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DNA DSB repair pathway choice: an orchestrated handover mechanism
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scholarly article
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PubMed
title
DNA DSB repair pathway choice: an orchestrated handover mechanism
(English)
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stated in
PubMed
author name string
A Kakarougkas
series ordinal
1
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Crossref
P A Jeggo
series ordinal
2
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
March 2014
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PubMed
published in
British Journal of Radiology
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stated in
PubMed
volume
87
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PubMed
issue
1035
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PubMed
page(s)
20130685
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PubMed
cites work
53BP1: pro choice in DNA repair
1 reference
stated in
PubMed Central
reference URL
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21 March 2017
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
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PubMed Central
reference URL
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21 March 2017
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
1 reference
stated in
PubMed Central
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21 March 2017
Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
Insights into DNA recombination from the structure of a RAD51-BRCA2 complex
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
Instability and decay of the primary structure of DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
Factors determining DNA double-strand break repair pathway choice in G2 phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
DNA Repair Enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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21 March 2017
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
7 April 2017
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
7 April 2017
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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7 April 2017
Double-strand break end resection and repair pathway choice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
7 April 2017
Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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7 April 2017
Brca1 controls homology-directed DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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7 April 2017
Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
Opposing roles for 53BP1 during homologous recombination.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
28 September 2017
A noncatalytic function of the ligation complex during nonhomologous end joining
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
28 September 2017
The heterochromatic barrier to DNA double strand break repair: how to get the entry visa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
28 September 2017
GADD45α inhibition of DNMT1 dependent DNA methylation during homology directed DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
28 September 2017
Choosing the right path: does DNA-PK help make the decision?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
28 September 2017
The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
28 September 2017
Inhibition of homologous recombination by DNA-dependent protein kinase requires kinase activity, is titratable, and is modulated by autophosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
28 September 2017
The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
Assembly and function of DNA double-strand break repair foci in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
Pathways of mammalian replication fork restart.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
Collaboration and competition between DNA double-strand break repair pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
retrieved
28 September 2017
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
Regulatory ubiquitylation in response to DNA double-strand breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
Somatic Cells Efficiently Join Unrelated DNA Segments End-to-End
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae
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PubMed Central
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28 September 2017
Studies on mammalian mutants defective in rejoining double-strand breaks in DNA.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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28 September 2017
KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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31 May 2018
Out of the shadows and into the light: the emergence of DNA repair.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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31 May 2018
Genetic analysis of the recF pathway to genetic recombination in Escherichia coli k12: Isolation and characterization of mutants
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064598
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31 May 2018
The recombination and integration of DNAs introduced into mouse L cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24363387
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Quantitation of the involvement of the recA, recB, recC, recF, recJ, recN, lexA, radA, radB, uvrD, and umuC genes in the repair of X-ray-induced DNA double-strand breaks in Escherichia coli
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24363387
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24363387
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
SnapShot: Homologous recombination in DNA double-strand break repair
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24363387
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1259/BJR.20130685
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
682868
OpenCitations bibliographic resource ID
682868
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
682868
PMCID
4064598
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
682868
PubMed ID
24363387
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
682868
ResearchGate publication ID
259449487
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