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Epithelial Na(+) channel regulation by cytoplasmic and extracellular factors
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title
Epithelial Na(+) channel regulation by cytoplasmic and extracellular factors
(English)
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PubMed
author name string
Ossama B. Kashlan
series ordinal
1
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Crossref
Thomas R. Kleyman
series ordinal
2
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Crossref
language of work or name
English
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stated in
PubMed
publication date
15 May 2012
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stated in
PubMed
published in
Experimental Cell Research
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stated in
PubMed
volume
318
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stated in
PubMed
issue
9
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stated in
PubMed
page(s)
1011-9
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PubMed
cites work
Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Atomic force microscopy reveals the architecture of the epithelial sodium channel (ENaC)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Interaction of syntaxins with the amiloride-sensitive epithelial sodium channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Rab27a regulates epithelial sodium channel (ENaC) activity through synaptotagmin-like protein (SLP-5) and Munc13-4 effector mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Mechanosensation and the DEG/ENaC ion channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Membrane topology of the epithelial sodium channel in intact cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Functional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Nedd4-2 induces endocytosis and degradation of proteolytically cleaved epithelial Na+ channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Stimulation of the epithelial sodium channel (ENaC) by cAMP involves putative ERK phosphorylation sites in the C termini of the channel's beta- and gamma-subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
The Jpred 3 secondary structure prediction server
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
7 April 2017
Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
ENaC structure and function in the wake of a resolved structure of a family member
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Ubiquitin-specific protease 2-45 (Usp2-45) binds to epithelial Na+ channel (ENaC)-ubiquitylating enzyme Nedd4-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Regulation of the epithelial Na+ channel by the RH domain of G protein-coupled receptor kinase, GRK2, and Galphaq/11.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Base of the thumb domain modulates epithelial sodium channel gating
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Second transmembrane domain modulates epithelial sodium channel gating in response to shear stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Identification of epithelial Na+ channel (ENaC) intersubunit Cl- inhibitory residues suggests a trimeric alpha gamma beta channel architecture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Constraint-based, Homology Model of the Extracellular Domain of the Epithelial Na+ Channel α Subunit Reveals a Mechanism of Channel Activation by Proteases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Glucocorticoid-induced Leucine Zipper 1 Stimulates the Epithelial Sodium Channel by Regulating Serum- and Glucocorticoid-induced Kinase 1 Stability and Subcellular Localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
The cystic fibrosis transmembrane conductance regulator impedes proteolytic stimulation of the epithelial Na+ channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Hrs controls sorting of the epithelial Na+ channel between endosomal degradation and recycling pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
Cys Palmitoylation of the β Subunit Modulates Gating of the Epithelial Sodium Channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
The endoplasmic reticulum-associated degradation of the epithelial sodium channel requires a unique complement of molecular chaperones
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
New role for plasmin in sodium homeostasis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
Extracellular chloride regulates the epithelial sodium channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Activation of the epithelial Na+ channel in the collecting duct by vasopressin contributes to water reabsorption.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
ENaC at the cutting edge: regulation of epithelial sodium channels by proteases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Epithelial sodium channel regulated by differential composition of a signaling complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Extracellular protons regulate human ENaC by modulating Na+ self-inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor tone
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
An obligatory heterodimer of 14-3-3beta and 14-3-3epsilon is required for aldosterone regulation of the epithelial sodium channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Intracellular sodium regulates proteolytic activation of the epithelial sodium channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
The role of adrenal steroidogenesis in arterial hypertension
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
Adrenal steroids and the metabolic syndrome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
Regulation of the epithelial Na+ channel by the protein kinase CK2.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
Sodium channels and cystic fibrosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Differential activities of glucocorticoid-induced leucine zipper protein isoforms
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Phosphatidylinositol 4-phosphate 5-kinase reduces cell surface expression of the epithelial sodium channel (ENaC) in cultured collecting duct cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Molecular determinants of PI(4,5)P2 and PI(3,4,5)P3 regulation of the epithelial Na+ channel
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Small heat shock protein alphaA-crystallin regulates epithelial sodium channel expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Regulation of cation transport in the distal nephron by mechanical forces
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
AMP-activated kinase inhibits the epithelial Na+ channel through functional regulation of the ubiquitin ligase Nedd4-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Regulation of epithelial Na+ channels (ENaC) by methylation: a novel methyltransferase stimulates ENaC activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Rab4 GTP/GDP modulates amiloride-sensitive sodium channel (ENaC) function in colonic epithelia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Serum- and glucocorticoid-regulated kinase 1 regulates ubiquitin ligase neural precursor cell-expressed, developmentally down-regulated protein 4-2 by inducing interaction with 14-3-3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Acute ENaC stimulation by cAMP in a kidney cell line is mediated by exocytic insertion from a recycling channel pool
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
Distinct pools of epithelial sodium channels are expressed at the plasma membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
retrieved
28 September 2017
cAMP and serum and glucocorticoid-inducible kinase (SGK) regulate the epithelial Na(+) channel through convergent phosphorylation of Nedd4-2.
