(Q37378691)

20 August 2017

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title

Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders (English)

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20 August 2017

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1

Sophie Erhardt

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20 August 2017

Sara K Olsson

2

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20 August 2017

Göran Engberg

series ordinal

3

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20 August 2017

publication date

1 January 2009

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20 August 2017

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20 August 2017

volume

23

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20 August 2017

issue

2

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20 August 2017

page(s)

91-101

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https://scigraph.springernature.com/pub.10.2165/00023210-200923020-00001

20 August 2017

exact match

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cites work

Organic ion transport during seven decades. The amino acids

1 reference

https://api.crossref.org/works/10.2165%2F00023210-200923020-00001

Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00023210-200923020-00001

Nicotinylalanine increases cerebral kynurenic acid content and has anticonvulsant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00023210-200923020-00001

Kynurenine pathway abnormalities in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00023210-200923020-00001

Recent advances in the phencyclidine model of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00023210-200923020-00001

Dose escalation study of the NMDA glycine-site antagonist licostinel in acute ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00023210-200923020-00001

Dopamine in schizophrenia: a review and reconceptualization

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00023210-200923020-00001

Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum

21 January 2018

1 reference

12 December 2020

Excitation of nigral dopamine neurons by the GABA(A) receptor agonist muscimol is mediated via release of glutamate

1 reference

12 December 2020

The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications

1 reference

12 December 2020

Activation of rat ventral tegmental area dopamine neurons by endogenous kynurenic acid: a pharmacological analysis

1 reference

12 December 2020

Modulators of the Kynurenine Pathway of Tryptophan Metabolism: Synthesis and Preliminary Biological Evaluation of (S)-4-(Ethylsulfonyl)benzoylalanine, a Potent and Selective Kynurenine Aminotransferase II (KAT II) Inhibitor

1 reference

12 December 2020

Activation of noradrenergic locus coeruleus neurons by clozapine and haloperidol: involvement of glutamatergic mechanisms

1 reference

12 December 2020

A role of excitatory amino acids in the activation of locus coeruleus neurons following cutaneous thermal stimuli.

1 reference

12 December 2020

Effects of COX-1 and COX-2 inhibitors on the firing of rat midbrain dopaminergic neurons--possible involvement of endogenous kynurenic acid

1 reference

12 December 2020

Increased cortical kynurenate content in schizophrenia

1 reference

12 December 2020

Glycine site associated with the NMDA receptor modulates long-term potentiation

1 reference

12 December 2020

Kynurenic acid has a dual action on AMPA receptor responses.

1 reference

12 December 2020

Cerebrospinal fluid levels of kynurenine pathway metabolites in patients with eating disorders: relation to clinical and biochemical variable

1 reference

12 December 2020

The conversion of tryptophan to kynurenine in liver. II. The enzymatic hydrolysis of formylkynurenine.

1 reference

12 December 2020

Kynurenic acid blocks nicotinic synaptic transmission to hippocampal interneurons in young rats.

1 reference

12 December 2020

Kynurenergic manipulations influence excitatory synaptic function and excitotoxic vulnerability in the rat hippocampus in vivo

1 reference

12 December 2020

Regulation of spontaneous activity and oscillatory spike firing in rat midbrain dopamine neurons recorded in vitro

1 reference

12 December 2020

Cerebrospinal fluid kynurenic acid in male patients with schizophrenia – correlation with monoamine metabolites

1 reference

12 December 2020

Nicotinylalanine increases the formation of kynurenic acid in the brain and antagonizes convulsions.

1 reference

12 December 2020

An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid.

1 reference

12 December 2020

Nicotinic acetylcholine involvement in cognitive function in animals

1 reference

12 December 2020

Pharmacologically elevated levels of endogenous kynurenic acid prevent nicotine-induced activation of nigral dopamine neurons

1 reference

12 December 2020

A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists

1 reference

12 December 2020

Kynurenine metabolism in Alzheimer's disease.

1 reference

12 December 2020

Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease

1 reference

12 December 2020

Viruses and schizophrenia, connection or coincidence?

1 reference

12 December 2020

MK-801, phencyclidine (PCP), and PCP-like drugs increase burst firing in rat A10 dopamine neurons: comparison to competitive NMDA antagonists.

1 reference

12 December 2020

Kynurenic acid and schizophrenia

1 reference

12 December 2020

Kynurenines in the CNS: from endogenous obscurity to therapeutic importance

1 reference

12 December 2020

Kynurenic acid: a potential pathogen in brain disorders.

1 reference

12 December 2020

Glial fibrillary acidic protein-immunoreactive astrocytosis in elderly patients with schizophrenia and dementia

1 reference

12 December 2020

Prostaglandin-mediated control of rat brain kynurenic acid synthesis--opposite actions by COX-1 and COX-2 isoforms

1 reference

12 December 2020

Maternal infections and subsequent psychosis among offspring.

1 reference

12 December 2020

Blood?Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism

1 reference

12 December 2020

Differential contribution of NMDA receptors in hippocampal subregions to spatial working memory

1 reference

12 December 2020

Characterization of kynurenine aminotransferase III, a novel member of a phylogenetically conserved KAT family.

1 reference

12 December 2020

S100B serum levels and long-term improvement of negative symptoms in patients with schizophrenia

1 reference

12 December 2020

Measurement of kynurenic acid in mammalian brain extracts and cerebrospinal fluid by high-performance liquid chromatography with fluorometric and coulometric electrode array detection

1 reference

12 December 2020

A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia

1 reference

12 December 2020

Hippocampal synaptic plasticity and NMDA receptors: a role in information storage?

1 reference

12 December 2020

Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring.

1 reference

12 December 2020

Kynurenic acid blocks chemogenic nociception

1 reference

12 December 2020

Acute psychotic symptoms in HIV-1 infected patients are associated with increased levels of kynurenic acid in cerebrospinal fluid.

1 reference

12 December 2020

Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia

1 reference

12 December 2020

Characterization of human brain kynurenine aminotransferases using [3H]kynurenine as a substrate.

1 reference

12 December 2020

Subchronic treatment with kynurenine and probenecid: effects on prepulse inhibition and firing of midbrain dopamine neurons

1 reference

12 December 2020

1 reference

12 December 2020

No evidence for astrogliosis in brains of schizophrenic patients. A post-mortem study.

1 reference

12 December 2020

The conversion of kynurenic acid to quinaldic acid by humans and rats

1 reference

12 December 2020

Modulation of extracellular kynurenic acid content by excitatory amino acids in primary cultures of rat astrocytes

1 reference

12 December 2020

Working memory deficit as a core neuropsychological dysfunction in schizophrenia.

1 reference

12 December 2020

Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities

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12 December 2020

Acute and chronic changes in kynurenate formation following an intrastriatal quinolinate injection in rats.

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12 December 2020

New roles for astrocytes: Regulation of synaptic transmission

1 reference

12 December 2020

Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission

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12 December 2020

Brain-specific modulation of kynurenic acid synthesis in the rat.

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12 December 2020

The role of cerebellar genes in pathology of autism and schizophrenia

1 reference

12 December 2020

Inhibition of system A-mediated glycine transport in cortical synaptosomes by therapeutic concentrations of clozapine: implications for mechanisms of action

1 reference

12 December 2020

Gene expression changes in brains of mice exposed to a maternal virus infection

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12 December 2020

Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome

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12 December 2020

Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain

1 reference

12 December 2020

Phencyclidine and the midbrain dopamine system: electrophysiology and behavior

1 reference

12 December 2020

Neuropharmacology of quinolinic and kynurenic acids

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12 December 2020

Clozapine modulates midbrain dopamine neuron firing via interaction with the NMDA receptor complex

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12 December 2020

Induction of the kynurenine pathway by neurotropic influenza A virus infection

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12 December 2020

Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

1 reference

12 December 2020

The effect of hormones and vitamin B6 on urinary excretion of metabolites of the kynurenine pathway

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12 December 2020

Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex

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12 December 2020

L-alpha-aminoadipate inhibits kynurenate synthesis in rat brain hippocampus and tissue culture.

1 reference

12 December 2020

Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid

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12 December 2020

On the disposition of intrahippocampally injected kynurenic acid in the rat.

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12 December 2020

Dopamine as the wind of the psychotic fire: new evidence from brain imaging studies

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12 December 2020

Intrahippocampal administration of a glycine site antagonist impairs working memory performance of rats.

