(Q40508864)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1 (English)

1 reference

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3 January 2020

2

1 reference

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3 January 2020

Daniel Auguin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

Makoto Hiromura

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Toshiyuki Obata

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Takeshi Shibata

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Christian Roumestand

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Masayuki Noguchi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

language of work or name

English

0 references

publication date

30 September 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

3 January 2020

published in

1 reference

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3 January 2020

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

page(s)

53407-53418

1 reference

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3 January 2020

issue

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

3 January 2020

cites work

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The phosphoinositide 3-kinase pathway

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Ten years of protein kinase B signalling: a hard Akt to follow

21 January 2018

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Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

21 January 2018

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Solution structure and backbone dynamics of the pleckstrin homology domain of the human protein kinase B (PKB/Akt). Interaction with inositol phosphates

21 January 2018

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Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation

21 January 2018

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Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

21 January 2018

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Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change

21 January 2018

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High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate

21 January 2018

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The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

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Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

21 January 2018

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Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains

21 January 2018

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Essential role of PDK1 in regulating cell size and development in mice

21 January 2018

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In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation

21 January 2018

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Unravelling the activation mechanisms of protein kinase B/Akt

21 January 2018

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Cellular survival: a play in three Akts

21 January 2018

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Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

21 January 2018

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Targeting the PI3K-Akt pathway in human cancer: rationale and promise

21 January 2018

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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

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The protooncogene TCL1 is an Akt kinase coactivator

21 January 2018

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Tcl1 enhances Akt kinase activity and mediates its nuclear translocation

21 January 2018

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Akt is TCL-ish: implications for B-cell lymphoma.

21 January 2018

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Structural basis for the co-activation of protein kinase B by T-cell leukemia-1 (TCL1) family proto-oncoproteins.

21 January 2018

1 reference

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Identification of Akt association and oligomerization domains of the Akt kinase coactivator TCL1

21 January 2018

1 reference

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Differential regulation of Akt kinase isoforms by the members of the TCL1 oncogene family

21 January 2018

1 reference

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The role of TCL1 in human T-cell leukemia

21 January 2018

1 reference

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TCL1 participates in early embryonic development and is overexpressed in human seminomas

21 January 2018

1 reference

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TCL1: a new drug target in lymphoid and germ-cell malignancies?

21 January 2018

1 reference

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The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK.

21 January 2018

1 reference

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PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

21 January 2018

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Toward a PKB inhibitor: modification of a selective PKA inhibitor by rational design

21 January 2018

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Sequence-based design of kinase inhibitors applicable for therapeutics and target identification

21 January 2018

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Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.

21 January 2018

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Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

21 January 2018

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Malignant progression of a mouse fibrosarcoma by host cells reactive to a foreign body (gelatin sponge)

21 January 2018

1 reference

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Crystal structure of p14TCL1, an oncogene product involved in T-cell prolymphocytic leukemia, reveals a novel beta-barrel topology

21 January 2018

1 reference

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A modeled hydrophobic domain on the TCL1 oncoprotein mediates association with AKT at the cytoplasmic membrane

21 January 2018

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In vivo protein transduction: delivery of a biologically active protein into the mouse

21 January 2018

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Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

21 January 2018

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Involvement of the pleckstrin homology domain in the insulin-stimulated activation of protein kinase B.

21 January 2018

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Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

21 January 2018

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Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

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Role of translocation in the activation and function of protein kinase B

21 January 2018

1 reference

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Pleckstrin homology domains and the cytoskeleton

21 January 2018

1 reference

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Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

21 January 2018

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Cellular signaling: pivoting around PDK-1.

21 January 2018

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Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains

21 January 2018

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Signal-dependent membrane targeting by pleckstrin homology (PH) domains

21 January 2018

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Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression

21 January 2018

1 reference

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Reversal of the Ras-induced transformed phenotype by HR12, a novel ras farnesylation inhibitor, is mediated by the Mek/Erk pathway

21 January 2018

1 reference

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Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403775200

PKB binding proteins. Getting in on the Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403775200

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403775200

Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403775200

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403775200

21 January 2018

Identifiers

DOI

10.1074/JBC.M403775200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15459205%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference