(Q24814949)

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Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: implications for replication of telomeric DNA

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Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: implications for replication of telomeric DNA (English)

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Saccharomyces cerevisiae

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MRX complex nuclease subunit YMR224C

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GOA release 2020-03-11

Kalappa Muniyappa

2

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K Muniyappa

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author name string

Gargi Ghosal

1

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language of work or name

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publication date

2005

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Nucleic Acids Research

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33

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15

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4692-703

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How do site-specific DNA-binding proteins find their targets?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Crystal structure of parallel quadruplexes from human telomeric DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Yeast Xrs2 Binds DNA and Helps Target Rad50 and Mre11 to DNA Ends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Cdc13 delivers separate complexes to the telomere for end protection and replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

The yeast telomere-binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

A mutant with a defect in telomere elongation leads to senescence in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Human Rad50/Mre11 is a flexible complex that can tether DNA ends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Regulation of telomerase by telomeric proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Switching and signaling at the telomere

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

An alternative pathway for yeast telomere maintenance rescues est1- senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

7 April 2017

Taz1 binding to a fission yeast model telomere: formation of telomeric loops and higher order structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

MRE11/RAD50/NBS1: complex activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

Helix formation by guanylic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

Telomere maintenance and DNA replication: how closely are these two connected?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

V(D)J recombination: RAG proteins, repair factors, and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

A human nuclease specific for G4 DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

t-loops at trypanosome telomeres.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

A mechanistic basis for Mre11-directed DNA joining at microhomologies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

The Mre11 complex and ATM: collaborating to navigate S phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

Yeast meiosis-specific protein Hop1 binds to G4 DNA and promotes its formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

Telomeres and telomerase: at the end, it all comes together

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

Porphyrin binding to quadrupled T4G4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

DNA-binding activities of Hop1 protein, a synaptonemal complex component from Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

Promotion of parallel DNA quadruplexes by a yeast telomere binding protein: a circular dichroism study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

G-quartet structures in telomeric DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

Inhibition of telomerase by G-quartet DNA structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 September 2017

Association of Mre11p with double-strand break sites during yeast meiosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 November 2018

Telomere dysfunction increases mutation rate and genomic instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 November 2018

Telomere maintenance is dependent on activities required for end repair of double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1188515

28 November 2018

The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements

1 reference

https://pubmed.ncbi.nlm.nih.gov/16116037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The many interfaces of Mre11

1 reference

https://pubmed.ncbi.nlm.nih.gov/16116037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A sodium-potassium switch in the formation of four-stranded G4-DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/16116037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The yeast KEM1 gene encodes a nuclease specific for G4 tetraplex DNA: implication of in vivo functions for this novel DNA structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/16116037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process

1 reference

https://pubmed.ncbi.nlm.nih.gov/16116037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the Mre11-Rad50-Xrs2 complex in telomerase- mediated lengthening of Saccharomyces cerevisiae telomeres

1 reference

https://pubmed.ncbi.nlm.nih.gov/16116037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere

1 reference

https://pubmed.ncbi.nlm.nih.gov/16116037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of telomeric sequences and senescence caused by mutations in RAD50 of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/16116037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GKI777

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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