(Q26825393)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

review article

1 reference

title

Pancreatic α-Cell Dysfunction in Type 2 Diabetes: Old Kids on the Block (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Jun Sung Moon

series ordinal

1

2 references

Crossref

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

1 reference

1 February 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

Diabetes & metabolism journal

1 March 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

39

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

issue

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

1-9

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

1 March 2020

copyright license

start time

1 January 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

1 reference

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The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia

7 April 2017

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Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes

7 April 2017

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Roux-en-Y gastric bypass and sleeve gastrectomy: mechanisms of diabetes remission and role of gut hormones

7 April 2017

1 reference

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Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

7 April 2017

1 reference

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Glucagon and type 2 diabetes: the return of the alpha cell.

7 April 2017

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Two novel glucagon receptor antagonists prove effective therapeutic agents in high-fat-fed and obese diabetic mice

28 September 2017

1 reference

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The effect of glargine versus glimepiride on pancreatic β-cell function in patients with type 2 diabetes uncontrolled on metformin monotherapy: open-label, randomized, controlled study.

28 September 2017

1 reference

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Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes

28 September 2017

1 reference

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Characterisation of structurally modified analogues of glucagon as potential glucagon receptor antagonists

28 September 2017

1 reference

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desHis¹Glu⁹-glucagon-[mPEG] and desHis¹Glu⁹(Lys³⁰PAL)-glucagon: long-acting peptide-based PEGylated and acylated glucagon receptor antagonists with potential antidiabetic activity.

28 September 2017

1 reference

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Regulation of glucagon secretion in normal and diabetic human islets by γ-hydroxybutyrate and glycine

28 September 2017

1 reference

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Incretin-based therapies for type 2 diabetes mellitus: a review of direct comparisons of efficacy, safety and patient satisfaction

28 September 2017

1 reference

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GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus

28 September 2017

1 reference

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Minireview: Glucagon in the pathogenesis of hypoglycemia and hyperglycemia in diabetes

28 September 2017

1 reference

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Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes

28 September 2017

1 reference

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Glucagon antagonism as a potential therapeutic target in type 2 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Pancreatic alpha cell mass in European subjects with type 2 diabetes

28 September 2017

1 reference

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Paracrinology of islets and the paracrinopathy of diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Pathogenesis of fasting and postprandial hyperglycemia in type 2 diabetes: implications for therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Weight loss and incretin responsiveness improve glucose control independently after gastric bypass surgery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Islet cell antibody-positive versus -negative phenotypic type 2 diabetes in youth: does the oral glucose tolerance test distinguish between the two?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Insulin signaling in alpha cells modulates glucagon secretion in vivo

28 September 2017

1 reference

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Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus

28 September 2017

1 reference

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K(ATP)-channels and glucose-regulated glucagon secretion

28 September 2017

1 reference

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Insulin as a physiological modulator of glucagon secretion

28 September 2017

1 reference

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The role of alpha-cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications

28 September 2017

1 reference

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Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains

28 September 2017

1 reference

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The biology of incretin hormones

28 September 2017

1 reference

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Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system

28 September 2017

1 reference

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Beta-cell function, insulin sensitivity, and glucose tolerance in obese diabetic and nondiabetic adolescents and young adults

28 September 2017

1 reference

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Alpha cell function in health and disease: influence of glucagon-like peptide-1.

28 September 2017

1 reference

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New insights into the regulation of glucagon secretion by glucagon-like peptide-1.

28 September 2017

1 reference

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Glucagon and regulation of glucose metabolism

28 September 2017

1 reference

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Autonomic regulation of islet hormone secretion--implications for health and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Exendin(9-39)amide is an antagonist of glucagon-like peptide-1(7-36)amide in humans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Elimination of the action of glucagon-like peptide 1 causes an impairment of glucose tolerance after nutrient ingestion by healthy baboons

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Acute and chronic effects of sulfonylurea drugs on pancreatic islet function in man

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Studies of pancreatic alpha cell function in normal and diabetic subjects

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Glucagon-stimulating activity of 20 amino acids in dogs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Glucagon physiology and pathophysiology in the light of new advances

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Hyperglucagonemia and insulin-mediated glucose metabolism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Evidence for an important role of glucagon in the regulation of hepatic glucose production in normal man.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Role of glucagon in the pathogenesis of diabetes: The status of the controversy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Hypertrophy and hyperplasia of somatostatin-containing D-cells in diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

The essential role of glucagon in the pathogenesis of diabetes mellitus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Somatostatin — both hormone and neurotransmitter?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Long-term effects of bariatric surgery on meal disposal and β-cell function in diabetic and nondiabetic patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Impact of lack of suppression of glucagon on glucose tolerance in humans

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Role of glucagon in maintenance of euglycemia in fed and fasted rats.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Glucagon dynamics during hypoglycaemia and food-re-challenge following treatment with vildagliptin in insulin-treated patients with type 2 diabetes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Going with the flow: adaptation of β-cell function to glucose fluxes after bariatric surgery

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Glucagon dose-response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Hypoglycemia-associated autonomic failure in advanced type 2 diabetes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Impaired glucose tolerance (IGT) is associated with reduced insulin-induced suppression of glucagon concentrations

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Islet dysfunction in insulin resistance involves impaired insulin secretion and increased glucagon secretion in postmenopausal women with impaired glucose tolerance.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342530

Hyperglucagonemia and Blood Glucose Regulation in Normal, Obese and Diabetic Subjects

28 November 2018

1 reference

12 December 2020

Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus

1 reference

12 December 2020

Correlation between minimal secretory capacity of pancreatic beta-cells and stability of diabetic control

1 reference

12 December 2020

Dose-response for glucagonostatic effect of amylin in rats

1 reference

12 December 2020

Assessment of hepatic sensitivity to glucagon in NIDDM: use as a tool to estimate the contribution of the indirect pathway to nocturnal glycogen synthesis

1 reference

12 December 2020

Cellular composition of the human diabetic pancreas

1 reference

12 December 2020

Effect of Insulin on the Exaggerated Glucagon Response to Arginine Stimulation in Diabetes Mellitus

1 reference

12 December 2020

Failure of glucagon suppression contributes to postprandial hyperglycaemia in IDDM

1 reference

12 December 2020

Glucagon and insulin: a bihormonal system

1 reference

12 December 2020

Hyperglucagonemia and its suppression. Importance in the metabolic control of diabetes

1 reference

12 December 2020

Hyperglucagonemia in diabetic ketoacidosis. Its prevalence and significance

1 reference

12 December 2020

Hyperglycemia of Diabetic Rats Decreased by a Glucagon Receptor Antagonist

1 reference

12 December 2020

Documentation of hyperglucagonemia throughout the day in nonobese and obese patients with noninsulin-dependent diabetes mellitus

1 reference

12 December 2020

Identifiers

DOI

10.4093/DMJ.2015.39.1.1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

25729706

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25729706%20AND%20SRC:MED&resulttype=core&format=json