(Q26830704)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

The hypocretins/orexins: integrators of multiple physiological functions (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Luis de Lecea

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

author name string

Zhian Hu

series ordinal

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

language of work or name

1 reference

1 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

27 February 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

volume

171

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

issue

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

page(s)

332-350

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

Physiology of the orexinergic/hypocretinergic system: a revisit in 2012

27 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin/hypocretin and histamine: distinct roles in the control of wakefulness demonstrated using knock-out mouse models

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Role of lateral hypothalamic orexin neurons in reward processing and addiction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The orexin system regulates alcohol-seeking in rats

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

SB-334867-A: the first selective orexin-1 receptor antagonist

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Multiple roles for orexin/hypocretin in addiction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

To eat or to sleep? Orexin in the regulation of feeding and wakefulness

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin A stimulates cortisol secretion from human adrenocortical cells through activation of the adenylate cyclase-dependent signaling cascade

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexins stimulate glucocorticoid secretion from cultured rat and human adrenocortical cells, exclusively acting via the OX1 receptor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Preproorexin and orexin receptors are expressed in cortisol-secreting adrenocortical adenomas, and orexins stimulate in vitro cortisol secretion and growth of tumor cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Novel substituted 4-phenyl-[1,3]dioxanes: potent and selective orexin receptor 2 (OX(2)R) antagonists

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Functional magnetic resonance imaging reveals different neural substrates for the effects of orexin-1 and orexin-2 receptor antagonists

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Postsynaptic excitation of prefrontal cortical pyramidal neurons by hypocretin-1/orexin A through the inhibition of potassium currents

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Pattern of orexin expression and direct biological actions of orexin-a in rat testis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Localization of orexins and their receptors in the rat olfactory system: possible modulation of olfactory perception by a neuropeptide synthetized centrally or locally

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin-A augments voltage-gated Ca2+ currents and synergistically increases growth hormone (GH) secretion with GH-releasing hormone in primary cultured ovine somatotropes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypothalamic regulation of sleep and circadian rhythms

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Neurons containing hypocretin (orexin) project to multiple neuronal systems

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The Concise Guide to PHARMACOLOGY 2013/14: overview

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Mechanism for Hypocretin-mediated sleep-to-wake transitions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin-A induces anxiety-like behavior through interactions with glutamatergic receptors in the bed nucleus of the stria terminalis of rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Promotion of sleep by suvorexant-a novel dual orexin receptor antagonist

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin receptor 2 expression in the posterior hypothalamus rescues sleepiness in narcoleptic mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Decision making in narcolepsy with cataplexy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Direct inhibition of hypocretin/orexin neurons in the lateral hypothalamus by nociceptin/orphanin FQ blocks stress-induced analgesia in rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

28 September 2017

Sleep state switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Intrathecal orexin A increases sympathetic outflow and respiratory drive, enhances baroreflex sensitivity and blocks the somato-sympathetic reflex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Circadian and homeostatic regulation of structural synaptic plasticity in hypocretin neurons

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Direct innervation and modulation of orexin neurons by lateral hypothalamic LepRb neurons

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Intact learning and memory in rats following treatment with the dual orexin receptor antagonist almorexant

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Elevated sleep quality and orexin receptor mRNA in obesity-resistant rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexins and gastrointestinal functions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypocretins regulate the anxiogenic-like effects of nicotine and induce reinstatement of nicotine-seeking behavior

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

A key role for orexin in panic anxiety.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Thermal nociception is decreased by hypocretin-1 and an adenosine A1 receptor agonist microinjected into the pontine reticular formation of Sprague Dawley rat

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The role of hypocretin in driving arousal and goal-oriented behaviors.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Convergent actions of orexin/hypocretin and CRF on dopamine neurons: Emerging players in addiction.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin A-induced extracellular calcium influx in prefrontal cortex neurons involves L-type calcium channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexins (hypocretins) actions on the GHRH/somatostatin-GH axis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypocretin/orexin in arousal and stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin A/hypocretin-1 selectively promotes motivation for positive reinforcers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Sleep homeostasis modulates hypocretin-mediated sleep-to-wake transitions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Role of orexin/hypocretin in dependence and addiction.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypocretin-2 saporin lesions of the ventrolateral periaquaductal gray (vlPAG) increase REM sleep in hypocretin knockout mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Nutritional status modulates behavioural and olfactory bulb Fos responses to isoamyl acetate or food odour in rats: roles of orexins and leptin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Role of the ventromedial hypothalamic orexin-1 receptors in regulation of gastric Acid secretion in conscious rats.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Melanin-concentrating hormone neurons discharge in a reciprocal manner to orexin neurons across the sleep-wake cycle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The brain hypocretins and their receptors: mediators of allostatic arousal.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Memory enhancement with event-related stimulation of the rostral intralaminar thalamic nuclei

