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K11-linked ubiquitin chains as novel regulators of cell division
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title
K11-linked ubiquitin chains as novel regulators of cell division
(English)
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PubMed
author name string
Katherine E. Wickliffe
series ordinal
1
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Crossref
Adam Williamson
series ordinal
2
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Crossref
Hermann-Josef Meyer
series ordinal
3
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Crossref
Aileen Kelly
series ordinal
4
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Michael Rape
series ordinal
5
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language of work or name
English
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PubMed
publication date
November 2011
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stated in
PubMed
published in
Trends in Cell Biology
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stated in
PubMed
volume
21
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PubMed
page(s)
656-63
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PubMed
issue
11
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PubMed
cites work
Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry
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Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage
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Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne
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Active site remodelling accompanies thioester bond formation in the SUMO E1
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Identification of a physiological E2 module for the human anaphase-promoting complex
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UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit
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Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation
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The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction
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UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover
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Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex
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Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities
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UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation
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Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C
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APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex
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Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase
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7 April 2017
An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme
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Modulation of K11-linkage formation by variable loop residues within UbcH5A
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7 April 2017
K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody
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Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex
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Structural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10
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Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail
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RING domain E3 ubiquitin ligases
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A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis
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Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism.
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7 April 2017
Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone
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7 April 2017
Cyclin is degraded by the ubiquitin pathway
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Breaking the chains: structure and function of the deubiquitinases
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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
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7 April 2017
A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation
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Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia
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7 April 2017
Essential role for ubiquitin-ubiquitin-conjugating enzyme interaction in ubiquitin discharge from Cdc34 to substrate
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7 April 2017
A proteomics approach to understanding protein ubiquitination
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7 April 2017
A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein
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7 April 2017
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
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7 April 2017
Building ubiquitin chains: E2 enzymes at work
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7 April 2017
Physiological functions of the HECT family of ubiquitin ligases
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7 April 2017
Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex
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7 April 2017
Identification of genes periodically expressed in the human cell cycle and their expression in tumors
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7 April 2017
Protein standard absolute quantification (PSAQ) method for the measurement of cellular ubiquitin pools
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28 September 2017
Cohesion fatigue induces chromatid separation in cells delayed at metaphase
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28 September 2017
Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease
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28 September 2017
c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling
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28 September 2017
Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.
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28 September 2017
Post-translational modifications in signal integration
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28 September 2017
Regulated degradation of spindle assembly factors by the anaphase-promoting complex.
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28 September 2017
ATP is required for the release of the anaphase-promoting complex/cyclosome from inhibition by the mitotic checkpoint
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28 September 2017
UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex
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PubMed Central
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28 September 2017
Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation
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28 September 2017
The family of ubiquitin-conjugating enzymes (E2s): deciding between life and death of proteins
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28 September 2017
Linear polyubiquitination: a new regulator of NF-kappaB activation.
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28 September 2017
Cdc20 and Cks direct the spindle checkpoint-independent destruction of cyclin A.
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28 September 2017
E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis
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28 September 2017
NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules
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28 September 2017
Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.
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28 September 2017
Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin
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28 September 2017
Cell cycle-dependent expression of mammalian E2-C regulated by the anaphase-promoting complex/cyclosome
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28 September 2017
Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates
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28 September 2017
Regulation of ubiquitin chain initiation to control the timing of substrate degradation.
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31 May 2018
Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor
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31 May 2018
Efficient internalization of MHC I requires lysine-11 and lysine-63 mixed linkage polyubiquitin chains.
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31 May 2018
Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.
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31 May 2018
The ubiquitin-conjugating enzyme E2-EPF is overexpressed in primary breast cancer and modulates sensitivity to topoisomerase II inhibition
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31 May 2018
Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205209
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31 May 2018
UbcH10 expression may be a useful tool in the prognosis of ovarian carcinomas
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PubMed Central
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31 May 2018
Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
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31 May 2018
Detection of sequential polyubiquitylation on a millisecond timescale
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28 November 2018
Clinicopathological relevance of UbcH10 in breast cancer.
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28 November 2018
The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC.
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28 November 2018
UbcH10 has a rate-limiting role in G1 phase but might not act in the spindle checkpoint or as part of an autonomous oscillator.
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28 November 2018
NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling.
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HURP Is a Ran-Importin β-Regulated Protein that Stabilizes Kinetochore Microtubules in the Vicinity of Chromosomes
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Identifiers
DOI
10.1016/J.TCB.2011.08.008
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1925823
OpenCitations bibliographic resource ID
1925823
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1925823
PMCID
3205209
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1925823
PubMed ID
21978762
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1925823
ResearchGate publication ID
51698866
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