(Q51813999)

13 April 2018

title

Identification of a functional phosphatidylinositol 3,4,5-trisphosphate binding site in the epithelial Na+ channel. (English)

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13 April 2018

author

Alexander Staruschenko

2

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13 April 2018

author name string

Oleh Pochynyuk

1

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13 April 2018

Qiusheng Tong

3

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13 April 2018

Jorge Medina

4

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13 April 2018

James D Stockand

5

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13 April 2018

language of work or name

English

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publication date

9 September 2005

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13 April 2018

Journal of Biological Chemistry

published in

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13 April 2018

volume

280

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13 April 2018

page(s)

37565-37571

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13 April 2018

issue

45

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13 April 2018

Alterations in conserved Kir channel-PIP2 interactions underlie channelopathies

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1 reference

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pH gating of ROMK (K(ir)1.1) channels: control by an Arg-Lys-Arg triad disrupted in antenatal Bartter syndrome

21 January 2018

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Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome

21 January 2018

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PIP2 binding residues of Kir2.1 are common targets of mutations causing Andersen syndrome.

21 January 2018

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Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactions.

21 January 2018

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PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels.

21 January 2018

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Localization of the ATP/phosphatidylinositol 4,5 diphosphate-binding site to a 39-amino acid region of the carboxyl terminus of the ATP-regulated K+ channel Kir1.1.

21 January 2018

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A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity

21 January 2018

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Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis

21 January 2018

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3-phosphoinositides modulate cyclic nucleotide signaling in olfactory receptor neurons

21 January 2018

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Modulation of the olfactory CNG channel by Ptdlns(3,4,5)P3.

21 January 2018

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Localization of PIP2 activation gate in inward rectifier K+ channels

21 January 2018

1 reference

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Epithelial sodium channel related to proteins involved in neurodegeneration

21 January 2018

1 reference

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Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

21 January 2018

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Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.

21 January 2018

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Molecular mechanisms of human hypertension

21 January 2018

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Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

21 January 2018

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The serum- and glucocorticoid-induced kinase is a physiological mediator of aldosterone action

21 January 2018

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sgk: an essential convergence point for peptide and steroid hormone regulation of ENaC-mediated Na+ transport

21 January 2018

1 reference

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Insulin-stimulated trafficking of ENaC in renal cells requires PI 3-kinase activity

21 January 2018

1 reference

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Regulation of Na(+) reabsorption by the aldosterone-induced small G protein K-Ras2A.

21 January 2018

1 reference

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Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling

21 January 2018

1 reference

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Direct activation of the epithelial Na(+) channel by phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate produced by phosphoinositide 3-OH kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Specificity of activation by phosphoinositides determines lipid regulation of Kir channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of kir channels by diverse modulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Multiple PIP2 binding sites in Kir2.1 inwardly rectifying potassium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

The role of NH2-terminal positive charges in the activity of inward rectifier KATP channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Structural and functional determinants of conserved lipid interaction domains of inward rectifying Kir6.2 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Structural determinants of PIP(2) regulation of inward rectifier K(ATP) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Epithelial Na+ channel subunit stoichiometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

A region directly following the second transmembrane domain in gamma ENaC is required for normal channel gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Identification of Cytoplasmic Domains within the Epithelial Na+Channel Reactive at the Plasma Membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function.

21 January 2018

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T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Real-time three-dimensional imaging of lipid signal transduction: apical membrane insertion of epithelial Na(+) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Phosphatidylinositol 4,5-bisphosphate (PIP2) stimulates epithelial sodium channel activity in A6 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

Purinergic inhibition of the epithelial Na+ transport via hydrolysis of PIP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509071200

21 January 2018

Identifiers

DOI

10.1074/JBC.M509071200

1 reference

13 April 2018

PubMed ID

16154997

1 reference

13 April 2018