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28 September 2017
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels
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28 September 2017
Regulation of airway surface liquid volume by human airway epithelia
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28 September 2017
The role of individual Nedd4-2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels
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28 September 2017
Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na(+) transport
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28 September 2017
Patch-clamp studies on epithelial sodium channels in salivary duct cells
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28 September 2017
Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells
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28 September 2017
Phosphatidylinositol 4,5-bisphosphate (PIP2) stimulates epithelial sodium channel activity in A6 cells
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PubMed Central
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28 September 2017
Liddle syndrome: genetics and mechanisms of Na+ channel defects
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28 September 2017
Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel
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PubMed Central
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28 September 2017
Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation
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28 September 2017
Location and function of the epithelial Na channel in the cochlea.
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28 September 2017
Differential effects of protein kinase C on the levels of epithelial Na+ channel subunit proteins
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28 September 2017
Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination
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28 September 2017
Regulation of Na(+) reabsorption by the aldosterone-induced small G protein K-Ras2A.
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28 September 2017
SNAREs and SNARE regulators in membrane fusion and exocytosis
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28 September 2017
Epithelial sodium channel regulated by aldosterone-induced protein sgk.
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28 September 2017
Carboxylmethylation of the beta subunit of xENaC regulates channel activity
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PubMed Central
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28 September 2017
The amiloride-inhibitable Na+ conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
In vivo phosphorylation of the epithelial sodium channel
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28 September 2017
Loss of protein kinase C inhibition in the beta-T594M variant of the amiloride-sensitive Na+ channel
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28 September 2017
Expression of the cystic fibrosis phenotype in a renal amphibian epithelial cell line
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28 September 2017
Protein kinase regulation of a cloned epithelial Na+ channel
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28 September 2017
Cytosolic Na+ controls and epithelial Na+ channel via the Go guanine nucleotide-binding regulatory protein
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PubMed Central
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28 September 2017
Biochemical analysis of the membrane topology of the amiloride-sensitive Na+ channel
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 September 2017
An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane
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PubMed Central
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28 September 2017
Current-voltage curve of sodium channels and concentration dependence of sodium permeability in frog skin
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28 September 2017
Novel determinants of epithelial sodium channel gating within extracellular thumb domains
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31 May 2018
Proteolytic processing of the epithelial sodium channel gamma subunit has a dominant role in channel activation
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31 May 2018
Mutations in the pore region modify epithelial sodium channel gating by shear stress
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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31 May 2018
External nickel inhibits epithelial sodium channel by binding to histidine residues within the extracellular domains of alpha and gamma subunits and reducing channel open probability
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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31 May 2018
Regions in the carboxy terminus of alpha-bENaC involved in gating and functional effects of actin
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31 May 2018
Developmental and cellular expression pattern of epithelial sodium channel alpha, beta and gamma subunits in the inner ear of the rat.
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31 May 2018
Expression and regulation of normal and polymorphic epithelial sodium channel by human lymphocytes
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31 May 2018
CFTR as a cAMP-dependent regulator of sodium channels
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31 May 2018
Aldosterone-stimulated transmethylations are linked to sodium transport
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31 May 2018
Regulation of ENaC expression at the cell surface by Rab11.
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28 November 2018
Defining an inhibitory domain in the alpha-subunit of the epithelial sodium channel.
