(Q26849351)

English

The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse

scientific article

In more languages

Statements

scholarly article

1 reference

The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse (English)

1 reference

author name string

J. P. R. Jacobsen

1

1 reference

I. O. Medvedev

2

1 reference

M. G. Caron

3

1 reference

language of work or name

1 reference

publication date

5 September 2012

1 reference

Philosophical Transactions of the Royal Society B

1 reference

367

1 reference

1601

1 reference

2444-59

1 reference

Suicidal thoughts and behavior with antidepressant treatment: reanalysis of the randomized placebo-controlled studies of fluoxetine and venlafaxine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Growth retardation and altered autonomic control in mice lacking brain serotonin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Animal models of suicide-trait-related behaviors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Serotonin-1A receptor imaging in recurrent depression: replication and literature review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Frontolimbic Serotonin 2A Receptor Binding in Healthy Subjects Is Associated with Personality Risk Factors for Affective Disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

The catecholamine hypothesis of affective disorders: a review of supporting evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

The myth of reserpine-induced depression: role in the historical development of the monoamine hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Monoaminergic neurotransmission: the history of the discovery of antidepressants from 1950s until today

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Ventricular cerebrospinal fluid monoamine transmitter and metabolite concentrations reflect human brain neurochemistry in autopsy cases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Synthesis of serotonin by a second tryptophan hydroxylase isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Biochemistry of tryptophan in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

7 April 2017

Investigating anxiety and depressive-like phenotypes in genetic mouse models of serotonin depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

The reduction of R1, a novel repressor protein for monoamine oxidase A, in major depressive disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Mechanism of acute tryptophan depletion: is it only serotonin?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Tryptophan hydroxylase-2 (TPH2) in disorders of cognitive control and emotion regulation: a perspective.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

A functional alternative splicing mutation in human tryptophan hydroxylase-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Familial risk for mood disorder and the personality risk factor, neuroticism, interact in their association with frontolimbic serotonin 2A receptor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Functional properties of missense variants of human tryptophan hydroxylase 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Serotonin and depression: pathophysiological mechanism or marketing myth?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Important messages in the 'post': recent discoveries in 5-HT neurone feedback control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5'-region are associated with bipolar affective disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Restoring melancholia in the classification of mood disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Characterization of a functional promoter polymorphism of the human tryptophan hydroxylase 2 gene in serotonergic raphe neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

The PAH gene, phenylketonuria, and a paradigm shift

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Maternal serotonin is crucial for murine embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Serotonergic vulnerability and depression: assumptions, experimental evidence and implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Functional imaging, serotonin and the suicidal brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Monoamine depletion studies: implications for antidepressant discontinuation syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Psychiatric manifestations of Creutzfeldt-Jakob disease: a 25-year analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

The genetics of depression: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Prevalence and treatment of depression in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in attention-deficit/hyperactivity disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Neuropsychiatric adverse effects of interferon-alpha: recognition and management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

From galactorrhea to osteopenia: rethinking serotonin-prolactin interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Reserpine in the treatment of anxious and depressed patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

PAHdb 2003: what a locus-specific knowledgebase can do.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Depression, IV: STAR*D treatment trial for depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Placebo response in studies of major depression: variable, substantial, and growing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Severity of depression and response to antidepressants and placebo: an analysis of the Food and Drug Administration database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Regulation of adult neurogenesis by psychotropic drugs and stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Evaluation of central serotonergic function in affective and related disorders by the fenfluramine challenge test: a critical review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Neuropsychiatric symptoms associated with hepatitis C and interferon alpha: A review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Genetics of suicide in depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Possible association of a polymorphism of the tryptophan hydroxylase gene with suicidal behavior in depressed patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Depressive disorders: toward a unified hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

The biochemistry of affective disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Serotonergic dysfunction in depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Differential diagnosis and pathophysiology of Cushing's syndrome and primary affective disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Direct evidence for an important species difference in the mechanism of 8-OH-DPAT-induced hypothermia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

5-HT1A receptor responsivity in anxiety disorders and depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 September 2017

Functional characterization of the human TPH2 5' regulatory region: untranslated region and polymorphisms modulate gene expression in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

High-sensitive liquid chromatographic method for determination of neuronal release of serotonin, noradrenaline and dopamine monitored by microdialysis in the rat prefrontal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

The effects of selective serotonin reuptake inhibitors on extracellular 5-HT levels in the hippocampus of 5-HT(1B) receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

Serotonergic function and negative and depressive symptomatology in schizophrenia and major depression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

WAY100635-induced augmentation of the 5-HT-elevating action of citalopram: relative importance of the dose of the 5-HT1A (auto)receptor blocker versus that of the 5-HT reuptake inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

Blunted serotonergic responsivity in depressed inpatients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

Aggression, suicide, and serotonin: relationships to CSF amine metabolites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

5-Hydroxytryptamine in the Hind-Brain of Depressive Suicides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

5-hydroxytryptophan for depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). A model of presynaptic 5-HT1 function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

Serotonergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

HPA-Axis hormones and prolactin responses to dextro-fenfluramine in depressed patients and healthy controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

Hormone responses to fenfluramine and placebo challenge in endogenous depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

"Serotonin Depression"—A Biochemical Subgroup Within the Affective Disorders?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

31 May 2018

Understanding the heterogeneity of depression through the triad of symptoms, course and risk factors: a longitudinal, population-based study.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Causal relationship between stressful life events and the onset of major depression

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

The interrelationship of neuroticism, sex, and stressful life events in the prediction of episodes of major depression

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Job insecurity, socio-economic circumstances and depression.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Effects of acute tryptophan depletion on mood and cognitive functioning in older recovered depressed subjects

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Increased expression of the 5-HT transporter confers a low-anxiety phenotype linked to decreased 5-HT transmission.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Aggressivity, suicide attempts, and depression: relationship to cerebrospinal fluid monoamine metabolite levels

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Borderline personality disorder.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Contrasting neuroendocrine responses in depression and chronic fatigue syndrome.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

State and trait abnormalities in serotonin function in major depression

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Prolactin response to D-fenfluramine in outpatients with major depression.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Fenfluramine challenge in unipolar depression with and without anger attacks.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

5-Hydroxytryptamine 1A receptors, major depression, and suicidal behavior

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Higher expression of serotonin 5-HT(2A) receptors in the postmortem brains of teenage suicide victims

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Higher postmortem prefrontal 5-HT2A receptor binding correlates with lifetime aggression in suicide

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Polymorphisms in the neuronal isoform of tryptophan hydroxylase 2 are associated with bipolar disorder in French Canadian pedigrees.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Effect of SNP at position 40237 in exon 7 of the TPH2 gene on susceptibility to suicide.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Tryptophan hydroxylation in brain.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

HYDROXYLATION OF TRYPTOPHAN BY BRAIN TISSUE IN VIVO AND RELATED ASPECTS OF 5-HYDROXYTRYPTAMINE METABOLISM.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Aromatic L-amino acid decarboxylase deficiency: clinical features, drug therapy and follow-up

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Strain-specific genetics, anatomy and function of enteric neural serotonergic pathways in inbred mice.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Analysis of the novel TPH2 gene in bipolar disorder and suicidality

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Lack of association of TPH2 exon XI polymorphisms with major depression and treatment resistance.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

A loss-of-function mutation in tryptophan hydroxylase 2 segregating with attention-deficit/hyperactivity disorder

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

A tryptophan hydroxylase 2 gene polymorphism is associated with panic disorder

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

TPH2 -703G/T SNP may have important effect on susceptibility to suicidal behavior in major depression

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Functional promoter polymorphism of the neuronal isoform of tryptophan hydroxylase (Tph2) in suicide.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Genetic architecture of the human tryptophan hydroxylase 2 Gene: existence of neural isoforms and relevance for major depression

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Tryptophan hydroxylase-2 controls brain serotonin synthesis

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Genotype-dependent activity of tryptophan hydroxylase-2 determines the response to citalopram in a mouse model of depression.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Strain differences in basal and post-citalopram extracellular 5-HT in the mouse medial prefrontal cortex and dorsal hippocampus: relation with tryptophan hydroxylase-2 activity

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Strain-dependent antidepressant-like effects of citalopram in the mouse tail suspension test

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Insensitivity of NMRI mice to selective serotonin reuptake inhibitors in the tail suspension test can be reversed by co-treatment with 5-hydroxytryptophan

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Digging and marble burying in mice: simple methods for in vivo identification of biological impacts.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

An evaluation of the effect of NAS-181, a new selective 5-HT(1B) receptor antagonist, on extracellular 5-HT levels in rat frontal cortex

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Association Between the Tryptophan Hydroxylase Gene and Manic-depressive Illness

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

21 January 2018

Severe and anxious depression: combining definitions of clinical sub-types to identify patients differentially responsive to selective serotonin reuptake inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 November 2018

Elevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 November 2018

Increased 5-HT(2A) receptor binding in euthymic, medication-free patients recovered from depression: a positron emission study with [(11)C]MDL 100,907.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 November 2018

Genetics of recurrent early-onset depression (GenRED): design and preliminary clinical characteristics of a repository sample for genetic linkage studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 November 2018

Control of serotonergic function in medial prefrontal cortex by serotonin-2A receptors through a glutamate-dependent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 November 2018

S33005, a novel ligand at both serotonin and norepinephrine transporters: I. Receptor binding, electrophysiological, and neurochemical profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 November 2018

Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 November 2018

Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit suicide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405680

28 November 2018

Neurotransmitters and suicidal behavior. The evidence from cerebrospinal fluid studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blunted temperature and cortisol responses to ipsapirone in major depression: lack of enhancement by electroconvulsive therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin receptors in suicide victims with major depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolactin response to D-fenfluramine and suicidal behavior in depressed patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma prolactin changes following fenfluramine in depressed patients compared to controls: an evaluation of central serotonergic responsivity in depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1A Receptor Function in Normal Subjects on Clinical Doses of Fluoxetine Blunted Temperature and Hormone Responses to Ipsapirone Challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolactin and cortisol responses to d-fenfluramine in major depression: evidence for diminished responsivity of central serotonergic function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased serotonin-2 binding sites in frontal cortex of suicide victims

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relapse of depression after rapid depletion of tryptophan

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psychiatric phenomena in Alzheimer's disease. III: Disorders of mood

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of tryptophan hydroxylase-2 gene variants on suicide risk in major depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonergic measures in the brains of suicide victims: 5-HT2 binding sites in the frontal cortex of suicide victims and control subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1A receptor sensitivity in major depression. A neuroendocrine study with buspirone

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuroendocrine response to fenfluramine in depressives and normal controls

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amine Precursors and Depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in tissue serotonin following administration of its precursor 5-hydroxytryptophan

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma cortisol, prolactin, growth hormone, and immunoreactive beta-endorphin response to fenfluramine challenge in depressed patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22826344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased 5-HT 2A Receptor Binding in Euthymic, Medication-Free Patients Recovered From Depression: A Positron Emission Study With [ 11 C]MDL 100,907

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2012.0109

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1098/RSTB.2012.0109

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q26849351&oldid=1966599436"