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Stress, the hippocampus, and epilepsy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The hypocretins as sensors for metabolism and arousal.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin-A hyperphagia: hindbrain participation in consummatory feeding responses.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Sleep and metabolism: shared circuits, new connections

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypothalamic orexins/hypocretins as regulators of breathing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin-A modulates glutamatergic NMDA-dependent spinal reflex potentiation via inhibition of NR2B subunit

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Physiological arousal: a role for hypothalamic systems

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Addiction and arousal: the hypocretin connection.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

An essential role for orexins in emergence from general anesthesia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Systemic and nasal delivery of orexin-A (Hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Eating disorder and metabolism in narcoleptic patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Food-induced expression of orexin receptors in rat duodenal mucosa regulates the bicarbonate secretory response to orexin-A.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Control of hypothalamic orexin neurons by acid and CO2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Sleep circuitry and the hypnotic mechanism of GABAA drugs.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Study of orexins signal transduction pathways in rat olfactory mucosa and in olfactory sensory neurons-derived cell line Odora: multiple orexin signalling pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Promotion of sleep by targeting the orexin system in rats, dogs and humans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Integration of feeding and spontaneous physical activity: role for orexin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Stress and arousal: the corticotrophin-releasing factor/hypocretin circuitry.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Afferents to the orexin neurons of the rat brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Metabolic state signalling through central hypocretin/orexin neurons.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Concomitant loss of dynorphin, NARP, and orexin in narcolepsy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Non-sleep effects of hypocretin/orexin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin A in the nucleus accumbens stimulates feeding and locomotor activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

A polymorphism of the hypocretin receptor 2 gene is associated with cluster headache

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Electrical signaling in central orexin/hypocretin circuits: tuning arousal and appetite to fit the environment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Behavioral state instability in orexin knock-out mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The orexin/hypocretin system: a critical regulator of neuroendocrine and autonomic function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Central orexin A has site-specific effects on luteinizing hormone release in female rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypothalamic orexin neurons regulate arousal according to energy balance in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The hypocretins: setting the arousal threshold

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Neuronal effects of orexins: relevant to sympathetic and cardiovascular functions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Arousal effect of orexin A depends on activation of the histaminergic system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Fos expression in orexin neurons varies with behavioral state.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX1) receptors, with downstream 5-HT2C receptor involvement

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin-A suppresses the pulsatile secretion of luteinizing hormone via beta-endorphin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Reduced number of hypocretin neurons in human narcolepsy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexins suppress catecholamine synthesis and secretion in cultured PC12 cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypothalamic hypocretin (orexin): robust innervation of the spinal cord

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Differential roles of orexin receptor-1 and -2 in the regulation of non-REM and REM sleep

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Molecular annotation of integrative feeding neural circuits

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Narcoleptic orexin receptor knockout mice express enhanced cholinergic properties in laterodorsal tegmental neurons

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Changes in emotional behavior produced by orexin microinjections in the paraventricular nucleus of the thalamus.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Histamine-1 receptor is not required as a downstream effector of orexin-2 receptor in maintenance of basal sleep/wake states

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Regulation of synaptic efficacy in hypocretin/orexin-containing neurons by melanin concentrating hormone in the lateral hypothalamus

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Vigilance state-dependent attenuation of hypercapnic chemoreflex and exaggerated sleep apnea in orexin knockout mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Stimulatory effect of endogenous orexin A on gastric emptying and acid secretion independent of gastrin.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Centrally administered orexin A increases motivation for sweet pellets in rats

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexins modulate the growth of cultured rat adrenocortical cells, acting through type 1 and type 2 receptors coupled to the MAPK p42/p44- and p38-dependent cascades

