(Q24633423)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21099112%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice (English)

1 reference

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16 January 2020

1 reference

5

1 reference

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16 January 2020

Nancy Andrews

10

1 reference

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16 January 2020

Antonia Follenzi

12

1 reference

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16 January 2020

Stefano Rivella

19

1 reference

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16 January 2020

17

Patricia J Giardina

1 reference

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16 January 2020

1

Sara Gardenghi

1 reference

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16 January 2020

4

Luca Melchiori

1 reference

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16 January 2020

6

Ella Guy

1 reference

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16 January 2020

author name string

Pedro Ramos

2

1 reference

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16 January 2020

Maria Franca Marongiu

3

1 reference

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16 January 2020

Kristen Muirhead

7

1 reference

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16 January 2020

Niva Rao

8

1 reference

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16 January 2020

Cindy N Roy

9

1 reference

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16 January 2020

Elizabeta Nemeth

11

1 reference

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16 January 2020

Yelena Ginzburg

15

1 reference

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16 January 2020

Eliezer A Rachmilewitz

16

1 reference

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16 January 2020

Robert W Grady

18

1 reference

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16 January 2020

Xiuli An

13

1 reference

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16 January 2020

Narla Mohandas

14

1 reference

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16 January 2020

language of work or name

English

0 references

publication date

22 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21099112%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

16 January 2020

published in

1 reference

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16 January 2020

volume

120

1 reference

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16 January 2020

issue

12

1 reference

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16 January 2020

page(s)

4466-4477

1 reference

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describes a project that uses

16 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2993583/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Ineffective erythropoiesis and thalassemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Identification of a human heme exporter that is essential for erythropoiesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Loss of alpha-hemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

A heme export protein is required for red blood cell differentiation and iron homeostasis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

A mouse model for beta 0-thalassemia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Regulation of iron absorption in hemoglobinopathies.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Regulation of protein synthesis by the heme-regulated eIF2alpha kinase: relevance to anemias

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Survival and complications in thalassemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Hepcidin in iron overload disorders

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

The role of membrane skeletal-associated alpha-globin in the pathophysiology of beta-thalassemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Iron absorption and loading in beta-thalassaemia intermedia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Mechanism of Desferrioxamine-Induced Iron Excretion in Thalassaemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Transferrin therapy ameliorates disease in beta-thalassemic mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Liver expression of hepcidin and other iron genes in two mouse models of beta-thalassemia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993583

Kinetics of removal and reappearance of non-transferrin-bound plasma iron with deferoxamine therapy

28 November 2018

1 reference

12 December 2020

mRNA expression of iron regulatory genes in β-thalassemia intermedia and β-thalassemia major mouse models

1 reference

12 December 2020

Absorption of inorganic and food iron in children with heterozygous and homozygous ?-thalassemia

1 reference

12 December 2020

A mouse model for β-thalassemia

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI41717

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21099112%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21099112%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

2 references