(Q40498670)

21 September 2017

title

Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation (English)

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21 September 2017

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endoplasmic reticulum

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Vito Vetrugno

3

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Silvia Biocca

object named as

Silvia Biocca

6

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Maurizio Pocchiari

object named as

Maurizio Pocchiari

4

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author name string

Alessio Cardinale

1

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21 September 2017

Ilaria Filesi

2

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21 September 2017

Man-Sun Sy

5

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21 September 2017

language of work or name

English

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publication date

28 October 2004

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Journal of Biological Chemistry

21 September 2017

number of pages

10

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based on heuristic

inferred from page(s)

published in

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21 September 2017

volume

280

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21 September 2017

issue

1

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21 September 2017

page(s)

685-694

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https://api.crossref.org/works/10.1074%2FJBC.M407360200

21 September 2017

1 reference

Prions and the lymphoreticular system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Mammalian prion biology: one century of evolving concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Structural clues to prion replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Separation and properties of cellular and scrapie prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Prion protein conversions: insight into mechanisms, TSE transmission barriers and strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Trafficking, turnover and membrane topology of PrP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Stimulation of PrP(C) retrograde transport toward the endoplasmic reticulum increases accumulation of PrP(Sc) in prion-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Synthesis and trafficking of prion proteins in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Intracellular immunization with cytosolic recombinant antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Characterization of a new intrabody directed against the N-terminal region of human p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Diverting a protein from its cellular location by intracellular antibodies. The case of p21Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Reversion of transformed phenotype in ovarian cancer cells by intracellular expression of anti folate receptor antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Cloning immunoglobulin variable domains for expression by the polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Exploiting recombination in single bacteria to make large phage antibody libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Targeting vectors for intracellular immunisation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

The mode of action of Y13-259 scFv fragment intracellularly expressed in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Intracellular targeting and functional analysis of single-chain Fv fragments in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Prion protein expression in different species: analysis with a panel of new mAbs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Guanidine hydrochloride extraction and detection of prion proteins in mouse and hamster prion diseases by ELISA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Novel differences between two human prion strains revealed by two-dimensional gel electrophoresis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Redox state of single chain Fv fragments targeted to the endoplasmic reticulum, cytosol and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Further characterization of scrapie replication in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

The selection of intracellular antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Traffic jams II: an update of diseases of intracellular transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Aggresomes and Russell bodies. Symptoms of cellular indigestion?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Congenital disorders involving defective N-glycosylation of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Mutant prion protein-mediated aggregation of normal prion protein in the endoplasmic reticulum: implications for prion propagation and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407360200

21 January 2018

Identifiers

DOI

10.1074/JBC.M407360200

1 reference

21 September 2017

1 reference