(Q30531298)

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Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice (English)

1 reference

Europe PubMed Central

14 August 2017

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object named as

M G Caron

1 reference

Europe PubMed Central

14 August 2017

author name string

J P R Jacobsen

1

1 reference

Europe PubMed Central

14 August 2017

W B Siesser

2

1 reference

Europe PubMed Central

14 August 2017

B D Sachs

3

1 reference

Europe PubMed Central

14 August 2017

S Peterson

4

1 reference

Europe PubMed Central

14 August 2017

M J Cools

5

1 reference

Europe PubMed Central

14 August 2017

V Setola

6

1 reference

Europe PubMed Central

14 August 2017

J H A Folgering

7

1 reference

Europe PubMed Central

14 August 2017

G Flik

8

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Europe PubMed Central

14 August 2017

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publication date

3 May 2011

1 reference

Europe PubMed Central

14 August 2017

Molecular Psychiatry

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Europe PubMed Central

14 August 2017

17

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Europe PubMed Central

14 August 2017

7

1 reference

Europe PubMed Central

14 August 2017

694-704

1 reference

Europe PubMed Central

14 August 2017

Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

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Acute and repeated flibanserin administration in female rats modulates monoamines differentially across brain areas: a microdialysis study

1 reference

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5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants

1 reference

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20 June 2018

Structural brain abnormalities in major depressive disorder: a selective review of recent MRI studies

1 reference

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20 June 2018

Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders

1 reference

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20 June 2018

Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter.

1 reference

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20 June 2018

Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants

1 reference

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20 June 2018

Prolactin and dopamine: what is the connection? A review article

1 reference

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20 June 2018

Tph2 gene variants modulate response control processes in adult ADHD patients and healthy individuals.

1 reference

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20 June 2018

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency

1 reference

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20 June 2018

Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

5-HT receptor regulation of neurotransmitter release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Important messages in the 'post': recent discoveries in 5-HT neurone feedback control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Serotonin-1A receptor imaging in recurrent depression: replication and literature review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5'-region are associated with bipolar affective disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Potential mechanisms of action of atypical antipsychotic medications in treatment-resistant depression and anxiety.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Serotonin and depression: a disconnect between the advertisements and the scientific literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

From galactorrhea to osteopenia: rethinking serotonin-prolactin interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Monoamine oxidase and head-twitch response in mice. Mechanisms of alpha-methylated substrate derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Stress-induced hyperthermia and anxiety: pharmacological validation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Do animal models of anxiety predict anxiolytic-like effects of antidepressants?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Crosstalk between the norepinephrine and serotonin systems and its role in the antidepressant response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Regulation of 5-HT(1A) receptor-stimulated [35S]-GtpgammaS binding as measured by quantitative autoradiography following chronic agonist administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Psychopharmacology of 5-HT(1A) receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

PET imaging of serotonin 1A receptor binding in depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA level

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

https://api.crossref.org/works/10.1038%2FMP.2011.50

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential effects of serotonin (5-HT) lesions and synthesis blockade on neuropeptide-Y immunoreactivity and 5-HT1A, 5-HT1B/1D and 5-HT2A/2C receptor binding sites in the rat cerebral cortex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Extracellular dopamine, norepinephrine, and serotonin in the ventral tegmental area and nucleus accumbens of freely moving rats during intracerebral dialysis following systemic administration of cocaine and other uptake blockers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

WAY100635-induced augmentation of the 5-HT-elevating action of citalopram: relative importance of the dose of the 5-HT1A (auto)receptor blocker versus that of the 5-HT reuptake inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

The 5-HT1A antagonist WAY-100635 selectively potentiates the presynaptic effects of serotonergic antidepressants in rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Attempted suicide characteristics and cerebrospinal fluid amine metabolites in depressed inpatients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Rapid agonist-induced internalization of the 5-hydroxytryptamine2A receptor occurs via the endosome pathway in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Blunted serotonergic responsivity in depressed inpatients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Aggression, suicide, and serotonin: relationships to CSF amine metabolites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

5-Hydroxytryptamine in the Hind-Brain of Depressive Suicides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

The biochemistry of affective disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Serotonergic dysfunction in depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

5-HT1A receptor responsivity in anxiety disorders and depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

20 June 2018

Tryptophan depletion during continuous CSF sampling in healthy human subjects.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Higher expression of serotonin 5-HT(2A) receptors in the postmortem brains of teenage suicide victims

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Effects of imipramine on extracellular serotonin and noradrenaline concentrations in ACTH-treated rats.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Effect of chronic tryptophan depletion on the circadian rhythm of wheel-running activity in rats.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Serotonin-1A receptor function in the dorsal raphe nucleus following chronic administration of the selective serotonin reuptake inhibitor sertraline

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Insensitivity of NMRI mice to selective serotonin reuptake inhibitors in the tail suspension test can be reversed by co-treatment with 5-hydroxytryptophan

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Relationship between brain serotonin transporter binding, plasma concentration and behavioural effect of selective serotonin reuptake inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Neurochemical responses to antidepressants in the prefrontal cortex of mice and their efficacy in preclinical models of anxiety-like and depression-like behavior: a comparative and correlational study

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Tryptophan hydroxylase 2 gene is associated with major depression and antidepressant treatment response

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Association of brain-specific tryptophan hydroxylase, TPH2, with unipolar and bipolar disorder in a Northern Swedish, isolated population.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Changes of body temperature and extracellular serotonin level in the preoptic area and anterior hypothalamus after thermal or serotonergic pharmacological stimulation of freely moving rats

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Acute treatment with the antidepressant fluoxetine internalizes 5-HT1A autoreceptors and reduces the in vivo binding of the PET radioligand [18F]MPPF in the nucleus raphe dorsalis of rat.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Pharmacology of Antidepressants

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.50

21 January 2018

Increased 5-HT(2A) receptor binding in euthymic, medication-free patients recovered from depression: a positron emission study with [(11)C]MDL 100,907.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

26 November 2018

Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

26 November 2018

Long-term antidepressant treatments result in a tonic activation of forebrain 5-HT1A receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

26 November 2018

Changes in extracellular serotonin in rat hypothalamus affect thermoregulatory function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536482

26 November 2018

AAPS-FDA Workshop White Paper: microdialysis principles, application, and regulatory perspectives

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolactin response to D-fenfluramine and suicidal behavior in depressed patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blunted temperature and cortisol responses to ipsapirone in major depression: lack of enhancement by electroconvulsive therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A physiological method to selectively decrease brain serotonin release

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobiology of suicidal behaviour

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased serotonin-2 binding sites in frontal cortex of suicide victims

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete amino acid sequence of mouse prolactin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of local application of 5-HT and 8-OH-DPAT into the dorsal and median raphe nuclei on core temperature in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1A receptor sensitivity in major depression. A neuroendocrine study with buspirone

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-(2'-Methoxy-phenyl)-1-[2'-(n-2"-pyridinyl)-p-iodobenzamido]-ethyl- piperazine ([125I]p-MPPI) as a new selective radioligand of serotonin-1A sites in rat brain: in vitro binding and autoradiographic studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotransmitters and suicidal behavior. The evidence from cerebrospinal fluid studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute tryptophan depletion attenuates the prolactin response to d-fenfluramine challenge in healthy human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1A Receptor Function in Normal Subjects on Clinical Doses of Fluoxetine Blunted Temperature and Hormone Responses to Ipsapirone Challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/21537332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MP.2011.50

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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