(Q25326660)

Niraparib (English)

19 October 2016

C₁₉H₂₀N₄O

1 reference

Niraparib (English)

19 October 2016

C1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N

1 reference

Niraparib (English)

19 October 2016

NC(=O)C1=CC=CC2=CN(N=C12)C3=CC=C(C=C3)[C@@H]4CCCNC4

1 reference

medical condition treated

14 February 2018

1 reference

14 February 2018

peritoneum cancer

1 reference

Drug Indications Extracted from FAERS

2 October 2018

fallopian tube carcinoma

1 reference

Drug Indications Extracted from FAERS

2 October 2018

26 March 2017

Food and Drug Administration

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/HMC2H89N35

2 November 2018

reference URL

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208447lbl.pdf

physically interacts with

Poly(ADP-ribose) polymerase 2

subject has role

reaction inhibitor

1 reference

Open Targets Platform

https://platform.opentargets.org/drug/CHEMBL1094636

14 August 2023

reference URL

LiverTox likelihood score

LiverTox toxicity likelihood category E*

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Niraparib

20 July 2017

1 reference

Medical Subject Headings

15 March 2018

C80059

1 reference

InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1

14 February 2018

Niraparib

0 references

Identifiers

InChI

1 reference

PCHKPVIQAHNQLW-CQSZACIVSA-N

Niraparib (English)

19 October 2016

2 references

Niraparib (English)

19 October 2016

14 February 2018

2 references

PCHKPVIQAHNQLW-CQSZACIVSA-N

14 February 2018

8 April 2021

https://commonchemistry.cas.org/detail?cas_rn=1038915-60-4

1 reference

Niraparib (English)

19 October 2016

1 reference

Niraparib (English)

19 October 2016

mapping relation type

exact match

1 reference

ChEBI release 2022-06-13

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

NIRAPARIB (English)

19 October 2016

1 reference

1 reference

DSSTOX compound identifier

0 references

0 references

685-112-3

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.210.548

ECHA Substance Infocard ID

27 December 2018

title

[Name confidential or not available] (English)

quotation

CAS no.: 1038915-60-4 (English)

100.210.548

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.210.548

Guide to Pharmacology Ligand ID

20 December 2018

title

[Name confidential or not available] (English)

quotation

CAS no.: 1038915-60-4 (English)

ATC code

L01XX54

0 references

8275

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

8275

niraparib (English)

19 October 2016

1 reference

Medical Subject Headings

14 March 2018

1 reference

14 February 2018

1 reference

Niraparib (English)

3 July 2018

1 reference

UNII

HMC2H89N35

MedlinePlus drug identifier

14 February 2018

0 references

1 reference

26 February 2018

0 references

1 reference

0 references

Google Knowledge Graph ID

0 references

1 reference

English

title

4R6E (English)