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The role of H2S bioavailability in endothelial dysfunction
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scholarly article
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PubMed
review article
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Europe PubMed Central
title
The role of H2S bioavailability in endothelial dysfunction
(English)
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PubMed
main subject
endothelium
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bioavailability
1 reference
based on heuristic
inferred from title
author
Matthew Whiteman
series ordinal
5
object named as
Matthew Whiteman
1 reference
stated in
Crossref
author name string
Rui Wang
series ordinal
1
1 reference
stated in
Crossref
Csaba Szabo
series ordinal
2
1 reference
stated in
Crossref
Fumito Ichinose
series ordinal
3
1 reference
stated in
Crossref
Asif Ahmed
series ordinal
4
1 reference
stated in
Crossref
Andreas Papapetropoulos
series ordinal
6
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stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
September 2015
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stated in
PubMed
published in
Trends in Pharmacological Sciences
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stated in
PubMed
volume
36
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stated in
PubMed
issue
9
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stated in
PubMed
page(s)
568-78
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stated in
PubMed
cites work
Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation
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PubMed Central
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7 April 2017
H2S during circulatory shock: some unresolved questions
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PubMed Central
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7 April 2017
Hydrogen sulfide inhibits the development of atherosclerosis with suppressing CX3CR1 and CX3CL1 expression
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7 April 2017
Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation
1 reference
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PubMed Central
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7 April 2017
Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs
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PubMed Central
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7 April 2017
H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase
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PubMed Central
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7 April 2017
The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener
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7 April 2017
Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter
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28 September 2017
Regulation of Vascular Tone, Angiogenesis and Cellular Bioenergetics by the 3-Mercaptopyruvate Sulfurtransferase/H2S Pathway: Functional Impairment by Hyperglycemia and Restoration by DL-α-Lipoic Acid.
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28 September 2017
Role of hydrogen sulfide in early blood-brain barrier disruption following transient focal cerebral ischemia.
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28 September 2017
High glucose induces the release of endothelin-1 through the inhibition of hydrogen sulfide production in HUVECs
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28 September 2017
Molecular mechanisms of maternal vascular dysfunction in preeclampsia
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28 September 2017
Unravelling the theories of pre-eclampsia: are the protective pathways the new paradigm?
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28 September 2017
Sodium thiosulfate attenuates acute lung injury in mice
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28 September 2017
Emerging role of hydrogen sulfide in hypertension and related cardiovascular diseases
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PubMed Central
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28 September 2017
H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway
1 reference
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PubMed Central
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28 September 2017
Hydrogen sulfide and endothelial dysfunction: relationship with nitric oxide.
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28 September 2017
Shear stress-initiated signaling and its regulation of endothelial function
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28 September 2017
Arterial baroreflex dysfunction impairs ischemia-induced angiogenesis
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28 September 2017
AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro
1 reference
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PubMed Central
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28 September 2017
Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent
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PubMed Central
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28 September 2017
Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition.
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PubMed Central
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28 September 2017
Role of the M3 muscarinic acetylcholine receptor subtype in murine ophthalmic arteries after endothelial removal
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28 September 2017
Hydrogen sulfide attenuates sFlt1-induced hypertension and renal damage by upregulating vascular endothelial growth factor
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PubMed Central
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28 September 2017
Effect of type 1 diabetes on the production and vasoactivity of hydrogen sulfide in rat middle cerebral arteries
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28 September 2017
Cystathionine γ-lyase deficiency protects mice from galactosamine/lipopolysaccharide-induced acute liver failure
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28 September 2017
The hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E(-/-) mice
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28 September 2017
Cystathionine γ-lyase protects against renal ischemia/reperfusion by modulating oxidative stress
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PubMed Central
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28 September 2017
Reduced cystathionine γ-lyase and increased miR-21 expression are associated with increased vascular resistance in growth-restricted pregnancies: hydrogen sulfide as a placental vasodilator.
1 reference
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PubMed Central
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28 September 2017
Hydrogen sulfide protects HUVECs against hydrogen peroxide induced mitochondrial dysfunction and oxidative stress
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
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28 September 2017
H₂S protects against pressure overload-induced heart failure via upregulation of endothelial nitric oxide synthase
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
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28 September 2017
cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation.
1 reference
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PubMed Central
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28 September 2017
VEGFR2 functions as an H2S-targeting receptor protein kinase with its novel Cys1045-Cys1024 disulfide bond serving as a specific molecular switch for hydrogen sulfide actions in vascular endothelial cells
1 reference
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PubMed Central
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28 September 2017
Hydrogen sulfide modulates the release of nitric oxide and VEGF in human keratinocytes
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PubMed Central
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28 September 2017
Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols
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28 September 2017
Shared signaling pathways among gasotransmitters
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28 September 2017
Physiological implications of hydrogen sulfide: a whiff exploration that blossomed
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28 September 2017
Genetics of ischemic stroke, stroke-related risk factors, stroke precursors and treatments
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28 September 2017
Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production
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28 September 2017
Inhaled hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice.
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28 September 2017
Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels
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28 September 2017
Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function
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28 September 2017
Induction of heme oxygenase 1 attenuates placental ischemia-induced hypertension
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28 September 2017
Measurement of plasma hydrogen sulfide in vivo and in vitro
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28 September 2017
Antecedent hydrogen sulfide elicits an anti-inflammatory phenotype in postischemic murine small intestine: role of BK channels
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28 September 2017
Endothelium-derived hyperpolarising factors and associated pathways: a synopsis
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28 September 2017
Low levels of hydrogen sulfide in the blood of diabetes patients and streptozotocin-treated rats causes vascular inflammation?