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28 November 2018
The deubiquitinating enzyme UCH-L3 regulates the apical membrane recycling of the epithelial sodium channel
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Purinergic control of apical plasma membrane PI(4,5)P2 levels sets ENaC activity in principal cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Intracellular trafficking of a polymorphism in the COOH terminus of the alpha-subunit of the human epithelial sodium channel is modulated by casein kinase 1.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Functional role of extracellular loop cysteine residues of the epithelial Na+ channel in Na+ self-inhibition
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Lack of a role of membrane-protein interactions in flow-dependent activation of ENaC.
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28 November 2018
Mechano-sensitivity of epithelial sodium channels (ENaCs): laminar shear stress increases ion channel open probability
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Early aldosterone-induced gene product regulates the epithelial sodium channel by deubiquitylation
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: a mechanism for sodium hyperabsorption in cystic fibrosis.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Open probability of the epithelial sodium channel is regulated by intracellular sodium
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28 November 2018
Mechanism underlying flow stimulation of sodium absorption in the mammalian collecting duct
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28 November 2018
Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Functional polymorphisms in the alpha-subunit of the human epithelial Na+ channel increase activity.
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28 November 2018
Differential modulation of a polymorphism in the COOH terminus of the alpha-subunit of the human epithelial sodium channel by protein kinase Cdelta
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Identification of a functional phosphatidylinositol 3,4,5-trisphosphate binding site in the epithelial Na+ channel.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Purinergic inhibition of the epithelial Na+ transport via hydrolysis of PIP2.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Receptor tyrosine kinases mediate epithelial Na(+) channel inhibition by epidermal growth factor
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Degenerin/epithelial Na+ channel proteins: components of a vascular mechanosensor
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Extracellular Zn2+ activates epithelial Na+ channels by eliminating Na+ self-inhibition
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Functional polymorphism in the carboxyl terminus of the alpha-subunit of the human epithelial sodium channel
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Syntaxin 1A regulates ENaC channel activity.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Maturation of the epithelial Na+ channel involves proteolytic processing of the alpha- and gamma-subunits
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Syntaxin 1A regulates ENaC via domain-specific interactions.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Casein kinase 2 specifically binds to and phosphorylates the carboxy termini of ENaC subunits
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Amiloride, a specific drug for hypertension in black people with T594M variant?
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Na transport proteins are expressed by rat alveolar epithelial type I cells
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28 November 2018
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC).
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28 November 2018
A single WW domain is the predominant mediator of the interaction between the human ubiquitin-protein ligase Nedd4 and the human epithelial sodium channel
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Toward Understanding the Role of Methylation in Aldosterone-Sensitive Na(+) Transport
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28 November 2018
Epithelial Na(+) channels are regulated by flow
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Antisense oligonucleotides against the alpha-subunit of ENaC decrease lung epithelial cation-channel activity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698959
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28 November 2018
Mutational analysis of cysteine-rich domains of the epithelium sodium channel (ENaC). Identification of cysteines essential for channel expression at the cell surface
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28 November 2018
Differential expression of RNA and protein of the three pore-forming subunits of the amiloride-sensitive epithelial sodium channel in taste buds of the rat
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28 November 2018
Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome
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28 November 2018
Association of hypertension with T594M mutation in beta subunit of epithelial sodium channels in black people resident in London
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28 November 2018
The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis
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28 November 2018
Localization of epithelial sodium channel subunit mRNAs in adult rat lung by in situ hybridization
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28 November 2018
Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice
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28 November 2018
Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans
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28 November 2018
Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways
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Quantitation and localization of ENaC subunit expression in fetal, newborn, and adult mouse lung
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7 January 2021
Immunochemical analysis of the sodium channel in rodent and human eye
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reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.024
retrieved
7 January 2021
Deactivation of vasodilator responses by GRK2 overexpression: a mechanism or the mechanism for hypertension?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.024
retrieved
7 January 2021
Rho small GTPases activate the epithelial Na(+) channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.024
retrieved
7 January 2021
Methylation increases sodium transport into A6 apical membrane vesicles: possible mode of aldosterone action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.024
retrieved
7 January 2021
Epithelial sodium channel in human epidermal keratinocytes: expression of its subunits and relation to sodium transport and differentiation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22405998
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.YEXCR.2012.02.024
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4543525
OpenCitations bibliographic resource ID
4543525
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4543525
PMC publication ID
3698959
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4543525
PubMed publication ID
22405998
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4543525
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