(Q26738467)

title

Antibodies inside of a cell can change its outside: Can intrabodies provide a new therapeutic paradigm? (English)

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27570612%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Stefan Dübel

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27570612%20AND%20SRC:MED&resulttype=core&format=json

Computational and Structural Biotechnology Journal

13 June 2020

author name string

Andrea L J Marschall

series ordinal

1

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language of work or name

English

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publication date

2016

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published in

2 references

Crossref

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27570612%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27570612%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

304-308

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27570612%20AND%20SRC:MED&resulttype=core&format=json

Protein production and purification

13 June 2020

cites work

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7 April 2017

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Specific in vivo knockdown of protein function by intrabodies

7 April 2017

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Adeno-associated virus at 50: a golden anniversary of discovery, research, and gene therapy success--a personal perspective

7 April 2017

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7 April 2017

Gene therapy on the move

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Genome editing. The new frontier of genome engineering with CRISPR-Cas9

7 April 2017

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A roadmap to generate renewable protein binders to the human proteome

7 April 2017

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Suppression of p75 neurotrophin receptor surface expression with intrabodies influences Bcl-xL mRNA expression and neurite outgrowth in PC12 cells

7 April 2017

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Single Chain Antibodies as Tools to Study transforming growth factor-β-Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens

7 April 2017

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Single-domain intrabodies against hepatitis C virus core inhibit viral propagation and core-induced NFκB activation

28 September 2017

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A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16-positive tumor cells in mouse models

28 September 2017

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Growth signalobody selects functional intrabodies in the mammalian cytoplasm

28 September 2017

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Intrabody-mediated diverting of HP1β to the cytoplasm induces co-aggregation of H3-H4 histones and lamin-B receptor

28 September 2017

1 reference

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Selection of human single domain antibodies recognizing the CMYC protein using enhanced intracellular antibody capture.

28 September 2017

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Engineering the AAV capsid to optimize vector-host-interactions

28 September 2017

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The translocon protein Sec61 mediates antigen transport from endosomes in the cytosol for cross-presentation to CD8(+) T cells

28 September 2017

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Generation and analysis of the improved human HAL9/10 antibody phage display libraries

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Functional knock down of VCAM1 in mice mediated by endoplasmatic reticulum retained intrabodies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Delivery of antibodies to the cytosol: debunking the myths

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Single chain variable fragment antibodies block aggregation and toxicity induced by familial ALS-linked mutant forms of SOD1.

28 September 2017

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Intracellular antibody capture (IAC) methods for single domain antibodies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

In vivo selection of CD4(+) T cells transduced with a gamma-retroviral vector expressing a single-chain intrabody targeting HIV-1 tat.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Engineered antibody therapies to counteract mutant huntingtin and related toxic intracellular proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Targeting antibodies to the cytoplasm

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Abeta-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Towards proteome scale antibody selections using phage display

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Delivery of macromolecules using arginine-rich cell-penetrating peptides: ways to overcome endosomal entrapment.

28 September 2017

1 reference

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Efficient isolation of soluble intracellular single-chain antibodies using the twin-arginine translocation machinery

28 September 2017

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In vivo selection of intrabodies specifically targeting protein-protein interactions: a general platform for an "undruggable" class of disease targets

28 September 2017

1 reference

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Intracellular antibodies (intrabodies) and their therapeutic potential

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery.

28 September 2017

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A universal strategy for stable intracellular antibodies

28 September 2017

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Intrabodies as drug discovery tools and therapeutics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Phenotypic knockout of VEGF-R2 and Tie-2 with an intradiabody reduces tumor growth and angiogenesis in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

A human single-chain Fv intrabody blocks aberrant cellular effects of overexpressed alpha-synuclein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Antigen-independent selection of intracellular stable antibody frameworks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Evaluation of strategies for the intracellular delivery of proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

The intracellular antibody capture technology (IACT): towards a consensus sequence for intracellular antibodies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

10-nm filaments are induced to collapse in living cells microinjected with monoclonal and polyclonal antibodies against tubulin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

In vivo antitumor effect of an intracellular single-chain antibody fragment against the E7 oncoprotein of human papillomavirus 16.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Targeting endogenous nuclear antigens by electrotransfer of monoclonal antibodies in living cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Early or late-stage anti-N-terminal Huntingtin intrabody gene therapy reduces pathological features in B6.HDR6/1 mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Targeting the replisome with transduced monoclonal antibodies triggers lethal DNA replication stress in cancer cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Recent progress in generating intracellular functional antibody fragments to target and trace cellular components in living cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Engineering stable cytoplasmic intrabodies with designed specificity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Redox state of single chain Fv fragments targeted to the endoplasmic reticulum, cytosol and mitochondria.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990636

Anti-ovalbumin monoclonal antibodies interact with their antigen in internal membranes of Xenopus oocytes

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27570612

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Targeting tumor angiogenesis with adenovirus-delivered anti-Tie-2 intrabody

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27570612

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CSBJ.2016.07.003

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27570612%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27570612%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

2 references