(Q24632861)

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Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa

scientific article

Basis for the Specificity and Activation of the Serpin Protein Z-dependent Proteinase Inhibitor (ZPI) as an Inhibitor of Membrane-associated Factor Xa

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Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa (English)

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author name string

Xin Huang

1

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Alexey Dementiev

2

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Steven T Olson

3

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Peter G W Gettins

4

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language of work or name

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publication date

25 June 2010

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Journal of Biological Chemistry

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285

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26

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20399-409

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Crystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor X

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of alpha1-proteinase inhibitor with porcine pancreatic elastase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

Human Protein Z

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

Solving structures of protein complexes by molecular replacement with Phaser

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

On the size of the active site in proteases. I. Papain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

The protein Z-dependent protease inhibitor is a serpin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

Serpin structure, mechanism, and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

The coagulation cascade: initiation, maintenance, and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

7 April 2017

Exosite determinants of serpin specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

Protein Z-dependent protease inhibitor binds to the C-terminal domain of protein Z

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

Computational study of the putative active form of protein Z (PZa): sequence design and structural modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

Identification of factor Xa residues critical for interaction with protein Z-dependent protease inhibitor: both active site and exosite interactions are required for inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

Characterization of the protein Z-dependent protease inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

Isolation of a protein Z-dependent plasma protease inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

Conformational conversion of antithrombin to a fully activated substrate of factor Xa without need for heparin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

Comparison of naturally occurring vitamin K-dependent proteins: correlation of amino acid sequences and membrane binding properties suggests a membrane contact site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

Amino acid sequence of human protein Z, a vitamin K-dependent plasma glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

A novel one-step purification of human α-thrombin after direct activation of crude prothrombin enriched from plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

27 September 2017

Activation of antithrombin as a factor IXa and Xa inhibitor involves mitigation of repression rather than positive enhancement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

30 May 2018

Equilibria involved in prothrombin- and blood-clotting factor X-membrane binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888451

30 May 2018

Kinetic characterization of the protein Z-dependent protease inhibitor reaction with blood coagulation factor Xa.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.112748

21 January 2018

Alpha 1-proteinase inhibitor variant T345R. Influence of P14 residue on substrate and inhibitory pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.112748

21 January 2018

Serine and cysteine proteases are translocated to similar extents upon formation of covalent complexes with serpins. Fluorescence perturbation and fluorescence resonance energy transfer mapping of the protease binding site in CrmA complexes with gra

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.112748

21 January 2018

The pH dependence of serpin-proteinase complex dissociation reveals a mechanism of complex stabilization involving inactive and active conformational states of the proteinase which are perturbable by calcium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.112748

21 January 2018

Mapping of the catalytic groove preferences of factor Xa reveals an inadequate selectivity for its macromolecule substrates.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.112748

21 January 2018

Colorimetric determination of phospholipids with ammonium ferrothiocyanate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.112748

21 January 2018

Contributions of basic amino acids in the autolysis loop of factor XIa to serpin specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A proposed structural model of human protein Z

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Change in environment of the P1 side chain upon progression from the Michaelis complex to the covalent serpin-proteinase complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of proexosite I in factor Va-dependent substrate interactions of prothrombin activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction pathway for inhibition of blood coagulation factor Xa by tick anticoagulant peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerating ability of synthetic oligosaccharides on antithrombin inhibition of proteinases of the clotting and fibrinolytic systems. Comparison with heparin and low-molecular-weight heparin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of basic residues in the heparin-binding exosite of factor Xa critical for heparin and factor Va binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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