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Biomarkers of sepsis

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19 June 2019

4 August 2019

19 November 2020

Biomarkers of sepsis (English)

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clinical chemistry

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19 November 2020

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19 November 2020

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4 August 2019

author name string

James D. Faix

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language of work or name

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publication date

2013

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Critical Reviews in Clinical Laboratory Sciences

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19 June 2019

4 August 2019

19 November 2020

50

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1

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23-36

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Creative Commons Attribution-NonCommercial 3.0 Unported

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Europe PubMed Central

19 June 2019

Europe PubMed Central

4 August 2019

Europe PubMed Central

19 November 2020

on focus list of Wikimedia project

0 references

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Early goal-directed therapy in the treatment of severe sepsis and septic shock

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TREM-1 amplifies inflammation and is a crucial mediator of septic shock

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Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels

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Pathogen recognition by the innate immune system

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2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

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28 September 2017

Combining intermediate levels of the Endotoxin Activity Assay (EAA) with other biomarkers in the assessment of patients with sepsis: results of an observational study

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28 September 2017

Prognostic value and agreement of achieving lactate clearance or central venous oxygen saturation goals during early sepsis resuscitation

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28 September 2017

Early interleukin-6 and slope of monocyte human leukocyte antigen-DR: a powerful association to predict the development of sepsis after major trauma

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28 September 2017

Kidney failure related to broad-spectrum antibiotics in critically ill patients: secondary end point results from a 1200 patient randomised trial

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28 September 2017

The loss of homeostasis in hemostasis: new approaches in treating and understanding acute disseminated intravascular coagulation in critically ill patients

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28 September 2017

Soluble RAGE as a severity marker in community acquired pneumonia associated sepsis.

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28 September 2017

Increased interleukin-10 levels correlate with bacteremia and sepsis in febrile neutropenia pediatric oncology patients

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28 September 2017

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28 September 2017

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28 September 2017

Immunomodulatory therapy for sepsis: an update

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28 September 2017

The evolving experience with therapeutic TNF inhibition in sepsis: considering the potential influence of risk of death

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28 September 2017

Changes of monocyte human leukocyte antigen-DR expression as a reliable predictor of mortality in severe sepsis

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28 September 2017

Diagnostic accuracy of procalcitonin in critically ill immunocompromised patients

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28 September 2017

Procalcitonin algorithms for antibiotic therapy decisions: a systematic review of randomized controlled trials and recommendations for clinical algorithms

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28 September 2017

Biomarkers of endothelial dysfunction: can they help us deciphering systemic inflammation and sepsis?

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28 September 2017

Will polymerase chain reaction (PCR)-based diagnostics improve outcome in septic patients? A clinical view

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28 September 2017

The role of receptor for advanced glycation endproducts (RAGE) in infection

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28 September 2017

Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients.

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28 September 2017

Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients

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28 September 2017

Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma

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28 September 2017

Bench-to-bedside review: Circulating microparticles - a new player in sepsis?

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28 September 2017

The pathogenesis of sepsis.

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28 September 2017

The accuracy of the procalcitonin test for the diagnosis of neonatal sepsis: A meta-analysis

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28 September 2017

The harmful role of c5a on innate immunity in sepsis

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28 September 2017

Use of procalcitonin for the detection of sepsis in the critically ill burn patient: a systematic review of the literature

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28 September 2017

The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis

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28 September 2017

Bench-to-bedside review: the promise of rapid infection diagnosis during sepsis using polymerase chain reaction-based pathogen detection

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28 September 2017

Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis.

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28 September 2017

The role of T regulatory cells in human sepsis

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28 September 2017

Stratification is the key: inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis.

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28 September 2017

Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum.

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28 September 2017

Functions of the complement components C3 and C5 during sepsis

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28 September 2017

Antibacterial chemokines--actors in both innate and adaptive immunity

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28 September 2017

Procalcitonin assay in systemic inflammation, infection, and sepsis: clinical utility and limitations

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

Use of plasma C-reactive protein, procalcitonin, neutrophils, macrophage migration inhibitory factor, soluble urokinase-type plasminogen activator receptor, and soluble triggering receptor expressed on myeloid cells-1 in combination to diagnose infe

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28 September 2017

Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: systematic review and meta-analysis.

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28 September 2017

Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.

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28 September 2017

Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis.

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28 September 2017

The immunological consequences of injury

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28 September 2017

Impact of preanalytical variables on granulocytic surface antigen expression: a review

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28 September 2017

Interleukin-6, interleukin-8, and a rapid and sensitive assay for calcitonin precursors for the determination of bacterial sepsis in febrile neutropenic children

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28 September 2017

Interactions between the innate immune and blood coagulation systems

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28 September 2017

Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3613962

28 September 2017

Early lactate clearance is associated with improved outcome in severe sepsis and septic shock

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3613962

28 September 2017

Tumor necrosis factor as a pharmacological target.

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28 September 2017

High sensitivity C-reactive protein: an emerging role in cardiovascular risk assessment

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28 September 2017

Low serum procalcitonin level accurately predicts the absence of bacteremia in adult patients with acute fever

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3613962

28 September 2017

Procalcitonin, C-reactive protein and APACHE II score for risk evaluation in patients with severe pneumonia.

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28 September 2017

Cytokines and anticytokines in the pathogenesis of sepsis

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28 September 2017

Recognition of gram-negative bacteria and endotoxin by the innate immune system

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28 September 2017

Febrile infection changes the expression of IgG Fc receptors and complement receptors in human neutrophils in vivo

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28 September 2017

Interleukin 6 is a prognostic indicator of outcome in severe intra-abdominal sepsis

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28 September 2017

A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock

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28 September 2017

Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever

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28 September 2017

Blood lactate: biochemistry, laboratory methods, and clinical interpretation

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28 September 2017

The hematology of bacterial infections in premature infants

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28 September 2017

Persistent Sepsis-Induced Hypotension without Hyperlactatemia: A Distinct Clinical and Physiological Profile within the Spectrum of Septic Shock

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31 May 2018

Procalcitonin--a new indicator of the systemic response to severe infections

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31 May 2018

Clinical applications of C-reactive protein in pediatrics

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31 May 2018

Sepsis: a new hypothesis for pathogenesis of the disease process

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31 May 2018

National estimates of severe sepsis in United States emergency departments.

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21 January 2018

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference

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21 January 2018

Roger C. Bone, MD and the evolving paradigms of sepsis

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21 January 2018

Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1α, IL-1β or IL-1 receptor type I.

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21 January 2018

Diagnostic value of an interleukin-6 bedside test in term and preterm neonates at the time of clinical suspicion of early- and late-onset bacterial infection

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21 January 2018

Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality.

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21 January 2018

Immunoneutralization of the aminoprocalcitonin peptide of procalcitonin protects rats from lethal endotoxaemia: neuroendocrine and systemic studies

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21 January 2018

Procalcitonin as a Marker for the Detection of Bacteremia and Sepsis in the Emergency Department

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21 January 2018

Early serum procalcitonin, interleukin-6, and 24-hour lactate clearance: useful indicators of septic infections in severely traumatized patients

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21 January 2018

Procalcitonin-guided interventions against infections to increase early appropriate antibiotics and improve survival in the intensive care unit: a randomized trial.

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21 January 2018

The sensitivity of neutrophil CD64 expression as a biomarker of bacterial infection is low in critically ill patients.

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21 January 2018

Soluble TREM-1 is not suitable for distinguishing between systemic inflammatory response syndrome and sepsis survivors and nonsurvivors in the early stage of acute inflammation.

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21 January 2018

Measurement of plasma sTREM-1 in patients with severe sepsis receiving early goal-directed therapy and evaluation of its usefulness.

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21 January 2018

Soluble form of the receptor for advanced glycation end products is a marker of acute lung injury but not of severe sepsis in critically ill patients

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21 January 2018

A multicenter trial to compare blood culture with polymerase chain reaction in severe human sepsis.

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21 January 2018

A rapid assay of endotoxin in whole blood using autologous neutrophil dependent chemiluminescence

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21 January 2018

Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study

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21 January 2018

Enhanced T-cell apoptosis in human septic shock is associated with alteration of the costimulatory pathway.

