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Molecular and genetic basis of sudden cardiac death
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review article
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Europe PubMed Central
title
Molecular and genetic basis of sudden cardiac death
(English)
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author name string
Alfred L. George
series ordinal
1
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language of work or name
English
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publication date
January 2013
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PubMed
published in
Journal of Clinical Investigation
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PubMed
volume
123
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PubMed
issue
1
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PubMed
page(s)
75-83
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PubMed
cites work
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Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human
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Calsequestrin 2 and arrhythmias
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KCNE5 (KCNE1L) variants are novel modulators of Brugada syndrome and idiopathic ventricular fibrillation
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Cardiac Na+ current regulation by pyridine nucleotides
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Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test
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GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A
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7 April 2017
Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex
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Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans
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Mutation of an A-kinase-anchoring protein causes long-QT syndrome
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Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias
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PubMed Central
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SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome
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Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death
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Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome
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Molecular basis of ranolazine block of LQT-3 mutant sodium channels: evidence for site of action
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Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations
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7 April 2017
A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene
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7 April 2017
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death
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7 April 2017
Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)
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7 April 2017
Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome
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7 April 2017
MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia
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7 April 2017
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
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7 April 2017
A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome
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7 April 2017
Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias
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7 April 2017
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome
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7 April 2017
A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
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7 April 2017
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
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7 April 2017
Identification of a Kir3.4 mutation in congenital long QT syndrome
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7 April 2017
Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
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7 April 2017
Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)
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7 April 2017
Transient outward current (I(to)) gain-of-function mutations in the KCND3-encoded Kv4.3 potassium channel and Brugada syndrome
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7 April 2017
Gain-of-function mutation S422L in the KCNJ8-encoded cardiac K(ATP) channel Kir6.1 as a pathogenic substrate for J-wave syndromes
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7 April 2017
A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel
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7 April 2017
Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia
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7 April 2017
A common polymorphism associated with antibiotic-induced cardiac arrhythmia
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Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2
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7 April 2017
Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts
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7 April 2017
Genetic basis and molecular mechanism for idiopathic ventricular fibrillation
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7 April 2017
KCNE1 mutations cause jervell and Lange-Nielsen syndrome
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PubMed Central
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7 April 2017
Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias
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7 April 2017
Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia
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Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a
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Genetic mutations and mechanisms in dilated cardiomyopathy
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28 September 2017
Novel rare variants in congenital cardiac arrhythmia genes are frequent in drug-induced torsades de pointes.
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28 September 2017
Torsades de pointes following acute myocardial infarction: evidence for a deadly link with a common genetic variant
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28 September 2017
Epidemiology and genetics of sudden cardiac death
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28 September 2017
A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes
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28 September 2017
Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop
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28 September 2017
Drug-induced long QT syndrome
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28 September 2017
Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model
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28 September 2017
A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype
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28 September 2017
Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current
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28 September 2017
Common genetic variants in sudden cardiac death
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PubMed Central
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28 September 2017
Prevalence of the congenital long-QT syndrome.
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28 September 2017
Beta-adrenergic signaling accelerates and synchronizes cardiac ryanodine receptor response to a single L-type Ca2+ channel
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PubMed Central
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28 September 2017
Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome
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28 September 2017
Determinants of prolonged QT interval and their contribution to sudden death risk in coronary artery disease: the Oregon Sudden Unexpected Death Study
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28 September 2017
Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia
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PubMed Central
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28 September 2017
Proarrhythmic defects in Timothy syndrome require calmodulin kinase II.
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28 September 2017
Ranolazine shortens repolarization in patients with sustained inward sodium current due to type-3 long-QT syndrome
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28 September 2017
Cardiac fibrillation: from ion channels to rotors in the human heart
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28 September 2017
Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome
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28 September 2017
The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels
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28 September 2017
Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutation
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28 September 2017
Zebrafish model for human long QT syndrome
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28 September 2017
Sodium channel kinetic changes that produce Brugada syndrome or progressive cardiac conduction system disease.
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28 September 2017
SCN5A polymorphism restores trafficking of a Brugada syndrome mutation on a separate gene.
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28 September 2017
A novel SCN5A mutation, F1344S, identified in a patient with Brugada syndrome and fever-induced ventricular fibrillation
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28 September 2017
Cellular basis for electrocardiographic and arrhythmic manifestations of Andersen-Tawil syndrome (LQT7).
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28 September 2017
Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism
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PubMed Central
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28 September 2017
Long QT syndrome: reduced repolarization reserve and the genetic link
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28 September 2017
Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study.
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28 September 2017
Pathophysiological mechanisms of Brugada syndrome: depolarization disorder, repolarization disorder, or more?
