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Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors
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title
Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors
(English)
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stated in
PubMed
main subject
G protein-coupled receptor
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author name string
J. A. Ardura
series ordinal
1
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Crossref
P. A. Friedman
series ordinal
2
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Crossref
language of work or name
English
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stated in
PubMed
publication date
December 2011
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PubMed
published in
Pharmacological Reviews
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PubMed
volume
63
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PubMed
issue
4
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stated in
PubMed
page(s)
882-900
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PubMed
cites work
Ongoing and future developments at the Universal Protein Resource
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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21 March 2017
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PubMed Central
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PubMed Central
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NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands
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PubMed Central
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NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin
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PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor
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A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins
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21 March 2017
The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
1 reference
stated in
PubMed Central
reference URL
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1 reference
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PubMed Central
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1 reference
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PubMed Central
reference URL
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PubMed Central
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PubMed Central
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PubMed Central
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21 March 2017
Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains
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PubMed Central
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21 March 2017
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PubMed Central
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1 reference
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PubMed Central
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21 March 2017
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1 reference
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PubMed Central
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21 March 2017
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PubMed Central
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21 March 2017
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21 March 2017
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21 March 2017
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21 March 2017
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21 March 2017
G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction
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PubMed Central
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21 March 2017
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A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled ...
1 reference
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21 March 2017
kappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteins
1 reference
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21 March 2017
An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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21 March 2017
Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)
1 reference
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PubMed Central
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21 March 2017
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21 March 2017
Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice
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21 March 2017
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21 March 2017
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21 March 2017
Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells
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21 March 2017
Longitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null mice
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21 March 2017
Ezrin-radixin-moesin (ERM)-binding phosphoprotein 50 organizes ERM proteins at the apical membrane of polarized epithelia
1 reference
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21 March 2017
Molecular cloning of the cDNA and promoter sequences for the mouse sodium-hydrogen exchanger regulatory factor
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21 March 2017
Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities
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21 March 2017
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21 March 2017
Recognition of unique carboxyl-terminal motifs by distinct PDZ domains
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7 April 2017
ERM proteins and merlin: integrators at the cell cortex
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7 April 2017
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
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7 April 2017
NHERF2 is necessary for basal activity, second messenger inhibition, and LPA stimulation of NHE3 in mouse distal ileum
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28 September 2017
Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles
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28 September 2017
Role of PDZK1 protein in apical membrane expression of renal sodium-coupled phosphate transporters
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28 September 2017
MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells.
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28 September 2017
Dynamics of PTH-induced disassembly of Npt2a/NHERF-1 complexes in living OK cells
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28 September 2017
Role for ezrin in breast cancer cell chemotaxis to CCL5.
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28 September 2017
Na+/H+ exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer
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28 September 2017
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28 September 2017
Formation of a ternary complex among NHERF1, beta-arrestin, and parathyroid hormone receptor.
