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Mitochondrial function and dysfunction: an update
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title
Mitochondrial function and dysfunction: an update
(English)
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author name string
R. E. Davis
series ordinal
1
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M. Williams
series ordinal
2
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language of work or name
English
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stated in
PubMed
publication date
September 2012
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PubMed
published in
Journal of Pharmacology and Experimental Therapeutics
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PubMed
volume
342
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PubMed
issue
3
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PubMed
page(s)
598-607
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PubMed
cites work
When a theory of aging ages badly.
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases
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reference URL
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Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implications
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Mitochondrial carriers function as monomers.
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Role of mitochondrial permeability transition pores in mitochondrial autophagy.
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Death by design: apoptosis, necrosis and autophagy
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
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The cell-non-autonomous nature of electron transport chain-mediated longevity
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7 January 2021
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The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Characterization of bioactive cell penetrating peptides from human cytochrome c: protein mimicry and the development of a novel apoptogenic agent
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Mitochondria: more than just a powerhouse
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Translational semantics and infrastructure: another search for the emperor's new clothes?
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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Treatment of mitochondrial disorders
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
The Alzheimer's disease mitochondrial cascade hypothesis: an update
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial dysfunction in cardiovascular disease
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Crossref
reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impact of PGC-1α on the topology and rate of superoxide production by the mitochondrial electron transport chain
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes.
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
A simplified model for mitochondrial ATP production.
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic models
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Crossref
reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
Energetics, epigenetics, mitochondrial genetics
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration?
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial fission/fusion dynamics and apoptosis
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Crossref
reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease: effects of β-amyloid on mitochondria
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: from respiration to apoptosis
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Estrogen related receptors (ERRs): a new dawn in transcriptional control of mitochondrial gene networks
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
VDAC, a multi-functional mitochondrial protein as a pharmacological target
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
Why are there no proven therapies for genetic mitochondrial diseases?
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
Pharmacological targeting of mitochondrial complex I deficiency: the cellular level and beyond.
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
Regulation and protection of mitochondrial physiology by sirtuins.
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
Mitochondrial calcium homeostasis as potential target for mitochondrial medicine
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
Functionalized nanosystems for targeted mitochondrial delivery
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Therapeutic prospects for mitochondrial disease
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria are sources of metabolic sink and arrhythmias
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Free radicals and antioxidants - quo vadis?
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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What is the mitochondrial permeability transition pore?
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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The in-depth evaluation of suspected mitochondrial disease
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Treatment of mitochondrial electron transport chain disorders: a review of clinical trials over the past decade
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial disease
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
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A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere dysfunction induces metabolic and mitochondrial compromise.
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting mitochondria for cancer therapy
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
The role of mitochondria in insulin resistance and type 2 diabetes mellitus
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of mitophagy
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Mitochondrial permeability transition in apoptosis and necrosis
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Monogenic mitochondrial disorders
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Apoptotic cell death "Nixed" by an ER-mitochondrial necrotic pathway
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Soluble adenylyl cyclase controls mitochondria-dependent apoptosis in coronary endothelial cells
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial morphology and cardiovascular disease
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1.
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Oxidative shielding or oxidative stress?
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial dysfunction in neurodegenerative diseases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mouse models resistant to diet-induced metabolic disease: is energy balance the key?
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7 January 2021
based on heuristic
inferred from DOI database lookup
Warburg revisited: regulation of mitochondrial metabolism by voltage-dependent anion channels in cancer cells
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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inferred from DOI database lookup
Bioenergetic effects of mitochondrial-targeted coenzyme Q analogs in endothelial cells
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria as a pharmacological target
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial diseases in man and mouse
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetics. Aging genes: the sirtuin story unravels
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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The magic garden
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7 January 2021
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Mitochondrial fusion and fission in mammals
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
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The role of mitochondria in apoptosis*.
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
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Inherited mitochondrial diseases of DNA replication
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Strategies for reducing or preventing the generation of oxidative stress
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting the mitochondrial permeability transition: cardiac ischemia-reperfusion versus carcinogenesis
1 reference
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Energy deficit in Huntington disease: why it matters
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial mutations: newly discovered players in neuronal degeneration.
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Organization and dynamics of human mitochondrial DNA.
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Antamanide, a derivative of Amanita phalloides, is a novel inhibitor of the mitochondrial permeability transition pore
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of Drp1, a key mitochondrial fission protein, in neuropathic pain
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
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A brief history of the status of transposable elements: from junk DNA to major players in evolution
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https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
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Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
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Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta
1 reference
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dimebon (latrepirdine) enhances mitochondrial function and protects neuronal cells from death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transcranial laser therapy attenuates amyloid-β peptide neuropathology in amyloid-β protein precursor transgenic mice
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Role of the mitochondrion in programmed necrosis
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
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Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
based on heuristic
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NSAIDs, Mitochondria and Calcium Signaling: Special Focus on Aspirin/Salicylates
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Mitochondrial DNA damage and animal longevity: insights from comparative studies
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reference URL
https://api.crossref.org/works/10.1124%2FJPET.112.192104
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7 January 2021
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Identifiers
DOI
10.1124/JPET.112.192104
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PubMed publication ID
22700430
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PubMed
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