(Q45305824)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Global changes to the ubiquitin system in Huntington's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

0 references

7

1 reference

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3 January 2020

Kwon-Yul Ryu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

Eric J Bennett

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Thomas A Shaler

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Ben Woodman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Tatiana S Zaitseva

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Christopher H Becker

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Howard Schulman

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Ron R Kopito

9

1 reference

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3 January 2020

language of work or name

English

0 references

publication date

1 August 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

volume

448

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

issue

7154

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

page(s)

704-708

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

3 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Huntington's disease: the challenge for cell biologists

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodie

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

The ubiquitin-proteasome pathway in Parkinson's disease and other neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Polyubiquitin chains: polymeric protein signals

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Impairment of the ubiquitin-proteasome system by protein aggregation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Aggregate formation inhibits proteasomal degradation of polyglutamine proteins.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Polyglutamine-expanded ataxin-7 decreases nuclear translocation of NF-kappaB p65 and impairs NF-kappaB activity by inhibiting proteasome activity of cerebellar neurons

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Diverse polyubiquitin interaction properties of ubiquitin-associated domains

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Characterization of beta-endorphin in human pituitary by fast atom bombardment mass spectrometry of trypsin-generated fragments

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Using deubiquitylating enzymes as research tools

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

A transgenic mouse model of the ubiquitin/proteasome system

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Neurological abnormalities in a knock-in mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Ubiquitin-specific protease 2 as a tool for quantification of total ubiquitin levels in biological specimens

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06022

7 January 2021

Identifiers

DOI

10.1038/NATURE06022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17687326%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 January 2020

1024911462

0 references

Fatcat ID

release_5mc2ykjlynhd5h2kuwg5ftpl7y

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5mc2ykjlynhd5h2kuwg5ftpl7y

24 November 2022

mapped directly with Wikidata item

1 reference