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin 1 receptor messenger ribonucleic acid expression and stimulation of testosterone secretion by orexin-A in rat testis.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypothalamus-brain stem circuitry responsible for vagal efferent signaling to the pancreas evoked by hypoglycemia in rat.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Anti-mechanical allodynic effect of intrathecal and intracerebroventricular injection of orexin-A in the rat neuropathic pain model

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Analgesic effect of intrathecally administered orexin-A in the rat formalin test and in the rat hot plate test

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Wake-promoting and sleep-suppressing actions of hypocretin (orexin): basal forebrain sites of action

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Microdialysis perfusion of orexin-A in the basal forebrain increases wakefulness in freely behaving rats.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Central orexin-A activates hypothalamic-pituitary-adrenal axis and stimulates hypothalamic corticotropin releasing factor and arginine vasopressin neurones in conscious rats

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexins stimulate corticosterone secretion of rat adrenocortical cells, through the activation of the adenylate cyclase-dependent signaling cascade

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Food intake elicited by central administration of orexins/hypocretins: identification of hypothalamic sites of action.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Functional inactivation of orexin 1 receptors in CA1 region impairs acquisition, consolidation and retrieval in Morris water maze task.

31 May 2018

1 reference

The selective orexin 1 receptor antagonist SB-334867-A impairs acquisition and consolidation but not retrieval of spatial memory in Morris water maze.

21 January 2018

1 reference

The effect of antagonization of orexin 1 receptors in CA1 and dentate gyrus regions on memory processing in passive avoidance task.

21 January 2018

1 reference

Orexin-A (hypocretin-1) impairs Morris water maze performance and CA1-Schaffer collateral long-term potentiation in rats.

21 January 2018

1 reference

Evidence for a modulatory role of orexin A on the nitrergic neurotransmission in the mouse gastric fundus

21 January 2018

1 reference

Orexin A attenuates unconditioned sexual motivation in male rats

21 January 2018

1 reference

Olfactory dysfunction in patients with narcolepsy with cataplexy is restored by intranasal Orexin A (Hypocretin-1).

21 January 2018

1 reference

Orexin axons in the rat ventral tegmental area synapse infrequently onto dopamine and gamma-aminobutyric acid neurons.

21 January 2018

1 reference

Orexin-B modulates luteinizing hormone and growth hormone secretion from porcine pituitary cells in culture

21 January 2018

1 reference

Differential modulation of nociceptive dural input to [hypocretin] orexin A and B receptor activation in the posterior hypothalamic area.

21 January 2018

1 reference

Orexins (hypocretins) directly excite tuberomammillary neurons

21 January 2018

1 reference

Opposite effects of noradrenaline and acetylcholine upon hypocretin/orexin versus melanin concentrating hormone neurons in rat hypothalamic slices

21 January 2018

1 reference

Orexin-A, an hypothalamic peptide with analgesic properties

21 January 2018

1 reference

Systemic and intrabasalis administration of the orexin-1 receptor antagonist, SB-334867, disrupts attentional performance in rats.

21 January 2018

1 reference

Hypothalamic-pituitary-adrenal responses to centrally administered orexin-A are suppressed in pregnant rats.

21 January 2018

1 reference

Gastroprotective action of orexin-A against stress-induced gastric damage is mediated by endogenous prostaglandins, sensory afferent neuropeptides and nitric oxide

21 January 2018

1 reference

Effect of orexin-a on ischemia-reperfusion-induced gastric damage in rats

21 January 2018

1 reference

Central orexin-A increases gastric motility in rats

21 January 2018

1 reference

Olfactory dysfunction in narcolepsy with and without cataplexy

21 January 2018

1 reference

Decreased plasma levels of orexin-A in sleep apnea

21 January 2018

1 reference

Circulating triglycerides impact on orexigenic peptides and neuronal activity in hypothalamus

21 January 2018

1 reference

Inhibitory effects of an orexin-2 receptor antagonist on orexin A- and stress-induced ACTH responses in conscious rats.

21 January 2018

1 reference

The role of orexin-A in food motivation, reward-based feeding behavior and food-induced neuronal activation in rats

21 January 2018

1 reference

Cardiac effects of hypocretin-1 in nucleus ambiguus

21 January 2018

1 reference

High pain frequency in narcolepsy with cataplexy.

21 January 2018

1 reference

Convergence of circadian and sleep regulatory mechanisms on hypocretin-1.

21 January 2018

1 reference

Contribution of orexin in hypercapnic chemoreflex: evidence from genetic and pharmacological disruption and supplementation studies in mice.

21 January 2018

1 reference

Hypocretin-1 (orexin-A) facilitates inhibitory and diminishes excitatory synaptic pathways to cardiac vagal neurons in the nucleus ambiguus

21 January 2018

1 reference

Indirect projections from the suprachiasmatic nucleus to major arousal-promoting cell groups in rat: implications for the circadian control of behavioural state

21 January 2018

1 reference

Antagonism of orexin receptor-1 in the retrotrapezoid nucleus inhibits the ventilatory response to hypercapnia predominantly in wakefulness.

21 January 2018

1 reference

Effect of sodium oxybate on growth hormone secretion in narcolepsy patients and healthy controls.

21 January 2018

1 reference

Blockade of orexin-1 receptors attenuates orexin-2 receptor antagonism-induced sleep promotion in the rat.

21 January 2018

1 reference

Activation of Orexin B receptors in the pontine Kölliker-Fuse nucleus modulates pre-inspiratory hypoglossal motor activity in rat.

21 January 2018

1 reference

Inhibitory effect of exogenous orexin a on gastric emptying, plasma leptin, and the distribution of orexin and orexin receptors in the gut and pancreas in man.

21 January 2018

1 reference

Expression of hypothalamic neuropeptides after acute TCDD treatment and distribution of Ah receptor repressor

21 January 2018

1 reference

Short fasting dramatically decreases rat duodenal secretory responsiveness to orexin A but not to VIP or melatonin

21 January 2018

1 reference

Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation.

21 January 2018

1 reference

Hypocretin/orexin contributes to the expression of some but not all forms of stress and arousal

21 January 2018

1 reference

Suppressive action of orexin A on pulsatile luteinizing hormone secretion is potentiated by a low dose of estrogen in ovariectomized rats

21 January 2018

1 reference

The wake-promoting hypocretin/orexin neurons change their response to noradrenaline after sleep deprivation.

21 January 2018

1 reference

Respiratory regulation in narcolepsy.

21 January 2018

1 reference

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

21 January 2018

1 reference

A role for lateral hypothalamic orexin neurons in reward seeking

21 January 2018

1 reference

A selective orexin-1 receptor antagonist reduces food consumption in male and female rats.

21 January 2018

1 reference

Orexin receptor antagonism for treatment of insomnia: a randomized clinical trial of suvorexant.

21 January 2018

1 reference

Plasma orexin-A is lower in patients with narcolepsy.

21 January 2018

1 reference

Effects of central hypocretin-1 administration on hemodynamic responses in young-adult and middle-aged rats

21 January 2018

1 reference

Input organization and plasticity of hypocretin neurons: possible clues to obesity's association with insomnia.

21 January 2018

1 reference

Fasting stimulates tuberoinfundibular dopaminergic neuronal activity and inhibits prolactin secretion in oestrogen-primed ovariectomized rats: involvement of orexin A and neuropeptide Y.

21 January 2018

1 reference

Prefrontal cortex-projecting glutamatergic thalamic paraventricular nucleus-excited by hypocretin: a feedforward circuit that may enhance cognitive arousal

21 January 2018

1 reference

Orexins depolarize rostral ventrolateral medulla neurons and increase arterial pressure and heart rate in rats mainly via orexin 2 receptors

21 January 2018

1 reference

The type 2 corticotrophin-releasing hormone receptor mediates orexin A-induced luteinising hormone suppression in ovariectomised rats.

21 January 2018

1 reference

Effects of orexin-A on memory processing.

21 January 2018

1 reference

The role of neuropeptide Y in orexin-induced hypothalamic-pituitary-adrenal activation.

21 January 2018

1 reference

Changes in rat olfactory detection performance induced by orexin and leptin mimicking fasting and satiation.

21 January 2018

1 reference

Stimulation of catecholamine synthesis by orexin-A in bovine adrenal medullary cells through orexin receptor 1.

21 January 2018

1 reference

Attenuated defense response and low basal blood pressure in orexin knockout mice

21 January 2018

1 reference

Gastric acid secretion induced by paraventricular nucleus microinjection of orexin A is mediated through activation of neuropeptide Yergic system.

21 January 2018

1 reference

Orexin synthesis and response in the gut.

21 January 2018

1 reference

Orexin A (hypocretin 1) injected into hypothalamic paraventricular nucleus and spontaneous physical activity in rats

21 January 2018

1 reference

Neuropeptide Y mediates orexin A-mediated suppression of pulsatile gonadotropin-releasing hormone secretion in ovariectomized rats.

21 January 2018

1 reference

Involvement of orexin-A on micturition reflex in normal and cyclophosphamide-induced cystitis bladder in rat.

21 January 2018

1 reference

A significant participation of orexin-A, a potent orexigenic peptide, in the preovulatory luteinizing hormone and prolactin surges in the rat.

21 January 2018

1 reference

Dynamics of the pituitary-adrenal ensemble in hypocretin-deficient narcoleptic humans: blunted basal adrenocorticotropin release and evidence for normal time-keeping by the master pacemaker.

21 January 2018

1 reference

Pulsatile LH release is diminished, whereas FSH secretion is normal, in hypocretin-deficient narcoleptic men.

21 January 2018

1 reference

Altered setting of the pituitary-thyroid ensemble in hypocretin-deficient narcoleptic men.

21 January 2018

1 reference

Role of orexin receptors in the nucleus accumbens in dopamine-dependent turning behaviour of rats

21 January 2018

1 reference

Orexins in rat dorsal motor nucleus of the vagus potently stimulate gastric motor function

21 January 2018

1 reference

Effects of serotonin on perifornical-lateral hypothalamic area neurons in rat.

21 January 2018

1 reference

Hypocretin and nicotine excite the same thalamocortical synapses in prefrontal cortex: correlation with improved attention in rat.

21 January 2018

1 reference

Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle.

21 January 2018

1 reference

The modulation of orexin A on HCN currents of pyramidal neurons in mouse prelimbic cortex

21 January 2018

1 reference

Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system

21 January 2018

1 reference

Orexin-A acts on the paraventricular nucleus of the midline thalamus to inhibit locomotor activity in rats.

21 January 2018

1 reference

Orexin-A and respiration in a rat model of smoke-induced chronic obstructive pulmonary disease.

21 January 2018

1 reference

Orexin-A regulates growth hormone-releasing hormone mRNA content in a nucleus-specific manner and somatostatin mRNA content in a growth hormone-dependent fashion in the rat hypothalamus

21 January 2018

1 reference

Electrical inhibition of identified anorexigenic POMC neurons by orexin/hypocretin.

21 January 2018

1 reference

Differential expression of orexin receptors 1 and 2 in the rat brain.

21 January 2018

1 reference

Central orexin-A augments sympathoadrenal outflow in conscious rabbits

21 January 2018

1 reference

Involvement of the serotonergic system in orexin-induced behavioral alterations in rats

21 January 2018

1 reference

SB-334867-A, a selective orexin-1 receptor antagonist, enhances taste aversion learning and blocks taste preference learning in rats.

21 January 2018

1 reference

Delta-like 1 homologue is a hypothalamus-enriched protein that is present in orexin-containing neurones of the lateral hypothalamic area

21 January 2018

1 reference

Effects of lateral preoptic area application of orexin-A on sleep-wakefulness

21 January 2018

1 reference

Behavioral correlates of activity in identified hypocretin/orexin neurons

21 January 2018

1 reference

Central Orexin-A stimulates pancreatic exocrine secretion via the vagus

21 January 2018

1 reference

Orexin a stimulates hypothalamic-pituitary-adrenal (HPA) axis function, but not food intake, in the absence of full hypothalamic NPY-ergic activity

21 January 2018

1 reference

Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose-responsive neurons to regulate Ca 2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus

21 January 2018

1 reference

A role for hypocretin (orexin) in male sexual behavior.

21 January 2018

1 reference

Localization and effects of orexin on fasting motility in the rat duodenum.

21 January 2018

1 reference

Hypocretin (orexin) deficiency in human narcolepsy.

21 January 2018

1 reference

Decreased brain histamine content in hypocretin/orexin receptor-2 mutated narcoleptic dogs

21 January 2018

1 reference

Central orexin-A increases colonic motility in conscious rats

21 January 2018

1 reference

Cardiovascular responses to hypocretin-1 in nucleus ambiguus of the ovariectomized female rat.

21 January 2018

1 reference

Cardiovascular effects of hypocretin-1 in nucleus of the solitary tract

21 January 2018

1 reference

Somatotropic axis in hypocretin-deficient narcoleptic humans: altered circadian distribution of GH-secretory events.

21 January 2018

1 reference

Excitatory effects of hypocretin-1 (orexin-A) in the trigeminal motor nucleus are reversed by NMDA antagonism

21 January 2018

1 reference

Physiological properties of hypothalamic MCH neurons identified with selective expression of reporter gene after recombinant virus infection

21 January 2018

1 reference

Neuropeptide Y counteracts the anorectic and weight reducing effects of ciliary neurotropic factor

21 January 2018

1 reference

Altered sleep homeostasis after restraint stress in 5-HTT knock-out male mice: a role for hypocretins.

21 January 2018

1 reference

Selective expression of Narp, a secreted neuronal pentraxin, in orexin neurons

21 January 2018

1 reference

Neuroendocrinology briefings 12: The maternal brain

21 January 2018

1 reference

Orexin A interactions in the hypothalamo-pituitary gonadal axis

21 January 2018

1 reference

Chronic intraparaventricular nuclear administration of orexin A in male rats does not alter thyroid axis or uncoupling protein-1 in brown adipose tissue

21 January 2018

1 reference

Expression of orexin A and its receptor 1 in the bovine urethroprostatic complex.

21 January 2018

1 reference

Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: possible involvement of central orexins on stress-activated central CRF n

21 January 2018

1 reference

Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice

21 January 2018

1 reference

Cardiovascular regulatory actions of the hypocretins in brain.

21 January 2018

1 reference

Orexin actions in hypothalamic paraventricular nucleus: physiological consequences and cellular correlates.

21 January 2018

1 reference

Orexins/hypocretins cause sharp wave- and theta-related synaptic plasticity in the hippocampus via glutamatergic, gabaergic, noradrenergic, and cholinergic signaling.

21 January 2018

1 reference

Orexins/hypocretins control bistability of hippocampal long-term synaptic plasticity through co-activation of multiple kinases.

21 January 2018

1 reference

Orexin A suppresses in vivo GH secretion

21 January 2018

1 reference

Effects of leptin and orexin-A on food intake and feeding related hypothalamic neurons.

21 January 2018

1 reference

Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system.

21 January 2018

1 reference

Both orexin receptors are expressed in rat ovaries and fluctuate with the estrous cycle: effects of orexin receptor antagonists on gonadotropins and ovulation.

21 January 2018

1 reference

Orexin-saporin lesions of the medial septum impair spatial memory.

21 January 2018

1 reference

Microinjection of orexin into the rat nucleus tractus solitarius causes increases in blood pressure

21 January 2018

1 reference

Cardiovascular actions of orexin-A in the rat subfornical organ.

21 January 2018

1 reference

Signaling pathways of hypocretin-1 actions on pyramidal neurons in the rat prefrontal cortex.

21 January 2018

1 reference

Olfactory dysfunction in patients with narcolepsy with and without REM sleep behaviour disorder.

21 January 2018

1 reference

Evidence of roles of central alpha1-adrenoceptors and epinephrine in orexin A-induced hyperactivity in mice

21 January 2018

1 reference

Orexins and adipoinsular axis function in the rat.

21 January 2018

1 reference

Effects of orexin on the laterodorsal tegmental neurones.

21 January 2018

1 reference

Expression of orexin-A and orexin receptors in the kidney and the presence of orexin-A-like immunoreactivity in human urine.

21 January 2018

1 reference

Stimulation of gastric acid secretion by centrally administered orexin-A in conscious rats.

21 January 2018

1 reference

Changes in the excitability of hindlimb motoneurons during muscular atonia induced by stimulating the pedunculopontine tegmental nucleus in cats.

21 January 2018

1 reference

Orexinergic projections to the cat midbrain mediate alternation of emotional behavioural states from locomotion to cataplexy

21 January 2018

1 reference

The action of orexin A on passive avoidance learning. Involvement of transmitters

21 January 2018

1 reference

Ventilatory long-term facilitation in mice can be observed during both sleep and wake periods and depends on orexin

21 January 2018

1 reference

Peptides that regulate food intake: regional, metabolic, and circadian specificity of lateral hypothalamic orexin A feeding stimulation

21 January 2018

1 reference

Orexin A-induced feeding is augmented by caloric challenge.

