficits in relatives of patients with schizophrenia.

1 reference

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30 May 2018

Neuronal responses related to smooth pursuit eye movements in the periarcuate cortical area of monkeys.

1 reference

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30 May 2018

Fast, anticipatory smooth-pursuit eye movements appear to depend on a short-term store.

1 reference

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30 May 2018

Confirmation of the diagnosis of schizophrenia after death using DSM-IV: a Victorian experience

1 reference

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30 May 2018

Synthesis and biochemical evaluation of N-(4-phenylthiazol-2-yl)benzenesulfonamides as high-affinity inhibitors of kynurenine 3-hydroxylase.

1 reference

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30 May 2018

Abnormal excitatory neurotransmitter metabolism in schizophrenic brains

1 reference

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30 May 2018

Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia

1 reference

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30 May 2018

An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid.

1 reference

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30 May 2018

Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: An association study

1 reference

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L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning.

1 reference

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28 November 2018

Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder

1 reference

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28 November 2018

Independent domains of inhibitory gating in schizophrenia and the effect of stimulus interval.

1 reference

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28 November 2018

Prepulse inhibition and P50 suppression are both deficient but not correlated in schizophrenia patients

1 reference

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28 November 2018

Critical factors in gene expression in postmortem human brain: Focus on studies in schizophrenia.

1 reference

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28 November 2018

Familial aggregation of eye-tracking endophenotypes in families of schizophrenic patients

1 reference

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28 November 2018

Upregulation of the initiating step of the kynurenine pathway in postmortem anterior cingulate cortex from individuals with schizophrenia and bipolar disorder

1 reference

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28 November 2018

Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia

1 reference

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Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers

1 reference

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28 November 2018

A concordance study of three electrophysiological measures in schizophrenia

1 reference

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28 November 2018

Lack of association between prepulse inhibition and antisaccadic deficits in chronic schizophrenia: implications for identification of schizophrenia endophenotypes

1 reference

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28 November 2018

Catechol O-methyltransferase polymorphism and eye tracking in schizophrenia: a preliminary report

1 reference

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28 November 2018

Endogenous kynurenic acid disrupts prepulse inhibition

1 reference

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28 November 2018

Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia

1 reference

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28 November 2018

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1 reference

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28 November 2018

Micromolar Brain Levels of Kynurenic Acid are Associated with a Disruption of Auditory Sensory Gating in the Rat

1 reference

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28 November 2018

Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia

1 reference

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28 November 2018

Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid

1 reference

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28 November 2018

Pursuit and saccadic eye movement subregions in human frontal eye field: a high-resolution fMRI investigation

1 reference

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28 November 2018

Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia

1 reference

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28 November 2018

Functional neuroanatomy of smooth pursuit and predictive saccades.

1 reference

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28 November 2018

Neural correlates of eye tracking deficits in first-degree relatives of schizophrenic patients: a positron emission tomography study.

1 reference

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28 November 2018

The effects of age on a smooth pursuit tracking task in adults with schizophrenia and normal subjects.

1 reference

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28 November 2018

Eye tracking abnormalities in schizophrenia: evidence for dysfunction in the frontal eye fields.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855543

28 November 2018

Neurobiology. Space and time in the mental universe.

1 reference

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28 November 2018

Neural responses related to smooth-pursuit eye movements and their correspondence with electrically elicited smooth eye movements in the primate frontal eye field.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855543

28 November 2018

Spatial working memory deficits in the relatives of schizophrenic patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855543

28 November 2018

Effects of optical isomers of ketamine on excitation of cat and rat spinal neurones by amino acids and acetylcholine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855543

28 November 2018

Eye-Tracking Patterns in Schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855543

28 November 2018

Identifiers

10.1001/ARCHGENPSYCHIATRY.2011.71

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

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