(Q26829663)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

0 references

title

The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

12 October 2019

1 reference

12 October 2019

neoplastic stem cells

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Giuseppe Basso

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

4

Francesca Pistollato

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

2

Elena Rampazzo

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Alessandro Della Puppa

series ordinal

3

object named as

Alessandro Della Puppa

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

1 reference

23 October 2011

5 references

14 March 2019

3 April 2019

25 April 2019

12 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

The Scientific World Journal

17 January 2020

published in

6 references

14 March 2019

3 April 2019

25 April 2019

12 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

11

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

1829-1841

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

17 January 2020

copyright license

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

7 April 2017

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Hypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2.

7 April 2017

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Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma

28 September 2017

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Molecular subclassification of diffuse gliomas: seeing order in the chaos

28 September 2017

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Clinical trial end points for high-grade glioma: the evolving landscape.

28 September 2017

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Glioma-initiating cells and molecular pathology: implications for therapy

28 September 2017

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28 September 2017

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Cancer stem cells in glioblastoma--molecular signaling and therapeutic targeting

28 September 2017

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Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate.

28 September 2017

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Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres

28 September 2017

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28 September 2017

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Glioblastoma cancer stem cells: heterogeneity, microenvironment and related therapeutic strategies.

28 September 2017

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Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4

28 September 2017

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28 September 2017

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Glioma cell populations grouped by different cell type markers drive brain tumor growth

28 September 2017

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Potential therapeutic implications of cancer stem cells in glioblastoma

28 September 2017

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28 September 2017

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A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha

28 September 2017

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Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells

28 September 2017

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28 September 2017

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Hypoxia-inducible factors in stem cells and cancer

28 September 2017

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The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas

28 September 2017

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The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

28 September 2017

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Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells

28 September 2017

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Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

28 September 2017

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Cancer stem cells and their niche

28 September 2017

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Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution

28 September 2017

1 reference

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Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy

28 September 2017

1 reference

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Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions

28 September 2017

1 reference

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Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity

28 September 2017

1 reference

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Glioblastoma and stem cells

28 September 2017

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Hypoxia-regulated protein expression, patient characteristics, and preoperative imaging as predictors of survival in adults with glioblastoma multiforme

28 September 2017

1 reference

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Hypoxia-inducible factor 1 and cancer pathogenesis

28 September 2017

1 reference

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Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction

28 September 2017

1 reference

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Regional hypoxia in glioblastoma multiforme quantified with [18F]fluoromisonidazole positron emission tomography before radiotherapy: correlation with time to progression and survival

28 September 2017

1 reference

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Location, location, location: the cancer stem cell niche

28 September 2017

1 reference

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Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies

28 September 2017

1 reference

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The role of oxygen availability in embryonic development and stem cell function

28 September 2017

1 reference

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PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

28 September 2017

1 reference

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Differential regulation of hypoxia-induced CXCR4 triggering during B-cell development and lymphomagenesis

28 September 2017

1 reference

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Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Silencing of hypoxia inducible factor-1alpha by RNA interference attenuates human glioma cell growth in vivo.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Dynamics of tumor hypoxia measured with bioreductive hypoxic cell markers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

The human brain subventricular zone: stem cells in this niche and its organization.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Tumor microenvironment: the role of the tumor stroma in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

28 September 2017

Brain tumour stem cells

1 reference

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HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Hypoxia requires notch signaling to maintain the undifferentiated cell state

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

The role of p53 in hypoxia-induced apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

The role of hypoxia-induced factors in tumor progression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Hypoxia promotes murine bone-marrow-derived stromal cell migration and tube formation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Pharmacokinetics of the carmustine implant

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Oxidative metabolism and the detection of neuronal activation via imaging.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Modeling pO(2) distributions in the bone marrow hematopoietic compartment. I. Krogh's model

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Oxygen tension controls the expansion of human CNS precursors and the generation of astrocytes and oligodendrocytes.

28 September 2017

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Low atmospheric oxygen avoids maturation, senescence and cell death of murine mesencephalic neural precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Engraftment of sorted/expanded human central nervous system stem cells from fetal brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Hypoxia-inducible factor-1 alpha, in association with TWIST2 and SNIP1, is a critical prognostic factor in patients with tongue squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Expressions of hypoxia-inducible factor-1α and hexokinase-II in gastric adenocarcinoma: the impact on prognosis and correlation to clinicopathologic features.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Hypoxia and HIF1alpha repress the differentiative effects of BMPs in high-grade glioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Diversity of cytogenetic and pathohistologic profiles in glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Making a tumour's bed: glioblastoma stem cells and the vascular niche.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

A crosstalk between the Wnt and the adhesion-dependent signaling pathways governs the chemosensitivity of acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Pigment epithelium-derived factor is a niche signal for neural stem cell renewal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Gliomagenesis and neural stem cells: Key role of hypoxia and concept of tumor "neo-niche".

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Association of stem cell marker CD133 expression with dissemination of glioblastomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

A specialized vascular niche for adult neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1100%2F2011%2F736480

Isolation and expansion of regionally defined human glioblastoma cells in vitro.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

HIF-1alpha is a prognostic marker in oral squamous cell carcinomas

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Does hypoxia really control tumor growth?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Involvement of hypoxia-inducible factor 1 in human cancer

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217608

Association of hypoxia-inducible factor 1-alpha gene polymorphisms and colorectal cancer prognosis

28 November 2018

1 reference

12 December 2020

The nature of stem cells: state rather than entity

1 reference

12 December 2020

The effect of oxygen on biochemical networks and the evolution of complex life

1 reference

12 December 2020

Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen

1 reference

12 December 2020

The role of hypoxia in the maintenance of hematopoietic stem cells

1 reference

12 December 2020

Identification of A2B5+CD133- tumor-initiating cells in adult human gliomas

1 reference

12 December 2020

Identifiers

DOI

10.1100/2011/736480

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22125441%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

2 references