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28 September 2017
Hydrogen sulfide is an endogenous stimulator of angiogenesis.
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28 September 2017
The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages
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28 September 2017
Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide.
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28 September 2017
Hydrogen sulfide: a new EDRF.
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28 September 2017
Endothelial Ca+-activated K+ channels in normal and impaired EDHF-dilator responses--relevance to cardiovascular pathologies and drug discovery
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28 September 2017
Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction
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28 September 2017
The endogenous production of hydrogen sulphide in intrauterine tissues
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28 September 2017
Supression of hemin-mediated oxidation of low-density lipoprotein and subsequent endothelial reactions by hydrogen sulfide (H(2)S).
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28 September 2017
H2S-donating sildenafil (ACS6) inhibits superoxide formation and gp91phox expression in arterial endothelial cells: role of protein kinases A and G
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28 September 2017
Biosynthesis of H2S is impaired in non-obese diabetic (NOD) mice.
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28 September 2017
Effects of hydrogen sulfide on homocysteine-induced oxidative stress in vascular smooth muscle cells
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28 September 2017
Hydrogen sulfide-induced relaxation of resistance mesenteric artery beds of rats
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28 September 2017
Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter?
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28 September 2017
Long term mortality of mothers and fathers after pre-eclampsia: population based cohort study
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28 September 2017
Leptin-induced endothelium-dependent vasorelaxation of peripheral arteries in lean and obese rats: role of nitric oxide and hydrogen sulfide
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31 May 2018
H(2)S inhibits oscillatory shear stress-induced monocyte binding to endothelial cells via nitric oxide production
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31 May 2018
Endothelial cell peroxisome proliferator-activated receptor γ reduces endotoxemic pulmonary inflammation and injury.
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31 May 2018
Effects of AP39, a novel triphenylphosphonium derivatised anethole dithiolethione hydrogen sulfide donor, on rat haemodynamic parameters and chloride and calcium Cav3 and RyR2 channels.
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28 November 2018
Hydrogen sulfide is involved in dexamethasone-induced hypertension in rat
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28 November 2018
The coordination of S-sulfhydration, S-nitrosylation, and phosphorylation of endothelial nitric oxide synthase by hydrogen sulfide
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28 November 2018
Maternal morbidity associated with early-onset and late-onset preeclampsia.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
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28 November 2018
Hydrogen sulfide increases nitric oxide production and subsequent S-nitrosylation in endothelial cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
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28 November 2018
Hydrogen sulfide treatment induces angiogenesis after cerebral ischemia.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
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28 November 2018
Hydrogen sulfide protects blood-brain barrier integrity following cerebral ischemia.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
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28 November 2018
Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis
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PubMed Central
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28 November 2018
Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
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28 November 2018
Hydrogen sulfide suppresses high glucose-induced expression of intercellular adhesion molecule-1 in endothelial cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
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28 November 2018
Hydrogen sulfide prevents H₂O₂-induced senescence in human umbilical vein endothelial cells through SIRT1 activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
H₂S is an endothelium-derived hyperpolarizing factor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Hydrogen sulfide promotes nitric oxide production in corpus cavernosum by enhancing expression of endothelial nitric oxide synthase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Hydrogen sulfide increases nitric oxide production with calcium-dependent activation of endothelial nitric oxide synthase in endothelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Hydrogen sulfide is an endogenous inhibitor of phosphodiesterase activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
NaHS ameliorates diabetic vascular injury by correcting depressed connexin 43 and 40 in the vasculature in streptozotocin-injected rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
A monobromobimane-based assay to measure the pharmacokinetic profile of reactive sulphide species in blood
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Adiposity is a major determinant of plasma levels of the novel vasodilator hydrogen sulphide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Hydrogen sulfide induces nitric oxide release from nitrite
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Role of hydrogen sulfide in the development of atherosclerotic lesions in apolipoprotein E knockout mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Plasma hydrogen sulfide and homocysteine levels in hypertensive patients with different blood pressure levels and complications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Negative regulation of soluble Flt-1 and soluble endoglin release by heme oxygenase-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
The possible role of hydrogen sulfide on the pathogenesis of spontaneous hypertension in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4562801
retrieved
28 November 2018
Hydrogen sulfide impairs shear stress-induced vasodilation in mouse coronary arteries
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The vasorelaxant effect of hydrogen sulfide is enhanced in streptozotocin-induced diabetic rats
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Connexins and M3 muscarinic receptors contribute to heterogeneous Ca(2+) signaling in mouse aortic endothelium
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inhibitory effect of hydrogen sulfide on platelet aggregation and the underlying mechanisms
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines via NF-kappaB
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The anti-thrombotic effect of hydrogen sulfide is partly mediated by an upregulation of nitric oxide synthases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hydrogen sulfide downregulates the aortic L-arginine/nitric oxide pathway in rats
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Down-regulated CBS/H2S pathway is involved in high-salt-induced hypertension in Dahl rats
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hydrogen sulfide treatment reduces blood pressure and oxidative stress in angiotensin II-induced hypertensive mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hydrogen sulfide protects against high-glucose-induced apoptosis in endothelial cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26071118
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effects of insulin on CYP3A activity and nicardipine disposition in streptozotocin-induced diabetic rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.TIPS.2015.05.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/J.TIPS.2015.05.007
0 references
PMCID
4562801
1 reference
stated in
PubMed
PubMed ID
26071118
1 reference
stated in
PubMed
ResearchGate publication ID
278050018
0 references
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