(Q24652819)

1

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Gözde Ulas

2

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Jaeyoung Song

3

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William Furey

5

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Frank Jordan

Proceedings of the National Academy of Sciences of the United States of America

6

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language of work or name

English

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publication date

29 January 2008

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published in

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volume

105

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issue

4

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page(s)

1158-63

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cites work

A dynamic loop at the active center of the Escherichia coli pyruvate dehydrogenase complex E1 component modulates substrate utilization and chemical communication with the E2 component

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Antibody multispecificity mediated by conformational diversity

7 April 2017

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Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A resolution

7 April 2017

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Solution-state NMR investigations of triosephosphate isomerase active site loop motion: ligand release in relation to active site loop dynamics

7 April 2017

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Electrostatic basis for enzyme catalysis

7 April 2017

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Molecular recognition via coupled folding and binding in a TPR domain

7 April 2017

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Intrinsic dynamics of an enzyme underlies catalysis

7 April 2017

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Coupling of local folding to site-specific binding of proteins to DNA

7 April 2017

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Binding induced conformational changes of proteins correlate with their intrinsic fluctuations: a case study of antibodies

7 April 2017

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The 1',4'-iminopyrimidine tautomer of thiamin diphosphate is poised for catalysis in asymmetric active centers on enzymes

28 September 2017

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Dynamically driven protein allostery.

28 September 2017

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New tools provide new insights in NMR studies of protein dynamics

28 September 2017

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Probing the binding entropy of ligand-protein interactions by NMR.

28 September 2017

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Glutamate 636 of the Escherichia coli pyruvate dehydrogenase-E1 participates in active center communication and behaves as an engineered acetolactate synthase with unusual stereoselectivity

28 September 2017

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The tandem Src homology 2 domain of the Syk kinase: a molecular device that adapts to interphosphotyrosine distances

28 September 2017

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Impact of enzyme motion on activity

28 September 2017

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Dynamic activation of protein function: a view emerging from NMR spectroscopy.

28 September 2017

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Inhibition of the Escherichia coli pyruvate dehydrogenase complex E1 subunit and its tyrosine 177 variants by thiamin 2-thiazolone and thiamin 2-thiothiazolone diphosphates. Evidence for reversible tight-binding inhibition

28 September 2017

1 reference

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Manipulation of ligand binding affinity by exploitation of conformational coupling

28 September 2017

1 reference

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Binding sites in Escherichia coli dihydrofolate reductase communicate by modulating the conformational ensemble

28 September 2017

1 reference

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Redistribution and loss of side chain entropy upon formation of a calmodulin-peptide complex

28 September 2017

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The structural basis of negative cooperativity: receptors and enzymes

28 September 2017

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Amino-terminal residues 1-45 of the Escherichia coli pyruvate dehydrogenase complex E1 subunit interact with the E2 subunit and are required for activity of the complex but not for reductive acetylation of the E2 subunit

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234108

2-Oxo-3-alkynoic acids, universal mechanism-based inactivators of thiamin diphosphate-dependent decarboxylases: synthesis and evidence for potent inactivation of the pyruvate dehydrogenase multienzyme complex.

30 May 2018

1 reference

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A thiamin-bound, pre-decarboxylation reaction intermediate analogue in the pyruvate dehydrogenase E1 subunit induces large scale disorder-to-order transformations in the enzyme and reveals novel structural features in the covalently bound adduct

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709328105

Tetrahedral intermediates in thiamin diphosphate-dependent decarboxylations exist as a 1',4'-imino tautomeric form of the coenzyme, unlike the michaelis complex or the free coenzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709328105

Histidine 407, a phantom residue in the E1 subunit of the Escherichia coli pyruvate dehydrogenase complex, activates reductive acetylation of lipoamide on the E2 subunit. An explanation for conservation of active sites between the E1 subunit and tra

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709328105

NMR analysis of covalent intermediates in thiamin diphosphate enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709328105

Delineation of the allosteric mechanism of a cytidylyltransferase exhibiting negative cooperativity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709328105

An increase in side chain entropy facilitates effector binding: NMR characterization of the side chain methyl group dynamics in Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709328105

Thermodynamic Study of the Binding of the Tandem-SH2 Domain of the Syk Kinase to a Dually Phosphorylated ITAM Peptide: Evidence for Two Conformers†

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709328105

Disorder-order folding transitions underlie catalysis in the helicase motor of SecA

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709328105

Enzyme dynamics during catalysis measured by NMR spectroscopy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234108

Elucidation of the chemistry of enzyme-bound thiamin diphosphate prior to substrate binding: defining internal equilibria among tautomeric and ionization states

28 November 2018

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12 December 2020

NMR characterization of the dynamics of biomacromolecules

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12 December 2020

Allostery without conformational change. A plausible model

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12 December 2020

Allosteric properties of inosine monophosphate dehydrogenase revealed through the thermodynamics of binding of inosine 5'-monophosphate and mycophenolic acid. Temperature dependent heat capacity of binding as a signature of ligand-coupled conformati

1 reference

12 December 2020

Systematic study of the six cysteines of the E1 subunit of the pyruvate dehydrogenase multienzyme complex from Escherichia coli: none is essential for activity

1 reference

12 December 2020

alpha-Keto acid dehydrogenation complexes. I. Purification and properties of pyruvate and alpha-ketoglutarate dehydrogenation complexes of Escherichia coli

1 reference

12 December 2020

Nonlinear-Least-Squares Analysis of Slow-Motion EPR Spectra in One and Two Dimensions Using a Modified Levenberg–Marquardt Algorithm

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709328105

7 January 2021