(Q28591592)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

main subject

endoplasmic reticulum

0 references

Interferon gamma

1 reference

Eukaryotic translation initiation factor 2 alpha kinase 3

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Heather P Harding

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

David Ron

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Brian Popko

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

author name string

Heather P. Harding

2

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 May 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

published in

Journal of Cell Biology

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

volume

169

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

page(s)

603-612

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

issue

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

12 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity

17 March 2017

1 reference

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Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response

17 March 2017

1 reference

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The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

17 March 2017

1 reference

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Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

17 March 2017

1 reference

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

17 March 2017

1 reference

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

17 March 2017

1 reference

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Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter

17 March 2017

1 reference

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

17 March 2017

1 reference

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Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Regulated translation initiation controls stress-induced gene expression in mammalian cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Perk is essential for translational regulation and cell survival during the unfolded protein response

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

A trip to the ER: coping with stress

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Coupling endoplasmic reticulum stress to the cell death program

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

The oligodendrocyte and its many cellular processes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Translational control in the endoplasmic reticulum stress response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Why does remyelination fail in multiple sclerosis?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

The unfolding tale of the unfolded protein response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Blockade of gamma interferon might be beneficial in MS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Multiple sclerosis: current pathophysiological concepts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Foamy cells with oligodendroglial phenotype in childhood ataxia with diffuse central nervous system hypomyelination syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Cytokine induction of inducible nitric oxide synthase in an oligodendrocyte cell line: role of p38 mitogen-activated protein kinase activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

TNFalpha potentiates IFNgamma-induced cell death in oligodendrocyte progenitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Interferons in multiple sclerosis. A review of the evidence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Detailed in vivo analysis of interferon-gamma induced major histocompatibility complex expression in the the central nervous system: astrocytes fail to express major histocompatibility complex class I and II molecules.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Oligodendroglial response to the immune cytokine interferon gamma.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Developing and mature oligodendrocytes respond differently to the immune cytokine interferon-gamma.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

The effects of interferon-gamma on the central nervous system.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Immunohistochemical localization of phosphorylated protein kinase R and phosphorylated eukaryotic initiation factor-2 alpha in the central nervous system of SJL mice with experimental allergic encephalomyelitis.

3 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

Effects of interferon-gamma and tumor necrosis factor-alpha on survival and differentiation of oligodendrocyte progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

The effect of genotype on the natural history of eIF2B-related leukodystrophies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

Regional hypomyelination and dysplasia in transgenic mice with astrocyte-directed expression of interferon-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

21 January 2018

Caspase-12: an overview.

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

Interferon-gamma induced medulloblastoma in the developing cerebellum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

LPS/IFN-gamma cytotoxicity in oligodendroglial cells: role of nitric oxide and protection by the anti-inflammatory cytokine IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

The role of tumour necrosis factor, interleukin 6, interferon-gamma and inducible nitric oxide synthase in the development and pathology of the nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

Membrane biogenesis and the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

Nitric oxide-induced cell death in developing oligodendrocytes is associated with mitochondrial dysfunction and apoptosis-inducing factor translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200502086

GFAP promoter directs astrocyte-specific expression in transgenic mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171696

Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development

27 November 2018

1 reference

12 December 2020

Remyelination in multiple sclerosis

1 reference

12 December 2020

Endoplasmic reticulum stress in PLP-overexpressing transgenic rats: gray matter oligodendrocytes are more vulnerable than white matter oligodendrocytes

1 reference

12 December 2020

Major histocompatibility complex heavy chain accumulation in the endoplasmic reticulum of oligodendrocytes results in myelin abnormalities

1 reference

12 December 2020

Multiple sclerosis: a two-stage disease

1 reference

12 December 2020

Randomized study of antibodies to IFN-gamma and TNF-alpha in secondary progressive multiple sclerosis

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200502086

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911877%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

2 references