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iPSC-derived neurons as a higher-throughput readout for autism: promises and pitfalls
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title
iPSC-derived neurons as a higher-throughput readout for autism: promises and pitfalls
(English)
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PubMed
main subject
autism
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author
Isaac Kohane
series ordinal
6
object named as
Isaac S. Kohane
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Crossref
author name string
Daria Prilutsky
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1
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Crossref
Nathan P. Palmer
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2
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Crossref
Niklas Smedemark-Margulies
series ordinal
3
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Thorsten M. Schlaeger
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4
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David M. Margulies
series ordinal
5
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language of work or name
English
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PubMed
publication date
February 2014
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PubMed
published in
Trends in Molecular Medicine
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PubMed
volume
20
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PubMed
issue
2
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PubMed
page(s)
91-104
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PubMed
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28 September 2017
A bioinformatic assay for pluripotency in human cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Induced pluripotent stem cells: a new tool to confront the challenge of neuropsychiatric disorders
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Transcript origin analysis identifies antigen-presenting cells as primary targets of socially regulated gene expression in leukocytes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
A functionally characterized test set of human induced pluripotent stem cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Reprogramming of human primary somatic cells by OCT4 and chemical compounds
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Induced pluripotent stem cells: epigenetic memories and practical implications.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader-Willi syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader-Willi syndromes
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Key role for gene dosage and synaptic homeostasis in autism spectrum disorders
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Murine embryonic stem cell-derived pyramidal neurons integrate into the cerebral cortex and appropriately project axons to subcortical targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Direct reprogramming of human neural stem cells by OCT4.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Marked differences in differentiation propensity among human embryonic stem cell lines
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Advances in behavioral genetics: mouse models of autism
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 September 2017
Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Creation and implications of a phenome-genome network
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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28 September 2017
Derivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
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31 May 2018
A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
31 May 2018
Large scale comparison of global gene expression patterns in human and mouse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
31 May 2018
Automatic robust neurite detection and morphological analysis of neuronal cell cultures in high-content screening
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
31 May 2018
A nonviral minicircle vector for deriving human iPS cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
31 May 2018
Retinoic acid from the meninges regulates cortical neuron generation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
31 May 2018
Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
31 May 2018
Directed differentiation of telencephalic precursors from embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
31 May 2018
Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 November 2018
CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 November 2018
Unexpected X chromosome skewing during culture and reprogramming of human somatic cells can be alleviated by exogenous telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 November 2018
Development of patient-specific neurons in schizophrenia using induced pluripotent stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 November 2018
Subregional specification of embryonic stem cell-derived ventral telencephalic tissues by timed and combinatory treatment with extrinsic signals.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 November 2018
Induction of pluripotency in human cord blood unrestricted somatic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 November 2018
Generation of cortical neurons from mouse embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 November 2018
Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117413
retrieved
28 November 2018
Endotoxin Tolerance Represents a Distinctive State of Alternative Polarization (M2) in Human Mononuclear Cells
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/24374161
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Genetics of autism spectrum disorders
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24374161
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Progress toward therapeutic potential for AFQ056 in Fragile X syndrome.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24374161
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.MOLMED.2013.11.004
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
927288
OpenCitations bibliographic resource ID
927288
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
927288
PMCID
4117413
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
927288
PubMed ID
24374161
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
927288
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