1 reference

12 December 2020

Strain-specific nicotinic modulation of glutamatergic transmission in the CA1 field of the rat hippocampus: August Copenhagen Irish versus Sprague-Dawley.

1 reference

12 December 2020

Is there gliosis in schizophrenia? Investigation of the temporal lobe.

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12 December 2020

Studies on cerebrospinal fluid kynurenic acid concentrations in epileptic children

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12 December 2020

Gliosis in schizophrenia: a survey

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12 December 2020

Glutamate and kynurenate in the rat central nervous system following treatments with tail ischaemia or diclofenac.

1 reference

12 December 2020

The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia

1 reference

12 December 2020

Beneficial antipsychotic effects of celecoxib add-on therapy compared to risperidone alone in schizophrenia

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12 December 2020

High-affinity uptake of L-kynurenine by a Na+-independent transporter of neutral amino acids in astrocytes

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12 December 2020

Measurement of rat brain kynurenine aminotransferase at physiological kynurenine concentrations.

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12 December 2020

Inhibitory action of clozapine on rat ventral tegmental area dopamine neurons following increased levels of endogenous kynurenic acid

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12 December 2020

Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence

1 reference

12 December 2020

Micromolar Brain Levels of Kynurenic Acid are Associated with a Disruption of Auditory Sensory Gating in the Rat

1 reference

12 December 2020

(R,S)-3,4-dichlorobenzoylalanine (FCE 28833A) causes a large and persistent increase in brain kynurenic acid levels in rats.

1 reference

12 December 2020

Cerebrospinal fluid kynurenic acid in male and female controls - correlation with monoamine metabolites and influences of confounding factors

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12 December 2020

Kynurenate production by cultured human astrocytes

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12 December 2020

Two kynurenine aminotransferases in human brain

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12 December 2020

Kynurenine as an Intermediate in the Formation of Nicotinic Acid from Tryptophane by Neurospora

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12 December 2020

Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

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12 December 2020

Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF.

1 reference

12 December 2020

Determination of extracellular kynurenic acid in the striatum of unanesthetized rats: effect of aminooxyacetic acid.

1 reference

12 December 2020

Identification and quantification of kynurenic acid in human brain tissue.

1 reference

12 December 2020

Elevated levels of kynurenic acid change the dopaminergic response to amphetamine: implications for schizophrenia

1 reference

12 December 2020

Toxoplasma gondii as a risk factor for early-onset schizophrenia: analysis of filter paper blood samples obtained at birth

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12 December 2020

Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites

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12 December 2020

The kynurenic acid hypothesis of schizophrenia

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12 December 2020

Elevations of endogenous kynurenic acid produce spatial working memory deficits

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12 December 2020

Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors.

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12 December 2020

Characterization of rat brain kynurenine aminotransferases I and II.

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12 December 2020

Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia

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12 December 2020

Presence of Kynurenic Acid in the Mammalian Brain

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12 December 2020

Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia

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12 December 2020

Nicotine-induced excitation of locus coeruleus neurons is blocked by elevated levels of endogenous kynurenic acid

1 reference

12 December 2020

Absence of neurodegeneration and neural injury in the cerebral cortex in a sample of elderly patients with schizophrenia.

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12 December 2020

Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons

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12 December 2020

Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization

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12 December 2020

Endogenous kynurenic acid disrupts prepulse inhibition

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12 December 2020

Kynurenic acid is present in the rat brain and its content increases during development and aging processes

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12 December 2020

Clozapine interacts with the glycine site of the NMDA receptor: electrophysiological studies of dopamine neurons in the rat ventral tegmental area

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12 December 2020

Psychotropic effects of COX-2 inhibitors--a possible new approach for the treatment of psychiatric disorders

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12 December 2020

Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid

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12 December 2020

Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies

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12 December 2020

Mind glue: implications of glial cell biology for psychiatry

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12 December 2020

Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine.

1 reference

12 December 2020

The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia

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12 December 2020

Serologic evidence of prenatal influenza in the etiology of schizophrenia

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12 December 2020

Endogenous protectant kynurenic acid in amyotrophic lateral sclerosis

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12 December 2020

Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus.

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12 December 2020

Localization of kynurenine aminotransferase immunoreactivity in the rat hippocampus

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12 December 2020

10.2165/00023210-200923020-00001

Identifiers

DOI

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Dimensions Publication ID

20 August 2017

1017091829

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