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Molecular views of Arf-like small GTPases in cilia and ciliopathies
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title
Molecular views of Arf-like small GTPases in cilia and ciliopathies
(English)
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stated in
PubMed
author name string
Qing Zhang
series ordinal
1
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Crossref
Jinghua Hu
series ordinal
2
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Crossref
Kun Ling
series ordinal
3
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
10 September 2013
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stated in
PubMed
published in
Experimental Cell Research
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stated in
PubMed
volume
319
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PubMed
issue
15
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PubMed
page(s)
2316-22
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PubMed
cites work
Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes
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An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium
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UNC119 is required for G protein trafficking in sensory neurons
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Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy
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The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia
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Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans
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Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling
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A BBSome subunit links ciliogenesis, microtubule stability, and acetylation
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Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndrome
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The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3
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PubMed Central
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HEF1-dependent Aurora A activation induces disassembly of the primary cilium
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PubMed Central
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A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
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The Ciliopathies: An Emerging Class of Human Genetic Disorders
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Bardet-Biedl syndrome genes are important in retrograde intracellular trafficking and Kupffer's vesicle cilia function
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Comparative genomic analysis identifies an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3)
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Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3
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Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo
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Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?
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ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting
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PubMed Central
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7 April 2017
Arl3 and RP2 mediated assembly and traffic of membrane associated cilia proteins.
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PubMed Central
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7 April 2017
The emerging role of Arf/Arl small GTPases in cilia and ciliopathies
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7 April 2017
The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis
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PubMed Central
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7 April 2017
Functional coordination of intraflagellar transport motors.
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Arf-like GTPases: not so Arf-like after all.
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Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome
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ADP-ribosylation factor (ARF)-like 3, a new member of the ARF family of GTP-binding proteins cloned from human and rat tissues
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Intraflagellar transport
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PubMed Central
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ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins
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GEFs: structural basis for their activation of small GTP-binding proteins
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7 April 2017
Intraflagellar transport is required for the vectorial movement of TRPV channels in the ciliary membrane
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PubMed Central
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7 April 2017
GAP control: regulating the regulators of small GTPases
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PubMed Central
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7 April 2017
Functional characterization of putative cilia genes by high-content analysis
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PubMed Central
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7 April 2017
Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742637
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7 April 2017
ADP-ribosylation factor-like 3 is involved in kidney and photoreceptor development
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PubMed Central
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7 April 2017
Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742637
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7 April 2017
The graded response to Sonic Hedgehog depends on cilia architecture
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742637
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7 April 2017
The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway
1 reference
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PubMed Central
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7 April 2017
The delta subunit of rod specific cyclic GMP phosphodiesterase, PDE delta, interacts with the Arf-like protein Arl3 in a GTP specific manner
1 reference
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PubMed Central
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7 April 2017
The primary cilium: a signalling centre during vertebrate development
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742637
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7 April 2017
The primary cilium as the cell's antenna: signaling at a sensory organelle
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PubMed Central
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7 April 2017
Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis
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PubMed Central
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7 April 2017
HDAC6 inhibition restores ciliary expression and decreases tumor growth
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PubMed Central
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28 September 2017
SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors
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PubMed Central
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28 September 2017
The ciliopathies: a transitional model into systems biology of human genetic disease
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28 September 2017
Disrupted dorsal neural tube BMP signaling in the cilia mutant Arl13b hnn stems from abnormal Shh signaling
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PubMed Central
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28 September 2017
Small GTPases and cilia
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PubMed Central
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28 September 2017
Planar cell polarity acts through septins to control collective cell movement and ciliogenesis.
1 reference
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PubMed Central
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28 September 2017
Clinical and molecular features of Joubert syndrome and related disorders
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PubMed Central
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28 September 2017
Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy
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PubMed Central
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28 September 2017
HDAC6: a key regulator of cytoskeleton, cell migration and cell-cell interactions
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PubMed Central
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28 September 2017
Deletion of PrBP/delta impedes transport of GRK1 and PDE6 catalytic subunits to photoreceptor outer segments.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742637
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28 September 2017
Molecular basis of polycystic kidney disease: PKD1, PKD2 and PKHD1.
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28 September 2017
GTPase activating proteins: critical regulators of intracellular signaling
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28 September 2017
Potential drug targets: small GTPases that regulate leukocyte function
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742637
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28 September 2017
Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742637
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31 May 2018
A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans
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31 May 2018
Exome sequencing identifies mutations in LZTFL1, a BBSome and smoothened trafficking regulator, in a family with Bardet--Biedl syndrome with situs inversus and insertional polydactyly.
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PubMed Central
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28 November 2018
A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney
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28 November 2018
Photoreceptor cGMP Phosphodiesterase δ Subunit (PDEδ) Functions as a Prenyl-binding Protein
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28 November 2018
LdARL-3A, a Leishmania promastigote-specific ADP-ribosylation factor-like protein, is essential for flagellum integrity.
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PubMed Central
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28 November 2018
A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.03.024
retrieved
7 January 2021
Identifiers
DOI
10.1016/J.YEXCR.2013.03.024
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1870100
OpenCitations bibliographic resource ID
1870100
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1870100
PMCID
3742637
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1870100
PubMed ID
23548655
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1870100
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