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Molecular targets underlying general anaesthesia
scientific article
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instance of
scholarly article
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review article
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stated in
Europe PubMed Central
title
Molecular targets underlying general anaesthesia
(English)
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main subject
general anaesthesia
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based on heuristic
inferred from title
author
Nicholas Franks
object named as
Nicholas P Franks
series ordinal
1
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language of work or name
English
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publication date
January 2006
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published in
British Journal of Pharmacology
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volume
147 Suppl 1
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issue
S1
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page(s)
S72-81
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cites work
Binding of the general anesthetics propofol and halothane to human serum albumin. High resolution crystal structures
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PubMed Central
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The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid
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Stereoselective effects of etomidate optical isomers on gamma-aminobutyric acid type A receptors and animals
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HCN subunit-specific and cAMP-modulated effects of anesthetics on neuronal pacemaker currents.
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28 September 2017
TREK-1, a K+ channel involved in neuroprotection and general anesthesia
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PubMed Central
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28 September 2017
Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration
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28 September 2017
Mechanisms of actions of inhaled anesthetics
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28 September 2017
Volatile anesthetic actions on the GABAA receptors: contrasting effects of alpha 1(S270) and beta 2(N265) point mutations
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28 September 2017
Molecular determinants for the action of general anesthetics at recombinant alpha(2)beta(3)gamma(2)gamma-aminobutyric acid(A) receptors.
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Anesthetic-sensitive 2P domain K+ channels.
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PubMed Central
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28 September 2017
Evidence for a common binding cavity for three general anesthetics within the GABAA receptor.
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The TASK-1 two-pore domain K+ channel is a molecular substrate for neuronal effects of inhalation anesthetics.
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28 September 2017
Specific binding sites for alcohols and anesthetics on ligand-gated ion channels
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28 September 2017
Enhancement of homomeric glycine receptor function by long-chain alcohols and anaesthetics
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PubMed Central
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28 September 2017
Effects of inhalational general anaesthetics on native glycine receptors in rat medullary neurones and recombinant glycine receptors in Xenopus oocytes
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PubMed Central
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28 September 2017
Molecular and cellular mechanisms of general anaesthesia
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PubMed Central
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28 September 2017
Molecular mechanisms of general anaesthesia
1 reference
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PubMed Central
reference URL
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28 September 2017
Do general anaesthetics act by competitive binding to specific receptors?
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PubMed Central
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28 September 2017
Barbiturate receptor sites are coupled to benzodiazepine receptors
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PubMed Central
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28 September 2017
The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones
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PubMed Central
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28 September 2017
Different Actions of Anticonvulsant and Anesthetic Barbiturates Revealed by Use of Cultured Mammalian Neurons
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PubMed Central
reference URL
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28 September 2017
Pentobarbital: Differential Postsynaptic Actions on Sympathetic Ganglion Cells
1 reference
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PubMed Central
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28 September 2017
Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.
1 reference
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PubMed Central
reference URL
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retrieved
30 May 2018
Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
retrieved
30 May 2018
Positive modulation of human gamma-aminobutyric acid type A and glycine receptors by the inhalation anesthetic isoflurane
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
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30 May 2018
Facilitatory action of etomidate and pentobarbital on recurrent inhibition in rat hippocampal pyramidal neurons
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
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30 May 2018
Volatile general anaesthetics activate a novel neuronal K+ current
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
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30 May 2018
A hypnotic response to dexmedetomidine, an alpha 2 agonist, is mediated in the locus coeruleus in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
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30 May 2018
Isoflurane-induced surgical tolerance mediated only in part by beta3-containing GABA(A) receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
retrieved
28 November 2018
Isoflurane inhibits transmitter release and the presynaptic action potential
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
retrieved
28 November 2018
Defining the propofol binding site location on the GABAA receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
retrieved
28 November 2018
2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
retrieved
28 November 2018
General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
retrieved
28 November 2018
The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
retrieved
28 November 2018
Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760740
retrieved
28 November 2018
Identifiers
DOI
10.1038/SJ.BJP.0706441
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4228267
OpenCitations bibliographic resource ID
4228267
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4228267
PMC publication ID
1760740
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4228267
PubMed publication ID
16402123
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4228267
ResearchGate publication ID
7370003
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