(Q24658454)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19025129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

1 reference

title

Compstatin: a complement inhibitor on its way to clinical application (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19025129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19025129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

John D. Lambris

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19025129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Daniel Ricklin

series ordinal

1

0 references

John D Lambris

series ordinal

2

0 references

language of work or name

English

0 references

publication date

1 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19025129%20AND%20SRC:MED&resulttype=core&format=json

Advances in Experimental Medicine and Biology

17 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19025129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

632

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19025129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

273-292

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19025129%20AND%20SRC:MED&resulttype=core&format=json

Solution structure of Compstatin, a potent complement inhibitor

17 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Characterization of Ehp, a secreted complement inhibitory protein from Staphylococcus aureus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

A structural basis for complement inhibition by Staphylococcus aureus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Structure of C3b reveals conformational changes that underlie complement activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Structure of C3b in complex with CRIg gives insights into regulation of complement activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Complement evasion by human pathogens

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Complement-targeted therapeutics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Staphylococcal complement evasion by various convertase-blocking molecules.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Exploring the complement interaction network using surface plasmon resonance.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

The role of complement system in ocular diseases including uveitis and macular degeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

The role of complement in inflammatory diseases from behind the scenes into the spotlight

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

CD59 efficiently protects human NT2-N neurons against complement-mediated damage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

New perspectives on mannan-binding lectin-mediated complement activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Conformational analysis of compstatin analogues with molecular dynamics simulations in explicit water

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

New therapeutic targets in atrophic age-related macular degeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

A simple, yet highly accurate, QSAR model captures the complement inhibitory activity of compstatin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Mechanism of angioedema in first complement component inhibitor deficiency

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Therapeutic peptides: technological advances driving peptides into development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

The role of complement in biomaterial-induced inflammation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Structural insights into the central complement component C3.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Natural polypeptide scaffolds: beta-sheets, beta-turns, and beta-hairpins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Synthetic small-molecule complement inhibitors.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Phage display-derived peptides as therapeutic alternatives to antibodies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Improvement of the anti-C3 activity of compstatin using rational and combinatorial approaches

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Studies of structure-activity relations of complement inhibitor compstatin.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Design of beta-turn based therapeutic agents

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Structural aspects and design of low-molecular-mass complement inhibitors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Screening phage-displayed combinatorial peptide libraries

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

C3 activation is inhibited by analogs of compstatin but not by serine protease inhibitors or peptidyl alpha-ketoheterocycles

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Inhibition of herpes simplex virus gD and lymphotoxin-alpha binding to HveA by peptide antagonists.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Binding kinetics, structure-activity relationship, and biotransformation of the complement inhibitor compstatin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Structure, functions, and evolution of the third complement component and viral molecular mimicry

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Evidence for complement activation by protamine-heparin interaction after cardiopulmonary bypass

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Compstatin inhibits complement activation by binding to the beta-chain of complement factor 3.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Expression of compstatin in Escherichia coli: incorporation of unnatural amino acids enhances its activity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Development of a quasi-dynamic pharmacophore model for anti-complement peptide analogues

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Design and NMR characterization of active analogues of compstatin containing non-natural amino acids

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Effect of complement inhibition and heparin coating on artificial surface-induced leukocyte and platelet activation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Conformational interconversion in compstatin probed with molecular dynamics simulations

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700864

Hydrophobic Effect and Hydrogen Bonds Account for the Improved Activity of a Complement Inhibitor, Compstatin

28 November 2018

1 reference

12 December 2020

Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement

1 reference

12 December 2020

Immune complex-stimulated production of interleukin-12 in peripheral blood mononuclear cells is regulated by the complement system

1 reference

12 December 2020

Affinity maturation of phage-displayed peptide ligands

1 reference

12 December 2020

Inhibition of Heparin/Protamine Complex-Induced Complement Activation by Compstatin in Baboons

1 reference

12 December 2020

Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated

1 reference

12 December 2020

Effects of C-reactive protein and pentosan polysulphate on human complement activation

1 reference

12 December 2020

Integrated Computational and Experimental Approach for Lead Optimization and Design of Compstatin Variants with Improved Activity

1 reference

12 December 2020

Inhibitor of complement, Compstatin, prevents polymer-mediated Mac-1 up-regulation of human neutrophils independent of biomaterial type tested

1 reference

12 December 2020

Compstatin inhibits complement and cellular activation in whole blood in two models of extracorporeal circulation

1 reference

12 December 2020

Prolongation of ex vivo–perfused pig xenograft survival by the complement inhibitor compstatin

1 reference

12 December 2020

Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts

1 reference

12 December 2020

Binding of C3 fragments on top of adsorbed plasma proteins during complement activation on a model biomaterial surface

1 reference

12 December 2020

Understanding the structural characteristics of compstatin by conformational space annealing

1 reference

12 December 2020

Roles of group IIA phospholipase A2 and complement in killing of bacteria by acute phase serum

1 reference

12 December 2020

10.1007/978-0-387-78952-1_20

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19025129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19025129%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference