(Q37719188)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

review article

1 reference

title

ER stress and the unfolded protein response in intestinal inflammation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Rajaraman Eri

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

I Das

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Rohan Lourie

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Timothy H Florin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

publication date

25 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Gastrointestinal and Liver Physiology

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

298

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

G820-32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis.

29 January 2020

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Dimerization of the human MUC2 mucin in the endoplasmic reticulum is followed by a N-glycosylation-dependent transfer of the mono- and dimers to the Golgi apparatus

21 January 2018

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Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

21 January 2018

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Modulation of host antimicrobial peptide (beta-defensins 1 and 2) expression during gastritis.

21 January 2018

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Coronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational Repression

21 January 2018

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Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

21 January 2018

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Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice

21 January 2018

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Altered colonic glycoprotein expression in unaffected monozygotic twins of inflammatory bowel disease patients.

21 January 2018

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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

21 January 2018

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Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response

21 January 2018

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Adaptation and increased susceptibility to infection associated with constitutive expression of misfolded SP-C.

21 January 2018

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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

21 January 2018

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

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UDP-Glc:glycoprotein glucosyltransferase recognizes structured and solvent accessible hydrophobic patches in molten globule-like folding intermediates

21 January 2018

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Getting in and out from calnexin/calreticulin cycles

21 January 2018

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Modulation of the unfolded protein response by the severe acute respiratory syndrome coronavirus spike protein

21 January 2018

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Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents.

21 January 2018

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Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein

21 January 2018

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OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

21 January 2018

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NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 January 2018

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MUC6 apomucin shows a distinct normal tissue distribution that correlates with Lewis antigen expression in the human stomach

21 January 2018

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HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats

21 January 2018

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Autophagy and pattern recognition receptors in innate immunity

21 January 2018

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Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2

21 January 2018

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Hepatitis C Virus Infection Induces Apoptosis through a Bax-Triggered, Mitochondrion-Mediated, Caspase 3-Dependent Pathway

21 January 2018

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Mucin gene (MUC 2 and MUC 5AC) upregulation by Gram-positive and Gram-negative bacteria.

21 January 2018

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Crohn's disease: transmission electron microscopic studies. II. Immunologic inflammatory response. Alterations of mast cells, basophils, eosinophils, and the microvasculature

21 January 2018

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Leptin modulates the expression of secreted and membrane-associated mucins in colonic epithelial cells by targeting PKC, PI3K, and MAPK pathways

21 January 2018

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Proinflammatory cytokines trigger MUC gene expression and mucin release in the intestinal cancer cell line LS180.

21 January 2018

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ATG16L1 T300A Shows Strong Associations With Disease Subgroups in a Large Australian IBD Population: Further Support for Significant Disease Heterogeneity

21 January 2018

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Butyrate specifically modulates MUC gene expression in intestinal epithelial goblet cells deprived of glucose.

21 January 2018

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The N terminus of the MUC2 mucin forms trimers that are held together within a trypsin-resistant core fragment.

21 January 2018

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Apoptotic pathways: ten minutes to dead

21 January 2018

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A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

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IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.

21 January 2018

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Defective post-transcriptional processing of MUC2 mucin in ulcerative colitis and in Crohn's disease increases detectability of the MUC2 protein core

21 January 2018

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Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

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Protein disulfide isomerase: a critical evaluation of its function in disulfide bond formation

21 January 2018

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Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

21 January 2018

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Regulation mechanisms and signaling pathways of autophagy

21 January 2018

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Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

21 January 2018

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Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome

21 January 2018

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Vasoactive intestinal peptide upregulates MUC2 intestinal mucin via CREB/ATF1.

21 January 2018

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Endoplasmic reticulum stress in disease: mechanisms and therapeutic opportunities

21 January 2018

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Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP

21 January 2018

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Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.

21 January 2018

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Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.

21 January 2018

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Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression

21 January 2018

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The effect of proteasome inhibitor MG132 on experimental inflammatory bowel disease.

21 January 2018

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Human cytomegalovirus infection activates and regulates the unfolded protein response

21 January 2018

1 reference

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The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response

21 January 2018

1 reference

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The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

21 January 2018

1 reference

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Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein

21 January 2018

1 reference

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Replication of a cytopathic strain of bovine viral diarrhea virus activates PERK and induces endoplasmic reticulum stress-mediated apoptosis of MDBK cells

21 January 2018

1 reference

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HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice

21 January 2018

1 reference

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Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2

21 January 2018

1 reference

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XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

21 January 2018

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Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

21 January 2018

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Interleukin-1beta induces MUC2 gene expression and mucin secretion via activation of PKC-MEK/ERK, and PI3K in human airway epithelial cells

21 January 2018

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Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

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ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

21 January 2018

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The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

21 January 2018

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Crohn's disease and the NOD2 gene: a role for paneth cells

21 January 2018

1 reference

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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

21 January 2018

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Shiga toxin 1 induces apoptosis through the endoplasmic reticulum stress response in human monocytic cells

21 January 2018

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Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells

21 January 2018

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Tumor necrosis factor-alpha induces mucin hypersecretion and MUC-2 gene expression by human airway epithelial cells

21 January 2018

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Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease

21 January 2018

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A membrane protein required for dislocation of misfolded proteins from the ER

21 January 2018

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IRE1 signaling affects cell fate during the unfolded protein response

21 January 2018

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Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma

21 January 2018

1 reference

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BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha

21 January 2018

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Interleukin-9 upregulates mucus expression in the airways

21 January 2018

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Bovine viral diarrhea virus 2 infection activates the unfolded protein response in MDBK cells, leading to apoptosis

21 January 2018

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Endoplasmic reticulum stress induces hyaluronan deposition and leukocyte adhesion

21 January 2018

1 reference

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Endoplasmic reticulum stress signaling in disease

21 January 2018

1 reference

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Regulated and unregulated pathways for MUC2 mucin secretion in human colonic LS180 adenocarcinoma cells are distinct

21 January 2018

1 reference

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West Nile Virus Infection Activates the Unfolded Protein Response, Leading to CHOP Induction and Apoptosis

21 January 2018

1 reference

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Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease

21 January 2018

1 reference

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Endoplasmic reticulum stress signaling transmitted by ATF6 mediates apoptosis during muscle development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Dissecting the ER-associated degradation of a misfolded polytopic membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/reperfusion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Mink epithelial cell killing by pathogenic murine leukemia viruses involves endoplasmic reticulum stress

21 January 2018

1 reference

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SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells.

21 January 2018

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Autophagy is activated for cell survival after endoplasmic reticulum stress

21 January 2018

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Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis

21 January 2018

1 reference

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Salmonella enteritidis FliC (flagella filament protein) induces human beta-defensin-2 mRNA production by Caco-2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

SPDEF regulates goblet cell hyperplasia in the airway epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum

21 January 2018

1 reference

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ER stress triggers apoptosis by activating BH3-only protein Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Activation of innate immune antiviral responses by Nod2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Regulation of ER stress-induced macroautophagy by protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Colonic expression of MUC2, MUC5AC, and TFF1 in inflammatory bowel disease in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Japanese encephalitis virus infection initiates endoplasmic reticulum stress and an unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Structure-activity relationships in beta-defensin peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

HLA-B27 misfolding in transgenic rats is associated with activation of the unfolded protein response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Sulphation and secretion of the predominant secretory human colonic mucin MUC2 in ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

One step at a time: endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Reduced Paneth cell alpha-defensins in ileal Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Defensin deficiency, intestinal microbes, and the clinical phenotypes of Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Defensins and other antimicrobial peptides in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Endoplasmic reticulum stress triggers autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00063.2010

21 January 2018

Identifiers

DOI

10.1152/AJPGI.00063.2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20338921%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference