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Components of cancer metabolism and therapeutic interventions
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PubMed
title
Components of cancer metabolism and therapeutic interventions
(English)
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PubMed
author name string
John Singleterry
series ordinal
1
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Crossref
Annapoorna Sreedhar
series ordinal
2
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Crossref
Yunfeng Zhao
series ordinal
3
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language of work or name
English
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PubMed
publication date
July 2014
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PubMed
published in
Mitochondrion
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PubMed
volume
17
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PubMed
page(s)
50-5
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PubMed
cites work
Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
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PubMed Central
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7 April 2017
Hypoxia-inducible factors and the response to hypoxic stress
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PubMed Central
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7 April 2017
Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
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7 April 2017
Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
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PubMed Central
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7 April 2017
Regulation of cancer cell metabolism
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PubMed Central
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7 April 2017
Energy metabolism in tumor cells
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PubMed Central
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7 April 2017
Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children
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7 April 2017
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
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PubMed Central
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7 April 2017
Pyruvate kinase type M2 and its role in tumor growth and spreading
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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7 April 2017
Why do cancers have high aerobic glycolysis?
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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7 April 2017
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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7 April 2017
Otto Warburg's contributions to current concepts of cancer metabolism
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PubMed Central
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7 April 2017
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes
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7 April 2017
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
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7 April 2017
Principles of cancer therapy: oncogene and non-oncogene addiction
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PubMed Central
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7 April 2017
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
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PubMed Central
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7 April 2017
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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7 April 2017
Insulin and insulin-like growth factor signalling in neoplasia
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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7 April 2017
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
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PubMed Central
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7 April 2017
Metformin and reduced risk of cancer in diabetic patients
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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7 April 2017
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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7 April 2017
Retracted: Mitochondrial Dysfunction Promotes Breast Cancer Cell Migration and Invasion through HIF1α Accumulation via Increased Production of Reactive Oxygen Species
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
Dichloroacetate inhibits aerobic glycolysis in multiple myeloma cells and increases sensitivity to bortezomib.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
Intracellular delivery of redox cycler-doxorubicin to the mitochondria of cancer cell by folate receptor targeted mitocancerotropic liposomes
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PubMed Central
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28 September 2017
Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
p53: exercise capacity and metabolism
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells
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PubMed Central
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28 September 2017
Targeting the mitochondria activates two independent cell death pathways in ovarian cancer stem cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
Genetic insights into OXPHOS defect and its role in cancer
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PubMed Central
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28 September 2017
L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in Asian advanced hepatocellular carcinoma patients
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
Glucose deprivation-induced metabolic oxidative stress and cancer therapy
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
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PubMed Central
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28 September 2017
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
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PubMed Central
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28 September 2017
Somatic LKB1 mutations promote cervical cancer progression
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PubMed Central
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28 September 2017
Mitochondrial dysfunction and reactive oxygen species imbalance promote breast cancer cell motility through a CXCL14-mediated mechanism
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PubMed Central
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28 September 2017
Nampt: linking NAD biology, metabolism and cancer
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PubMed Central
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28 September 2017
Roles of p53, MYC and HIF-1 in regulating glycolysis - the seventh hallmark of cancer
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PubMed Central
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28 September 2017
Arginine deiminase, a potential anti-tumor drug
1 reference
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PubMed Central
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28 September 2017
An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone
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28 September 2017
Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.
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28 September 2017
A pivotal role for p53: balancing aerobic respiration and glycolysis
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28 September 2017
Regulation of tumor pH and the role of carbonic anhydrase 9.
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28 September 2017
Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability
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PubMed Central
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28 September 2017
Hypoxia signalling in cancer and approaches to enforce tumour regression
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28 September 2017
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis
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28 September 2017
THE EFFECT OF ARGINASE ON THE RETARDATION OF TUMOUR GROWTH.
1 reference
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PubMed Central
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28 September 2017
Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells.
1 reference
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PubMed Central
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28 September 2017
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
Use of ?-asparaginase in childhood ALL
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 September 2017
Engineering the substrate specificity of Escherichia coli asparaginase. II. Selective reduction of glutaminase activity by amino acid replacements at position 248.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
retrieved
31 May 2018
alpha-Ketoacids scavenge H2O2 in vitro and in vivo and reduce menadione-induced DNA injury and cytotoxicity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
retrieved
31 May 2018
Asparaginase-induced derangements of glutamine metabolism: the pathogenetic basis for some drug-related side-effects.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
retrieved
31 May 2018
MYC, microRNAs and glutamine addiction in cancers
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 November 2018
The interplay between MYC and HIF in cancer.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 November 2018
Increased HIF1α in SDH and FH deficient tumors does not cause microsatellite instability
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 November 2018
Adult Leydig Cell Tumors of the Testis Caused by Germline Fumarate Hydratase Mutations
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 November 2018
Analysis of fumarate hydratase mutations in a population-based series of early onset uterine leiomyosarcoma patients
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
retrieved
28 November 2018
Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 November 2018
Fasting serum glucose level and cancer risk in Korean men and women
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134411
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28 November 2018
Genetic analysis of mitochondrial complex II subunits SDHD, SDHB and SDHC in paraganglioma and phaeochromocytoma susceptibility
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PubMed Central
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28 November 2018
Mitochondrial impairment in p53-deficient human cancer cells
1 reference
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PubMed Central
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28 November 2018
High dose vitamin K3 infusion in advanced hepatocellular carcinoma
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24910195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inhibitory effect of tumor cell-derived lactic acid on human T cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24910195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Comparative pharmacokinetic studies of three asparaginase preparations
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24910195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.MITO.2014.05.010
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Fatcat ID
release_ljlwm6d4szghlf57mncum2di7u
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PMC publication ID
4134411
1 reference
stated in
PubMed
PubMed publication ID
24910195
1 reference
stated in
PubMed
ResearchGate publication ID
262941271
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