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Cell polarisation and the immunological synapse
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PubMed
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PubMed
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12 October 2019
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PubMed
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18 October 2019
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PubMed
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23 July 2020
title
Cell polarisation and the immunological synapse
(English)
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PubMed
main subject
cell
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PubMed
retrieved
12 October 2019
hemic and immune systems
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PubMed
retrieved
18 October 2019
cell polarity
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PubMed
retrieved
23 July 2020
immunology
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inferred from title
author
Gillian Griffiths
object named as
Gillian M Griffiths
series ordinal
2
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author name string
Karen L Angus
series ordinal
1
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language of work or name
English
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PubMed
publication date
February 2013
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PubMed
1 February 2013
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PubMed Central
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12 October 2019
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PubMed Central
retrieved
18 October 2019
stated in
PubMed Central
retrieved
23 July 2020
number of pages
7
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inferred from page(s)
published in
Current Opinion in Cell Biology
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PubMed
stated in
PubMed Central
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12 October 2019
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PubMed Central
retrieved
18 October 2019
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PubMed Central
retrieved
23 July 2020
volume
25
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PubMed
issue
1
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PubMed
page(s)
85-91
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PubMed
copyright license
Creative Commons Attribution 4.0 International
3 references
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Europe PubMed Central
retrieved
12 October 2019
stated in
Europe PubMed Central
retrieved
18 October 2019
stated in
Europe PubMed Central
retrieved
23 July 2020
copyright status
copyrighted
0 references
cites work
Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
Paxillin: a new vinculin-binding protein present in focal adhesions
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
The immunological synapse: a molecular machine controlling T cell activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
Three-dimensional segregation of supramolecular activation clusters in T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
Myosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
21 March 2017
F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Photocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Casein kinase I delta controls centrosome positioning during T cell activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
CD4+ T-cell synapses involve multiple distinct stages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Actomyosin II contractility expels von Willebrand factor from Weibel-Palade bodies during exocytosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Role for the actomyosin complex in regulated exocytosis revealed by intravital microscopy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
VAMP4- and VAMP7-expressing vesicles are both required for cytotoxic granule exocytosis in NK cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
IQGAP1 involvement in MTOC and granule polarization in NK-cell cytotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
High-resolution imaging of the immunological synapse and T-cell receptor microclustering through microfabricated substrates.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Two modes of lytic granule fusion during degranulation by natural killer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Centrosome docking at the immunological synapse is controlled by Lck signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Molecular mechanisms of centrosome and cytoskeleton anchorage at the nuclear envelope.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
The exocytosis of lytic granules is impaired in Vti1b- or Vamp8-deficient CTL leading to a reduced cytotoxic activity following antigen-specific activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
T cell activation at the immunological synapse: vesicles emerge for LATer signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
The immunological synapse: a focal point for endocytosis and exocytosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Secretory mechanisms in cell-mediated cytotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Cilia and centrosomes: a unifying pathogenic concept for cystic kidney disease?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
The mature activating natural killer cell immunologic synapse is formed in distinct stages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Primary cilia in normal and pathological tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 September 2017
Cytotoxic T lymphocyte effector function is independent of nucleus-centrosome dissociation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
31 May 2018
Stathmin regulates microtubule dynamics and microtubule organizing center polarization in activated T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
31 May 2018
A role for Rab7 in the movement of secretory granules in cytotoxic T lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
31 May 2018
Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 November 2018
Paxillin associates with the microtubule cytoskeleton and the immunological synapse of CTL through its leucine-aspartic acid domains and contributes to microtubule organizing center reorientation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 November 2018
Dynein-Driven Transport of T Cell Receptor Microclusters Regulates Immune Synapse Formation and T Cell Activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 November 2018
B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 November 2018
Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 November 2018
Centrosome polarization delivers secretory granules to the immunological synapse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 November 2018
The immunological synapse of CTL contains a secretory domain and membrane bridges.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3712171
retrieved
28 November 2018
Identifiers
DOI
10.1016/J.CEB.2012.08.013
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856642
OpenCitations bibliographic resource ID
1856642
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856642
PMC publication ID
3712171
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856642
PubMed publication ID
22990072
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856642
ResearchGate publication ID
230879185
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