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Switching Akt: from survival signaling to deadly response
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title
Switching Akt: from survival signaling to deadly response
(English)
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author
Marek Łos
object named as
Marek Los
series ordinal
1
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author name string
Subbareddy Maddika
series ordinal
2
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Bettina Erb
series ordinal
3
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Klaus Schulze-Osthoff
series ordinal
4
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language of work or name
English
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publication date
May 2009
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published in
BioEssays
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volume
31
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issue
5
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page(s)
492-5
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cites work
No death without life: vital functions of apoptotic effectors
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PubMed Central
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AKT/PKB signaling: navigating downstream
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PubMed Central
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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
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7 April 2017
c-MYC: more than just a matter of life and death
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7 April 2017
Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase
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PubMed Central
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7 April 2017
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
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7 April 2017
PI3K pathway alterations in cancer: variations on a theme
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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
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7 April 2017
Unscheduled Akt-triggered activation of cyclin-dependent kinase 2 as a key effector mechanism of apoptin's anticancer toxicity.
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Drug discovery approaches targeting the PI3K/Akt pathway in cancer
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27 September 2017
Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis
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Repression of sestrin family genes contributes to oncogenic Ras-induced reactive oxygen species up-regulation and genetic instability
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The multiple battles fought by anti-apoptotic p21.
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27 September 2017
Only Akt1 is required for proliferation, while Akt2 promotes cell cycle exit through p21 binding.
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27 September 2017
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.
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27 September 2017
Identification of a tumour suppressor network opposing nuclear Akt function
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PubMed Central
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27 September 2017
Akt-dependent transformation: there is more to growth than just surviving
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27 September 2017
The Akt-mTOR tango and its relevance to cancer
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27 September 2017
Connecting proliferation and apoptosis in development and disease
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27 September 2017
Caspases: more than just killers?
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27 September 2017
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.
1 reference
stated in
PubMed Central
reference URL
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27 September 2017
Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954189
retrieved
30 May 2018
E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954189
retrieved
30 May 2018
Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species
1 reference
stated in
PubMed Central
reference URL
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retrieved
30 May 2018
Identifiers
DOI
10.1002/BIES.200900005
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
633405
OpenCitations bibliographic resource ID
633405
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
633405
PMC publication ID
2954189
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
633405
PubMed publication ID
19319914
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
633405
ResearchGate publication ID
24232806
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