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A GFP-based reporter system to monitor nonsense-mediated mRNA decay
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title
A GFP-based reporter system to monitor nonsense-mediated mRNA decay
(English)
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author
Oliver Mühlemann
series ordinal
5
object named as
Oliver Mühlemann
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author name string
Alexandra Paillusson
series ordinal
1
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Nadine Hirschi
series ordinal
2
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Claudio Vallan
series ordinal
3
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Claus M Azzalin
series ordinal
4
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language of work or name
English
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publication date
2005
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published in
Nucleic Acids Research
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volume
33
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page(s)
e54
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issue
6
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cites work
An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay
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Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways
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Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.
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7 April 2017
Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1
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7 April 2017
Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay
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Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon
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Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)
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Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes
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Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein
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7 April 2017
Mammalian orthologues of a yeast regulator of nonsense transcript stability
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A system for stable expression of short interfering RNAs in mammalian cells
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A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed
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7 April 2017
Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics
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7 April 2017
Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans
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7 April 2017
A genomic view of alternative splicing
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7 April 2017
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
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7 April 2017
Nonsense-mediated mRNA decay in health and disease
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7 April 2017
Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease
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7 April 2017
The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon
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7 April 2017
Nonsense-mediated decay approaches the clinic
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28 September 2017
Efficient downregulation of immunoglobulin mu mRNA with premature translation-termination codons requires the 5'-half of the VDJ exon
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28 September 2017
eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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28 September 2017
T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts
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28 September 2017
Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements
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28 September 2017
When the message goes awry: disease-producing mutations that influence mRNA content and performance.
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28 September 2017
The Y14 protein communicates to the cytoplasm the position of exon-exon junctions
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28 September 2017
Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability
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28 September 2017
Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin-3 mRNA degradation pathway.
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28 September 2017
smg-7 is required for mRNA surveillance in Caenorhabditis elegans.
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28 September 2017
A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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28 September 2017
A splicing-dependent regulatory mechanism that detects translation signals
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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28 September 2017
Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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28 September 2017
Nonsense mutations in the human beta-globin gene affect mRNA metabolism
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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28 September 2017
Translation to near the distal end of the penultimate exon is required for normal levels of spliced triosephosphate isomerase mRNA.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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28 September 2017
High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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28 September 2017
Gene products that promote mRNA turnover in Saccharomyces cerevisiae
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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28 September 2017
A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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28 September 2017
Binary specification of nonsense codons by splicing and cytoplasmic translation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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30 May 2018
Nonsense surveillance in lymphocytes?
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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30 May 2018
Precursor RNAs harboring nonsense codons accumulate near the site of transcription.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1072805
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28 November 2018
mRNA surveillance by the Caenorhabditis elegans smg genes
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15800205
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/NAR/GNI052
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PMCID
1072805
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PubMed ID
15800205
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ResearchGate publication ID
7936226
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