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Nucleic acid-based approaches to STAT inhibition
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PubMed
title
Nucleic acid-based approaches to STAT inhibition
(English)
1 reference
stated in
PubMed
author
Malabika Sen
series ordinal
1
object named as
Malabika Sen
1 reference
stated in
Crossref
Jennifer Rubin Grandis
series ordinal
2
object named as
Jennifer R. Grandis
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
1 October 2012
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stated in
PubMed
published in
JAK-STAT
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PubMed
volume
1
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PubMed
issue
4
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PubMed
page(s)
285-91
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PubMed
cites work
Structure, function, and regulation of STAT proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
7 April 2017
STAT3 as a therapeutic target in head and neck cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
7 April 2017
Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
7 April 2017
Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
7 April 2017
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
7 April 2017
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
7 April 2017
The STATs of cancer--new molecular targets come of age
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
7 April 2017
Stat3 as an oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
7 April 2017
First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Antitumor activity of NF-kB decoy oligodeoxynucleotides in a prostate cancer cell line.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Small interfering RNA targeted to IGF-IR delays tumor growth and induces proinflammatory cytokines in a mouse breast cancer model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Down-regulation of STAT3 expression by vector-based small interfering RNA inhibits pancreatic cancer growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Humanized Lewis-Y specific antibody based delivery of STAT3 siRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Targeted blockage of signal transducer and activator of transcription 5 signaling pathway with decoy oligodeoxynucleotides suppresses leukemic K562 cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Role of STAT3 decoy oligodeoxynucleotides on cell invasion and chemosensitivity in human epithelial ovarian cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Lentivirus-mediated shRNA interference targeting STAT3 inhibits human pancreatic cancer cell invasion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Inhibitory effects of decoy-ODN targeting activated STAT3 on human glioma growth in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Lack of toxicity of a STAT3 decoy oligonucleotide.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
T40214/PEI complex: a potent therapeutics for prostate cancer that targets STAT3 signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Inhibition of Stat3 activation and tumor growth suppression of non-small cell lung cancer by G-quartet oligonucleotides.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Advances in preclinical investigation of prostate cancer gene therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Delivery systems for the direct application of siRNAs to induce RNA interference (RNAi) in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
An oligonucleotide decoy for Stat3 activates the immune response of macrophages to breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Targeting signal transducer and activator of transcription 3 with G-quartet oligonucleotides: a potential novel therapy for head and neck cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Knockdown of Stat3 expression using RNAi inhibits growth of laryngeal tumors in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Inhibition of STAT3 expression by siRNA suppresses growth and induces apoptosis in laryngeal cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Novel single-stranded oligonucleotides that inhibit signal transducer and activator of transcription 3 induce apoptosis in vitro and in vivo in prostate cancer cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
G-quartet oligonucleotides: a new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Dominant-negative Stat5 inhibits growth and induces apoptosis in T47D-derived tumors in nude mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Transcription factor decoy oligonucleotides modified with locked nucleic acids: an in vitro study to reconcile biostability with binding affinity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Antisense oligonucleotide-based therapeutics for cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Targeting Stat3 with G-quartet oligodeoxynucleotides in human cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
E2F decoy oligodeoxynucleotides effectively inhibit growth of human tumor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
StAT signaling in cancer: insights into pathogenesis and treatment strategies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Signal transducer and activator of transcription proteins in leukemias.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
A genomic-scale view of the cAMP response element-enhancer decoy: a tumor target-based genetic tool
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Design and characterization of decoy oligonucleotides containing locked nucleic acids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
What does Stat3 do?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Differential function of STAT5 isoforms in head and neck cancer growth control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Epidermal growth factor receptor-dependent control of keratinocyte survival and Bcl-xL expression through a MEK-dependent pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Therapeutic applications of transcription factor decoy oligonucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Antisense Oligodeoxynucleotide Technology: Potential Use for the Treatment of Malignant Brain Tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Stat3 activation is required for cellular transformation by v-src
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
Naturally occurring dominant negative variants of Stat5.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 September 2017
The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
31 May 2018
Epidermal growth factor receptor--mediated stat3 signaling blocks apoptosis in head and neck cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.4161%2FJKST.22312
retrieved
21 January 2018
Naturally occurring dominant-negative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.4161%2FJKST.22312
retrieved
21 January 2018
Application of transcription factor "decoy" strategy as means of gene therapy and study of gene expression in cardiovascular disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.4161%2FJKST.22312
retrieved
21 January 2018
In vivo antitumor efficacy of STAT3 blockade using a transcription factor decoy approach: implications for cancer therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.4161%2FJKST.22312
retrieved
21 January 2018
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3670286
retrieved
28 November 2018
Functionally distinct isoforms of STAT5 are generated by protein processing
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24058785
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24058785
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transcription factor decoy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24058785
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: role for the cyclin-dependent kinase inhibitor p27(Kip1)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24058785
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Antiproliferative activity of G-quartet-containing oligonucleotides generated by a novel single-stranded DNA expression system
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24058785
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Targeting STAT3 in cancer: how successful are we?
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24058785
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4161/JKST.22312
0 references
Fatcat ID
release_6bqbqlvpxvc2rbgpsfcndrgsqy
0 references
PMCID
3670286
1 reference
stated in
PubMed
PubMed ID
24058785
1 reference
stated in
PubMed
ResearchGate publication ID
256931608
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