(Q24810933)

English

Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

0 references

0 references

histone acetylation

1 reference

based on heuristic

inferred from title

cervix uterine cancer

1 reference

based on heuristic

inferred from title

Carlos Pérez-Plasencia

1 reference

ORCID Public Data File 2021

author name string

Alma Chavez-Blanco

1

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Blanca Segura-Pacheco

2

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Enrique Perez-Cardenas

3

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Lucia Taja-Chayeb

4

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Lucely Cetina

5

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Myrna Candelaria

6

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

David Cantu

7

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Aurora Gonzalez-Fierro

8

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Patricia Garcia-Lopez

9

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Pilar Zambrano

10

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Carlos Perez-Plasencia

11

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Gustavo Cabrera

12

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Catalina Trejo-Becerril

13

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Enrique Angeles

14

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Alfonso Duenas-Gonzalez

15

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

language of work or name

0 references

publication date

7 July 2005

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Molecular Cancer

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

7 April 2017

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

7 April 2017

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

7 April 2017

Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

7 April 2017

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

7 April 2017

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

7 April 2017

Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Role of histone deacetylase inhibitors in the treatment of cancer (Review).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Phase I trial design for solid tumor studies of targeted, non-cytotoxic agents: theory and practice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Antiepileptic drugs inhibit cell growth in the human breast cancer cell line MCF7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Targeted histone deacetylase inhibition for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Triple analysis of the cancer epigenome: an integrated microarray system for assessing gene expression, DNA methylation, and histone acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Novel endpoints and design of early clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Induction of differentiation and suppression of malignant phenotype of human neuroblastoma BE(2)-C cells by valproic acid: enhancement by combination with interferon-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Multicenter case series of valproic acid ingestion: serum concentrations and toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Valproic acid for the treatment of pediatric malignant glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Valproic acid. A reappraisal of its pharmacological properties and clinical efficacy in epilepsy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Steady-state kinetics of valproic acid in epileptic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 September 2017

Valproic acid and interferon-alpha synergistically inhibit neuroblastoma cell growth in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 November 2018

Susceptibility and radiosensitization of human glioblastoma cells to trichostatin A, a histone deacetylase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 November 2018

Histone deacetylase is a target of valproic acid-mediated cellular differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 November 2018

Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 November 2018

Susceptibility of multidrug resistance tumor cells to apoptosis induction by histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 November 2018

Valproic acid induces apoptosis in human leukemia cells by stimulating both caspase-dependent and -independent apoptotic signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 November 2018

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 November 2018

Different effects of valproic acid on proliferation and migration of malignant glioma cells in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 November 2018

DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1198251

28 November 2018

Epigenetics and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16001982

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose escalation trial designs based on a molecularly targeted endpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/16001982

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumors: a clinical and translational study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16001982

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nontoxicity endpoints in phase I trial designs for targeted, non-cytotoxic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/16001982

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorescence Polarization Immunoassay for the Determination of Therapeutic Drug Levels in Human Plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16001982

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single dose and steady state pharmacokinetics of valproic acid in adult epileptic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16001982

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between serum concentration and dose of valproic acid during monotherapy in adult outpatients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16001982

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1476-4598-4-22

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

ResearchGate publication ID

0 references

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