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28 September 2017
Role of NHERF and scaffolding proteins in proximal tubule transport
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28 September 2017
NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Na/H exchanger regulatory factors control parathyroid hormone receptor signaling by facilitating differential activation of G(alpha) protein subunits.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Nerve growth factor-regulated emergence of functional delta-opioid receptors
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Cell signaling in space and time: where proteins come together and when they're apart
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Fluorescence resonance energy transfer analysis of merlin conformational changes
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Opioid-receptor-heteromer-specific trafficking and pharmacology
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
The role of the NHERF family of PDZ scaffolding proteins in the regulation of salt and water transport
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Frizzled-PDZ scaffold interactions in the control of Wnt signaling
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Lysophosphatidic acid 2 receptor-mediated supramolecular complex formation regulates its antiapoptotic effect
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
NHERF1 regulates parathyroid hormone receptor desensitization: interference with beta-arrestin binding
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Roles of NHERF1/EBP50 in cancer
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Regulation of phosphate transport in proximal tubules.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Influence of PDZK1 on lipoprotein metabolism and atherosclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Constitutive and agonist-induced dimerizations of the P2Y1 receptor: relationship to internalization and scaffolding.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Regulation of parathyroid hormone type 1 receptor dynamics, traffic, and signaling by the Na+/H+ exchanger regulatory factor-1 in rat osteosarcoma ROS 17/2.8 cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Contact-dependent inhibition of EGFR signaling by Nf2/Merlin
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Cortical stabilization of beta-catenin contributes to NHERF1/EBP50 tumor suppressor function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
Suppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
The PDZ scaffold NHERF-2 interacts with mGluR5 and regulates receptor activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
The emerging role of PDZ adapter proteins for regulation of intestinal ion transport
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
Convergent and divergent ligand specificity among PDZ domains of the LAP and zonula occludens (ZO) families.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
Beyond the brush border: NHERF4 blazes new NHERF turf
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
NHERF family and NHE3 regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
P2Y1 receptor signaling is controlled by interaction with the PDZ scaffold NHERF-2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Protein kinase C regulates the phosphorylation and oligomerization of ERM binding phosphoprotein 50.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
Regulation of ion transport by the NHERF family of PDZ proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
The Na+/H+ exchanger regulatory factor stabilizes epidermal growth factor receptors at the cell surface
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
Stimulation of Xenopus P2Y1 receptor activates CFTR in A6 cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Opioid receptors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
Agonist-induced regulation and trafficking of kappa opioid receptors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Stimulation by parathyroid hormone of a NHERF-1-assembled complex consisting of the parathyroid hormone I receptor, phospholipase Cbeta, and actin increases intracellular calcium in opossum kidney cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Galphaq-coupled receptor internalization specifically induced by Galphaq signaling. Regulation by EBP50.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epithelia
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Targeted disruption of the PDZK1 gene by homologous recombination
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
A macromolecular complex of beta 2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKA
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Expression profiling of mammary carcinoma cell lines: correlation of in vitro invasiveness with expression of CD24.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Estrogen receptor inducibility of the human Na+/H+ exchanger regulatory factor/ezrin-radixin-moesin binding protein 50 (NHE-RF/EBP50) gene involving multiple half-estrogen response elements
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Structural requirements for the apical sorting of human multidrug resistance protein 2 (ABCC2).
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Distinct cell type-specific expression of scaffolding proteins EBP50 and E3KARP: EBP50 is generally expressed with ezrin in specific epithelia, whereas E3KARP is not.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
Expanding the role of NHERF, a PDZ-domain containing protein adapter, to growth regulation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Oligomerization of NHERF-1 and NHERF-2 PDZ domains: differential regulation by association with receptor carboxyl-termini and by phosphorylation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 September 2017
Preferential cytoplasmic localization of delta-opioid receptors in rat striatal patches: comparison with plasmalemmal mu-opioid receptors.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
N-terminal PDZ domain is required for NHERF dimerization
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
ERM-Merlin and EBP50 protein families in plasma membrane organization and function
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Evidence for ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) self-association through PDZ-PDZ interactions
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Molecular mechanisms and regulation of opioid receptor signaling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
cAMP-induced phosphorylation and inhibition of Na(+)/H(+) exchanger 3 (NHE3) are dependent on the presence but not the phosphorylation of NHE regulatory factor
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
The role of NHERF and E3KARP in the cAMP-mediated inhibition of NHE3.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Structure-function of recombinant Na/H exchanger regulatory factor (NHE-RF)
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Identification of a new gene product (diphor-1) regulated by dietary phosphate.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Functional beta3-adrenoceptor in the human heart
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
CAMP-mediated inhibition of the renal brush border membrane Na+-H+ exchanger requires a dissociable phosphoprotein cofactor
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Regulation of the renal brush border membrane Na(+)-H+ exchanger
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
Purinoceptors: are there families of P2X and P2Y purinoceptors?