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21 January 2018

Evaluation of neutrophilic CD64, interleukin 10 and procalcitonin as diagnostic markers of early- and late-onset neonatal sepsis

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21 January 2018

The effects of sepsis on mitochondria

1 reference

https://api.crossref.org/works/10.3109%2F10408363.2013.764490

21 January 2018

Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock

1 reference

https://api.crossref.org/works/10.3109%2F10408363.2013.764490

21 January 2018

Normal-range blood lactate concentration in septic shock is prognostic and predictive

1 reference

https://api.crossref.org/works/10.3109%2F10408363.2013.764490

21 January 2018

International Society on Thrombosis and Haemostasis score for overt disseminated intravascular coagulation predicts organ dysfunction and fatality in sepsis patients.

1 reference

https://api.crossref.org/works/10.3109%2F10408363.2013.764490

21 January 2018

Drotrecogin alfa (activated) in adults with septic shock.

1 reference

https://api.crossref.org/works/10.3109%2F10408363.2013.764490

21 January 2018

A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis

1 reference

https://api.crossref.org/works/10.3109%2F10408363.2013.764490

21 January 2018

The use of gene-expression profiling to identify candidate genes in human sepsis.

1 reference

https://api.crossref.org/works/10.3109%2F10408363.2013.764490

21 January 2018

A combined score of pro- and anti-inflammatory interleukins improves mortality prediction in severe sepsis

1 reference

https://api.crossref.org/works/10.3109%2F10408363.2013.764490

21 January 2018

Persisting elevation of C-reactive protein after pancreatic resections can indicate developing inflammatory complications

1 reference

https://api.crossref.org/works/10.3109%2F10408363.2013.764490

21 January 2018

Heparin-binding protein (HBP/CAP37): A missing link in neutrophil-evoked alteration of vascular permeability

1 reference

https://api.crossref.org/works/10.3109%2F10408363.2013.764490

21 January 2018

Pro- and anti-inflammatory responses are regulated simultaneously from the first moments of septic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3613962

28 November 2018

Efficacy of procalcitonin in the early diagnosis of bacterial infections in a critical care unit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3613962

28 November 2018

Evaluation of neutrophil CD64 expression and procalcitonin as useful markers in early diagnosis of sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3613962

28 November 2018

The systemic inflammatory response syndrome as a predictor of bacteraemia and outcome from sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Usefulness of presepsin in the diagnosis of sepsis in a multicenter prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sepsis-induced acute respiratory distress syndrome with fatal outcome is associated to increased serum transforming growth factor beta-1 levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-inflammatory response dominates after septic shock: association of low monocyte HLA-DR expression and high interleukin-10 concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictive value of procalcitonin and interleukin 6 in critically ill patients with suspected sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Usefulness of presepsin (sCD14-ST) measurements as a marker for the diagnosis and severity of sepsis that satisfied diagnostic criteria of systemic inflammatory response syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMGB1 as a predictor of organ dysfunction and outcome in patients with severe sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coincidence of pro- and anti-inflammatory responses in the early phase of severe sepsis: Longitudinal study of mononuclear histocompatibility leukocyte antigen-DR expression, procalcitonin, C-reactive protein, and changes in T-cell subsets in septic

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-analysis of procalcitonin for sepsis detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitous expression of the calcitonin-i gene in multiple tissues in response to sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and Role of Myeloid-related Protein-14 in Clinical and Experimental Sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil CD64 expression and serum IL-8: Sensitive early markers of severity and outcome in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential diagnostic value of procalcitonin in surgical and medical patients with septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety and efficacy of affinity-purified, anti–tumor necrosis factor-α, ovine fab for injection (CytoFab) in severe sepsis*

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination biomarkers to diagnose sepsis in the critically ill patient

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide binding protein in a surgical intensive care unit: A marker of sepsis?*

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock*

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement activation during sepsis in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

sRAGE is elevated in septic patients and associated with patients outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High serum procalcitonin concentrations in patients with sepsis and infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of adhesion molecules CD64, CD11b and CD62L in neutrophils and monocytes of peripheral blood for early diagnosis of neonatal infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23480440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3109/10408363.2013.764490

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

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