(Q26783009)

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Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease

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22 August 2022

Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease (English)

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12 references

23 March 2019

20 June 2019

3 August 2019

7 August 2019

25 September 2019

11 October 2019

12 October 2019

18 October 2019

22 October 2019

7 November 2019

19 November 2019

27 July 2020

bone marrow cells

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3 August 2019

lymphoid tissue

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7 August 2019

evasion of host immune response

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25 September 2019

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11 October 2019

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12 October 2019

hemic and immune systems

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18 October 2019

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22 October 2019

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7 November 2019

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7 November 2019

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19 November 2019

host microbial interaction

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27 July 2020

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Alexandre Morrot

4

1 reference

Europe PubMed Central

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1 June 2020

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Ana Flávia Nardy

1

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1 June 2020

Leonardo Santos

2

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1 June 2020

Célio Geraldo Freire-de-Lima

3

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1 June 2020

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4 August 2015

13 references

23 March 2019

20 June 2019

3 August 2019

7 August 2019

25 September 2019

11 October 2019

12 October 2019

18 October 2019

22 October 2019

7 November 2019

19 November 2019

27 July 2020

22 August 2022

BioMed Research International

15 references

23 March 2019

20 June 2019

3 August 2019

7 August 2019

25 September 2019

11 October 2019

12 October 2019

18 October 2019

22 October 2019

7 November 2019

19 November 2019

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26347020%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

27 July 2020

22 August 2022

2015

1 reference

Europe PubMed Central

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1 June 2020

709846

1 reference

Europe PubMed Central

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1 June 2020

copyright license

Creative Commons Attribution 3.0 Unported

13 references

Europe PubMed Central

23 March 2019

Europe PubMed Central

20 June 2019

Europe PubMed Central

3 August 2019

Europe PubMed Central

7 August 2019

Europe PubMed Central

25 September 2019

Europe PubMed Central

11 October 2019

Europe PubMed Central

12 October 2019

Europe PubMed Central

18 October 2019

Europe PubMed Central

22 October 2019

Europe PubMed Central

7 November 2019

Europe PubMed Central

19 November 2019

Europe PubMed Central

27 July 2020

Europe PubMed Central

22 August 2022

copyright status

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on focus list of Wikimedia project

0 references

S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress

1 reference

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The thymus is a common target organ in infectious diseases

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7 April 2017

Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses

2 references

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7 April 2017

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28 September 2017

Sphingosine 1-phosphate: a ligand for the EDG-1 family of G-protein-coupled receptors

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7 April 2017

Principles of bioactive lipid signalling: lessons from sphingolipids

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7 April 2017

Essential role for sphingosine kinases in neural and vascular development

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7 April 2017

Central tolerance: learning self-control in the thymus

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7 April 2017

Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

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7 April 2017

An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors

1 reference

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7 April 2017

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

1 reference

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7 April 2017

Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease

1 reference

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28 September 2017

Minireview: ubiquitination-regulated G protein-coupled receptor signaling and trafficking

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28 September 2017

A comprehensive review of the phenotype and function of antigen-specific immunoregulatory double negative T cells

1 reference

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28 September 2017

TNF-α is involved in the abnormal thymocyte migration during experimental Trypanosoma cruzi infection and favors the export of immature cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Chagasic thymic atrophy does not affect negative selection but results in the export of activated CD4+CD8+ T cells in severe forms of human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Signal integration and crosstalk during thymocyte migration and emigration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

The outs and the ins of sphingosine-1-phosphate in immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Critical roles for Rac GTPases in T-cell migration to and within lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Functional variants of the sphingosine-1-phosphate receptor 1 gene associate with asthma susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys

1 reference

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28 September 2017

The alliance of sphingosine-1-phosphate and its receptors in immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Selective attenuation of Toll-like receptor 2 signalling may explain the atheroprotective effect of sphingosine 1-phosphate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Vascular endothelium as a contributor of plasma sphingosine 1-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Finding a way out: lymphocyte egress from lymphoid organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Sphingosine-1 phosphate signaling regulates positioning of dendritic cells within the spleen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

The thymus is a common target in malnutrition and infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Src family kinases and lipid mediators in control of allergic inflammation

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28 September 2017

Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Involvement of sphingosine 1-phosphate (S1P) receptor type 1 and type 4 in migratory response of mouse T cells toward S1P.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Functions of the multifaceted family of sphingosine kinases and some close relatives

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Stress system activity, innate and T helper cytokines, and susceptibility to immune-related diseases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell-expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer patches.

1 reference

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28 September 2017

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28 September 2017

Sphingosine 1-phosphate inhibits migration of RBL-2H3 cells via S1P2: cross-talk between platelets and mast cells.

1 reference

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28 September 2017

Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis

1 reference

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28 September 2017

Transduction of Multiple Effects of Sphingosine 1-Phosphate (S1P) on T Cell Functions by the S1P1 G Protein-Coupled Receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Neuroendocrine control of thymus physiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival

1 reference

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28 September 2017

FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

T cell receptor gene diversity and selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 September 2017

Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

31 May 2018

Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics

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31 May 2018

Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

31 May 2018

Developmental stages in the human thymus.

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

Membrane type 1-matrix metalloproteinase (MT1-MMP) cooperates with sphingosine 1-phosphate to induce endothelial cell migration and morphogenic differentiation

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

S1P1 receptor expression regulates emergence of NKT cells in peripheral tissues.

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

Type 4 sphingosine 1-phosphate G protein-coupled receptor (S1P4) transduces S1P effects on T cell proliferation and cytokine secretion without signaling migration

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

Sphingosine-1-phosphate agonists increase macrophage homing, lymphocyte contacts, and endothelial junctional complex formation in murine lymph nodes

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

A hassle a day may keep the pathogens away: The fight-or-flight stress response and the augmentation of immune function

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

Experimental Trypanosoma cruzi infection alters the shaping of the central and peripheral T-cell repertoire.

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

T cell tolerance by clonal elimination in the thymus

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F709846

21 January 2018

Endogenous glucocorticoids cause thymus atrophy but are protective during acute Trypanosoma cruzi infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 November 2018

The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 November 2018

The human thymic microenvironment: new approaches to functional analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4539443

28 November 2018

Asynchronism of thymocyte development in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/26347020

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppressant FTY720 inhibits thymocyte emigration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26347020

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2015/709846

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26347020%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26347020%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26347020%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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