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 September 2017
PDZK1 regulates organic anion transporting polypeptide Oatp1a in mouse small intestine.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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31 May 2018
Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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31 May 2018
CCR5Delta32 protein expression and stability are critical for resistance to human immunodeficiency virus type 1 in vivo
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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31 May 2018
Type-specific sorting of G protein-coupled receptors after endocytosis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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31 May 2018
The carboxyl-terminal region of EBP50 binds to a site in the amino-terminal domain of ezrin that is masked in the dormant molecule
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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31 May 2018
Ezrin: a protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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31 May 2018
Identification of sites required for down-regulation of Na+/H+ exchanger NHE3 activity by cAMP-dependent protein kinase. phosphorylation-dependent and -independent mechanisms
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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31 May 2018
Relationship between airway ion transport and a mild pulmonary disease mutation in CFTR.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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31 May 2018
Identification of a putative Na(+)-H+ exchanger regulatory cofactor in rabbit renal BBM.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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31 May 2018
Subtype-specific role of phospholipase C-beta in bradykinin and LPA signaling through differential binding of different PDZ scaffold proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
Biological role of NHERF1 protein expression in breast cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
NHERF1 regulates parathyroid hormone receptor membrane retention without affecting recycling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 November 2018
NHERF-1 and the cytoskeleton regulate the traffic and membrane dynamics of G protein-coupled receptors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
New insights into cystic fibrosis: molecular switches that regulate CFTR
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
Adenoviral expression of NHERF-1 in NHERF-1 null mouse renal proximal tubule cells restores Npt2a regulation by low phosphate media and parathyroid hormone.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
Emergence of functional delta-opioid receptors induced by long-term treatment with morphine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
Defective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
LPA2 receptor mediates mitogenic signals in human colon cancer cells
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 November 2018
Defective parathyroid hormone regulation of NHE3 activity and phosphate adaptation in cultured NHERF-1-/- renal proximal tubule cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
Ezrin, a key component in tumor metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 November 2018
Ligand-selective dissociation of activation and internalization of the parathyroid hormone (PTH) receptor: conditional efficacy of PTH peptide fragments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
Ligand-induced recruitment of Na+/H+-exchanger regulatory factor to the PDGF (platelet-derived growth factor) receptor regulates actin cytoskeleton reorganization by PDGF.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 November 2018
Na+/H+ exchanger-regulatory factor 1 mediates inhibition of phosphate transport by parathyroid hormone and second messengers by acting at multiple sites in opossum kidney cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
retrieved
28 November 2018
Stimulation of beta 2-adrenergic receptor increases cystic fibrosis transmembrane conductance regulator expression in human airway epithelial cells through a cAMP/protein kinase A-independent pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
Thromboxane A2 signalling in humans: a 'Tail' of two receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186079
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28 November 2018
Functional coupling of the beta 2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A receptor activity modifying protein (RAMP)2-dependent adrenomedullin receptor is a calcitonin gene-related peptide receptor when coexpressed with human RAMP1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Na-H exchanger regulatory factor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Down regulation of small intestinal ion transport in PDZK1- (CAP70/NHERF3) deficient mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Stimulation of anion secretion by beta-adrenoceptors in the mouse endometrial epithelium
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Differential renal distribution of NHERF isoforms and their colocalization with NHE3, ezrin, and ROMK
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
PDZ-binding motifs are unable to ensure correct polarized protein distribution in the absence of additional localization signals
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Protein kinase C phosphorylation disrupts Na+/H+ exchanger regulatory factor 1 autoinhibition and promotes cystic fibrosis transmembrane conductance regulator macromolecular assembly
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression and clinicopathological significance of oestrogen-responsive ezrin-radixin-moesin-binding phosphoprotein 50 in breast cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Parathyroid hormone stimulation of calcium transport is mediated by dual signaling mechanisms involving protein kinase A and protein kinase C
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Estrogen receptor regulation of the Na+/H+ exchange regulatory factor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Adenosine receptors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21873413
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1124/PR.110.004176
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4515190
OpenCitations bibliographic resource ID
4515190
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4515190
PMC publication ID
3186079
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4515190
PubMed publication ID
21873413
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4515190
ResearchGate publication ID
51601439
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