21 January 2018

1 reference

Orexin-A infusion in the locus ceruleus triggers norepinephrine (NE) release and NE-induced long-term potentiation in the dentate gyrus.

21 January 2018

1 reference

Effects on sleep and wakefulness of the injection of hypocretin-1 (orexin-A) into the laterodorsal tegmental nucleus of the cat.

21 January 2018

1 reference

A selective orexin-1 receptor antagonist, SB334867, blocks 2-DG-induced gastric acid secretion in rats.

21 January 2018

1 reference

Intracisternal injection of orexin-A prevents ethanol-induced gastric mucosal damage in rats.

21 January 2018

1 reference

Activation of spinal orexin-1 receptor produces anti-allodynic effect in the rat carrageenan test

21 January 2018

1 reference

Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight

21 January 2018

1 reference

Regulation of orexin neurons by the monoaminergic and cholinergic systems.

21 January 2018

1 reference

Orexin directly excites orexin neurons through orexin 2 receptor

21 January 2018

1 reference

Orexin-A excites pyramidal neurons in layer 2/3 of the rat prefrontal cortex

21 January 2018

1 reference

Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities.

21 January 2018

1 reference

A role for orexin in central vestibular motor control.

21 January 2018

1 reference

Orexin signaling in the ventral tegmental area is required for high-fat appetite induced by opioid stimulation of the nucleus accumbens

21 January 2018

1 reference

The role of orexin A in the control of prolactin and growth hormone secretions in sheep--in vitro study.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Plasma orexin A, orexin B, leptin, neuropeptide Y (NPY) and insulin in obese women

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypothalamic substrates of reward.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Circadian and Homeostatic Regulation of Hypocretin in a Primate Model: Implications for the Consolidation of Wakefulness

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypocretinergic neurons are primarily involved in activation of the somatomotor system.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Release of hypocretin (orexin) during waking and sleep states.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Muscle tone facilitation and inhibition after orexin-a (hypocretin-1) microinjections into the medial medulla.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Orexin (hypocretin) neurons contain dynorphin.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypocretin/orexin suppresses corticotroph responsiveness in vitro

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Increased and decreased muscle tone with orexin (hypocretin) microinjections in the locus coeruleus and pontine inhibitory area.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Prolonged orexin administration stimulates steroid-hormone secretion, acting directly on the rat adrenal gland

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904255

Normal plasma levels of orexin A (hypocretin-1) in narcoleptic patients

28 November 2018

1 reference

12 December 2020

Feeding and activity induced by orexin A in the lateral hypothalamus in rats

1 reference

12 December 2020

Decreased plasma orexin-A levels in obese individuals

1 reference

12 December 2020

Orexin A affects ascending contraction depending on downstream cholinergic neurons and descending relaxation through independent pathways in mouse jejunum

1 reference

12 December 2020

Effects of orexin A on thyrotropin-releasing hormone and thyrotropin secretion in rats

1 reference

12 December 2020

Sympathetic and cardiovascular actions of orexins in conscious rats

1 reference

12 December 2020

Acute orexin effects on insulin secretion in the rat: in vivo and in vitro studies

1 reference

12 December 2020

Orexin-induced food intake involves neuropeptide Y pathway

1 reference

12 December 2020

Possible involvement of orexin in the stress reaction in rats

1 reference

12 December 2020

Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system

1 reference

12 December 2020

Effects of orexins on the hypothalamic-pituitary-adrenal system

1 reference

12 December 2020

Plasma orexin-A levels in obstructive sleep apnea-hypopnea syndrome

1 reference

12 December 2020

Central administration of orexin A suppresses basal and domperidone stimulated plasma prolactin

1 reference

12 December 2020

Immunoreactive orexin-A in human plasma

1 reference

12 December 2020

Central orexin facilitates gastric relaxation and contractility in rats

1 reference

12 December 2020

Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response

1 reference

12 December 2020

Persistent pain and stress activate pain-inhibitory orexin pathways

1 reference

12 December 2020

Orexin neurons are indispensable for stress-induced thermogenesis in mice

1 reference

12 December 2020

Activation of central orexin/hypocretin neurons by dietary amino acids

1 reference

12 December 2020

Identifiers

DOI

10.1111/BPH.12415

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24102345%20AND%20SRC:MED&resulttype=core&format=json