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28 September 2017
Electrocardiographic features in Andersen-Tawil syndrome patients with KCNJ2 mutations: characteristic T-U-wave patterns predict the KCNJ2 genotype
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28 September 2017
A trafficking defective, Brugada syndrome-causing SCN5A mutation rescued by drugs
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28 September 2017
Sudden death associated with short-QT syndrome linked to mutations in HERG.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Defective Potassium Channel Kir2.1 Trafficking Underlies Andersen-Tawil Syndrome
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Short QT Syndrome: a familial cause of sudden death
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Molecular dissection of the inward rectifier potassium current (IK1) in rabbit cardiomyocytes: evidence for heteromeric co-assembly of Kir2.1 and Kir2.2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Functional role of inward rectifier current in heart probed by Kir2.1 overexpression and dominant-negative suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Function, subcellular localization and assembly of a novel mutation of KCNJ2 in Andersen's syndrome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
KCNJ2 mutation results in Andersen syndrome with sex-specific cardiac and skeletal muscle phenotypes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Expression and intracellular localization of an SCN5A double mutant R1232W/T1620M implicated in Brugada syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Sudden cardiac death in the United States, 1989 to 1998.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Enhanced Na(+) channel intermediate inactivation in Brugada syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
Transmural dispersion of repolarization and arrhythmogenicity: the Brugada syndrome versus the long QT syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 September 2017
The molecular genetics of the long QT syndrome: genes causing fainting and sudden death
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Right bundle-branch block and ST-segment elevation in leads V1 through V3: a marker for sudden death in patients without demonstrable structural heart disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Arrhythmogenic marker for the sudden unexplained death syndrome in Thai men.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Pharmacological targeting of long QT mutant sodium channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Andersen's syndrome: potassium-sensitive periodic paralysis, ventricular ectopy, and dysmorphic features
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Catecholaminergic polymorphic ventricular tachycardia in children. A 7-year follow-up of 21 patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Molecular mechanism for an inherited cardiac arrhythmia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Delayed afterdepolarizations in heart muscle: mechanisms and relevance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
Cellular mechanisms of early afterdepolarizations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 September 2017
In vivo studies of Scn5a+/- mice modeling Brugada syndrome demonstrate both conduction and repolarization abnormalities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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31 May 2018
Increased right ventricular repolarization gradients promote arrhythmogenesis in a murine model of Brugada syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
31 May 2018
Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
31 May 2018
Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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31 May 2018
Sudden death among Southeast Asian refugees. An unexplained nocturnal phenomenon
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
31 May 2018
Structural heterogeneity promotes triggered activity, reflection and arrhythmogenesis in cardiomyocyte monolayers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Local depolarization abnormalities are the dominant pathophysiologic mechanism for type 1 electrocardiogram in brugada syndrome a study of electrocardiograms, vectorcardiograms, and body surface potential maps during ajmaline provocation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
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28 November 2018
Latent genetic backgrounds and molecular pathogenesis in drug-induced long-QT syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Slow and Discontinuous Conduction Conspire in Brugada Syndrome: A Right Ventricular Mapping and Stimulation Study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Andersen-Tawil syndrome: Prospective cohort analysis and expansion of the phenotype
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
New mechanism contributing to drug-induced arrhythmia: rescue of a misprocessed LQT3 mutant
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Mutation in the KCNQ1 gene leading to the short QT-interval syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Delay in right ventricular activation contributes to Brugada syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Sodium channel gene (SCN5A) mutations in 44 index patients with Brugada syndrome: different incidences in familial and sporadic disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
PIP2 binding residues of Kir2.1 are common targets of mutations causing Andersen syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Novel mechanism for Brugada syndrome: defective surface localization of an SCN5A mutant (R1432G).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
Human SCN5A gene mutations alter cardiac sodium channel kinetics and are associated with the Brugada syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3533278
retrieved
28 November 2018
QT interval prolongation as predictor of sudden death in patients with myocardial infarction
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23281413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse model
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23281413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Decreased inward rectification of Kir2.1 channels is a novel mechanism underlying the short QT syndrome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23281413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Trafficking-competent and trafficking-defective KCNJ2 mutations in Andersen syndrome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23281413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mechanism of U wave and polymorphic ventricular tachycardia in a canine tissue model of Andersen-Tawil syndrome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23281413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Prevention of ventricular fibrillation episodes in Brugada syndrome by catheter ablation over the anterior right ventricular outflow tract epicardium
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23281413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Calmodulin kinase inhibition prevents development of the arrhythmogenic transient inward current
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23281413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Frank-Starling relationship: long on importance, short on mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1172%2FJCI62928
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1172/JCI62928
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4906852
OpenCitations bibliographic resource ID
4906852
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4906852
PMC publication ID
3533278
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4906852
PubMed publication ID
23281413
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4906852
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