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Paneth cell α-defensins and enteric microbiota in health and disease
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Europe PubMed Central
PMCID
4858879
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 April 2020
review article
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Europe PubMed Central
title
Paneth cell α-defensins and enteric microbiota in health and disease
(English)
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stated in
Europe PubMed Central
PMCID
4858879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
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2 April 2020
author
Tokiyoshi Ayabe
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4
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Europe PubMed Central
PMCID
4858879
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
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2 April 2020
author name string
Kiminori Nakamura
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1
1 reference
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Europe PubMed Central
PMCID
4858879
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
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2 April 2020
Naoya Sakuragi
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2
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Europe PubMed Central
PMCID
4858879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 April 2020
Akiko Takakuwa
series ordinal
3
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Europe PubMed Central
PMCID
4858879
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
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2 April 2020
language of work or name
English
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publication date
26 November 2015
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Europe PubMed Central
PMCID
4858879
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
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2 April 2020
published in
Bioscience of microbiota, food and health
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
4858879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 April 2020
volume
35
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stated in
Europe PubMed Central
PMCID
4858879
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
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2 April 2020
issue
2
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Europe PubMed Central
PMCID
4858879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 April 2020
page(s)
57-67
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Europe PubMed Central
PMCID
4858879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27200259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 April 2020
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mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
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Paneth cells regulate both chemotaxis of immature dendritic cells and cytokine production from epithelial cells.
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Alternative luminal activation mechanisms for paneth cell α-defensins
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28 September 2017
The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine
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28 September 2017
Paneth cell α-defensins in enteric innate immunity
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28 September 2017
Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
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28 September 2017
Paneth cells and innate mucosal immunity
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28 September 2017
Precursor processing of human defensin-5 is essential to the multiple functions in vitro and in vivo.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
ER stress and the unfolded protein response in intestinal inflammation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Enteric defensins are essential regulators of intestinal microbial ecology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Alpha-defensins in enteric innate immunity: functional Paneth cell alpha-defensins in mouse colonic lumen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Dynamic interactions between bacteria and immune cells leading to intestinal IgA synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Human defensins: synthesis and structural properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Paneth cells, defensins, and the commensal microbiota: a hypothesis on intimate interplay at the intestinal mucosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Mammalian defensins in the antimicrobial immune response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Mouse paneth cell secretory responses to cell surface glycolipids of virulent and attenuated pathogenic bacteria.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
The cathelicidins--structure, function and evolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Differential effects on human immunodeficiency virus type 1 replication by alpha-defensins with comparable bactericidal activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
The role of Paneth cells and their antimicrobial peptides in innate host defense.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Paneth cell trypsin is the processing enzyme for human defensin-5.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Activation of Paneth cell alpha-defensins in mouse small intestine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and by metaplastic Paneth cells in the colon in inflammatory bowel disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Carbamylcholine- and catecholamine-induced intracellular calcium dynamics of epithelial cells in mouse ileal crypts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Enteric defensins: antibiotic peptide components of intestinal host defense
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
Paneth cells of the human small intestine express an antimicrobial peptide gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 September 2017
A monoclonal antibody-based sandwich enzyme-linked immunosorbent assay for detection of secreted α-defensin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
31 May 2018
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
31 May 2018
The role of the gut microbiota in nonalcoholic fatty liver disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
31 May 2018
Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
31 May 2018
Mechanisms of alpha-defensin bactericidal action: comparative membrane disruption by Cryptdin-4 and its disulfide-null analogue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
31 May 2018
Sequence and specificity of two antibacterial proteins involved in insect immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
31 May 2018
Purification and primary structure of murine cryptdin-1, a Paneth cell defensin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
31 May 2018
Kinetics and possible regulation of crypt cell populations under normal and stress conditions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
31 May 2018
Reciprocal expression of enteric antimicrobial proteins in intestinal graft-versus-host disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Intestinal label-retaining cells are secretory precursors expressing Lgr5.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Reduced Paneth cell antimicrobial protein levels correlate with activation of the unfolded protein response in the gut of obese individuals.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Bactericidal activity of mouse α-defensin cryptdin-4 predominantly affects noncommensal bacteria.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Level of activation of the unfolded protein response correlates with Paneth cell apoptosis in human small intestine exposed to ischemia/reperfusion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Expression of the antimicrobial peptide alpha-defensin/cryptdins in intestinal crypts decreases at the initial phase of intestinal inflammation in a model of inflammatory bowel disease, IL-10-deficient mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Functional role of metaplastic paneth cell defensins in Helicobacter pylori-infected stomach.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Requirement of Notch activation during regeneration of the intestinal epithelia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Denatured human alpha-defensin attenuates the bactericidal activity and the stability against enzymatic digestion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Solution structure of cryptdin-4, a mouse paneth cell alpha-defensin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4858879
retrieved
28 November 2018
The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27200259
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Paneth cell development, differentiation, and function: new molecular cues
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27200259
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27200259
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.12938/BMFH.2015-019
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/o74czqbiqbacvjyfhokehdmngm
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
Fatcat ID
release_o74czqbiqbacvjyfhokehdmngm
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/o74czqbiqbacvjyfhokehdmngm
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
PMCID
4858879
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/o74czqbiqbacvjyfhokehdmngm
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
PubMed ID
27200259
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/o74czqbiqbacvjyfhokehdmngm
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
ResearchGate publication ID
284750267
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