Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q24646412)
Watch
English
E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
title
E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
main subject
apoptotic process
0 references
DNA damage
0 references
author
Shweta Tyagi
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
Winship Herr
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
author name string
Shweta Tyagi
series ordinal
1
0 references
Winship Herr
series ordinal
2
0 references
language of work or name
English
0 references
publication date
17 September 2009
1 reference
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
published in
The EMBO Journal
1 reference
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
volume
28
1 reference
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
page(s)
3185-3195
1 reference
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
issue
20
1 reference
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
cites work
MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
E2F transcriptional activation requires TRRAP and GCN5 cofactors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
TIP49, but not TRRAP, modulates c-Myc and E2F1 dependent apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
Sibling rivalry in the E2F family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
7 April 2017
p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
10 May 2017
An oncogene-induced DNA damage model for cancer development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
DNA damage signalling guards against activated oncogenes and tumour progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
E2F-associated chromatin modifiers and cell cycle control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
Host cell factor-1 and E2F4 interact via multiple determinants in each protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
Jab1 is a specificity factor for E2F1-induced apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
MLL: a histone methyltransferase disrupted in leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
The herpes simplex virus VP16-induced complex: the makings of a regulatory switch
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
Proteolytic processing is necessary to separate and ensure proper cell growth and cytokinesis functions of HCF-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
Role of the p53-homologue p73 in E2F1-induced apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
Role for the p53 homologue p73 in E2F-1-induced apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
A single-point mutation in HCF causes temperature-sensitive cell-cycle arrest and disrupts VP16 function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
27 September 2017
Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
30 May 2018
p14ARF links the tumour suppressors RB and p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
19 June 2018
Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
28 July 2018
E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
28 November 2018
E2F1 is crucial for E2F-dependent apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
28 November 2018
E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
28 November 2018
Apaf-1 is a transcriptional target for E2F and p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771094
retrieved
28 November 2018
Identifiers
DOI
10.1038/EMBOJ.2009.258
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1110497
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
OpenCitations bibliographic resource ID
1110497
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1110497
PMCID
2771094
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1110497
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
PubMed ID
19763085
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1110497
stated in
Europe PubMed Central
PMCID
2771094
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19763085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
ResearchGate publication ID
26820665
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit